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Research Output 1997 2019

  • 585 Citations
  • 10 h-Index
  • 18 Article
  • 1 Review article
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Article
2019
1 Citation (Scopus)
Open Access
Health
Aptitude
Translational Medical Research
Organized Financing
Self Efficacy
2012
33 Citations (Scopus)

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

Sabnis, N., Nair, M. P., Israel, M., McConathy, W. J. & Lacko, A. G., 5 Dec 2012, In : International Journal of Nanomedicine. 7, p. 975-983 9 p.

Research output: Contribution to journalArticleResearchpeer-review

valrubicin
Lipoproteins
Encapsulation
Nanoparticles
Solubility
2011
128 Citations (Scopus)

Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

Shahzad, M. M. K., Mangala, L. S., Han, H. D., Lu, C., Bottsford-Miller, J., Nishimura, M., Mora, E. M., Lee, J. W., Stone, R. L., Pecot, C. V., Thanapprapasr, D., Roh, J. W., Gaur, P., Nair, M. P., Park, Y. Y., Sabnis, N., Deavers, M. T., Lee, J. S., Ellis, L. M., Lopez-Berestei, G. & 4 others, McConathy, W. J., Prokai, L., Lacko, A. G. & Sood, A. K., 1 Jan 2011, In : Neoplasia. 13, 4, p. 309-319 11 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Nanoparticles
Small Interfering RNA
Scavenger Receptors
Neoplasms
10 Citations (Scopus)

Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF)

McConathy, W. J., Paranjape, S., Mooberry, L., Buttreddy, S., Nair, M. P. & Lacko, A. G., 1 Apr 2011, In : Drug Delivery and Translational Research. 1, 2, p. 113-120 8 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Fluorescein
Pharmaceutical Preparations
Hydrolysis
lauric acid
2010
81 Citations (Scopus)

Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier

Mooberry, L. K., Nair, M. P., Paranjape, S., McConathy, W. J. & Lacko, A. G., 1 Jan 2010, In : Journal of Drug Targeting. 18, 1, p. 53-58 6 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Paclitaxel
Scavenger Receptors
Nanoparticles
Pharmaceutical Preparations
2008
10 Citations (Scopus)

Binding of 8-anilino-1-naphthalenesulfonate to lecithin:cholesterol acyltransferase studied by fluorescence techniques

Sarkar, P., Bharill, S., Gryczynski, I., Gryczynski, Z., Nair, M. P. & Lacko, A. G., 24 Jul 2008, In : Journal of Photochemistry and Photobiology B: Biology. 92, 1, p. 19-23 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Anilino Naphthalenesulfonates
Phosphatidylcholine-Sterol O-Acyltransferase
cholesterol
Fluorescence
fluorescence
94 Citations (Scopus)

Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel

McConathy, W. J., Nair, M. P., Paranjape, S., Mooberry, L. & Lacko, A. G., 1 Feb 2008, In : Anti-Cancer Drugs. 19, 2, p. 183-188 6 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Paclitaxel
Nanoparticles
Ultracentrifugation
Inhibitory Concentration 50
2007
26 Citations (Scopus)

Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer

Singhal, S. S., Singhal, J., Nair, M. P., Lacko, A. G., Awasthi, Y. C. & Awasthi, S., 1 Mar 2007, In : International Journal of Oncology. 30, 3, p. 717-725 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Doxorubicin
Lung Neoplasms
Breast Neoplasms
Cell Line
Small Cell Lung Carcinoma
2006
4 Citations (Scopus)

Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase

Reshetnyak, Y., Tchedre, K. T., Nair, M. P., Pritchard, P. H. & Lacko, A. G., 1 Jan 2006, In : Journal of Biomolecular Structure and Dynamics. 24, 1, p. 75-82 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Lecithin Cholesterol Acyltransferase Deficiency
Phosphatidylcholine-Sterol O-Acyltransferase
HDL Lipoproteins
Tryptophan
Acrylamide
25 Citations (Scopus)

Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model

Lacko, A. G., Nair, M. P., Paranjape, S., Mooberry, L. & McConathy, W. J., 1 Jun 2006, In : Chemotherapy. 52, 4, p. 171-173 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Magic
HDL Lipoproteins
Pharmaceutical Preparations
2004
5 Citations (Scopus)

Characterization of lecithin:cholesterol acyltransferase expressed in a human lung cell line

Lane, S. B., Tchedre, K. T., Nair, M. P., Thigpen, A. E. & Lacko, A. G., 1 Aug 2004, In : Protein Expression and Purification. 36, 2, p. 157-164 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphatidylcholine-Sterol O-Acyltransferase
Cell Line
Lung
Enzyme Replacement Therapy
Lecithin Cholesterol Acyltransferase Deficiency
2002
78 Citations (Scopus)

High density lipoprotein complexes as delivery vehicles for anticancer drugs

Lacko, A. G., Nair, M. P., Paranjape, S., Johnson, S. & McConathy, W. J., 19 Aug 2002, In : Anticancer Research. 22, 4, p. 2045-2049 5 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Pharmaceutical Preparations
Cholesterol Esters
Paclitaxel
Scavenger Receptors
2001
7 Citations (Scopus)

Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies

Murray, K. R., Nair, M. P., Ayyobi, A. F., Hill, J. S., Pritchard, P. H. & Lacko, A. G., 15 Jan 2001, In : Archives of Biochemistry and Biophysics. 385, 2, p. 267-275 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphatidylcholine-Sterol O-Acyltransferase
Antibodies
Enzymes
Mutation
Immunoassay
2000
9 Citations (Scopus)

Biochemical and compositional analyses of recombinant lecithin:cholesterol acyltransferase (LCAT) obtained from a hepatic source

Ayyobi, A. F., Lacko, A. G., Murray, K., Nair, M. P., Li, M., Molhuizen, H. O. F. & Pritchard, P. H., 24 Feb 2000, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1484, 1, p. 1-13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphatidylcholine-Sterol O-Acyltransferase
Liver
Cricetinae
Glycoproteins
Oligosaccharides
1999

Enzyme linked immunoassay (ELISA) for lecithin:cholesterol acyltransferase (LCAT)

Murray, K. R., Nair, M. P., McConathy, W. J. & Lacko, A. G., 1 Jan 1999, In : Analytical Letters. 32, 8, p. 1553-1564 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphatidylcholine-Sterol O-Acyltransferase
Lecithin
Cholesterol
Immunoenzyme Techniques
Immunoassay
1998
13 Citations (Scopus)

Characterization of recombinant human plasma lecithin: Cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

Lacko, A. G., Reason, A. J., Nuckolls, C., Kudchodkar, B. J., Nair, M. P., Sundarrajan, G., Pritchard, P. H., Morris, H. R. & Dell, A., 1 Apr 1998, In : Journal of Lipid Research. 39, 4, p. 807-820 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasma (human)
Phosphatidylcholine-Sterol O-Acyltransferase
Carbohydrates
Polysaccharides
Oligosaccharides

Lipoprotein substrate binding site of LCAT karen murray

Nair, M. P., Haydn Pritchard, P. & Lacko, A. G., 1 Dec 1998, In : FASEB Journal. 12, 8

Research output: Contribution to journalArticleResearchpeer-review

Lipoproteins
Binding Sites
Antibodies
Substrates
Enzymes
1997
4 Citations (Scopus)

Purification of recombinant lecithin:cholesterol acyltransferase

Nair, M. P., Kudchodkar, B. J., Pritchard, P. H. & Lacko, A. G., 1 Jan 1997, In : Protein Expression and Purification. 10, 1, p. 38-41 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphatidylcholine-Sterol O-Acyltransferase
Conditioned Culture Medium
Cricetinae
Chromatography
Kidney