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Research Output 1997 2019

  • 624 Citations
  • 10 h-Index
  • 19 Article
  • 2 Review article
1 Citation (Scopus)
Open Access
Health
Aptitude
Translational Medical Research
Organized Financing
Self Efficacy
10 Citations (Scopus)
Anilino Naphthalenesulfonates
Phosphatidylcholine-Sterol O-Acyltransferase
cholesterol
Fluorescence
fluorescence
9 Citations (Scopus)

Biochemical and compositional analyses of recombinant lecithin:cholesterol acyltransferase (LCAT) obtained from a hepatic source

Ayyobi, A. F., Lacko, A. G., Murray, K., Nair, M. P., Li, M., Molhuizen, H. O. F. & Pritchard, P. H., 24 Feb 2000, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1484, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Phosphatidylcholine-Sterol O-Acyltransferase
Liver
Cricetinae
Glycoproteins
Oligosaccharides
5 Citations (Scopus)

Characterization of lecithin:cholesterol acyltransferase expressed in a human lung cell line

Lane, S. B., Tchedre, K. T., Nair, M. P., Thigpen, A. E. & Lacko, A. G., 1 Aug 2004, In : Protein Expression and Purification. 36, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

Phosphatidylcholine-Sterol O-Acyltransferase
Cell Line
Lung
Enzyme Replacement Therapy
Lecithin Cholesterol Acyltransferase Deficiency
13 Citations (Scopus)

Characterization of recombinant human plasma lecithin: Cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

Lacko, A. G., Reason, A. J., Nuckolls, C., Kudchodkar, B. J., Nair, M. P., Sundarrajan, G., Pritchard, P. H., Morris, H. R. & Dell, A., 1 Apr 1998, In : Journal of Lipid Research. 39, 4, p. 807-820 14 p.

Research output: Contribution to journalArticle

Plasma (human)
Phosphatidylcholine-Sterol O-Acyltransferase
Carbohydrates
Polysaccharides
Oligosaccharides
27 Citations (Scopus)

Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer

Singhal, S. S., Singhal, J., Nair, M. P., Lacko, A. G., Awasthi, Y. C. & Awasthi, S., 1 Mar 2007, In : International journal of oncology. 30, 3, p. 717-725 9 p.

Research output: Contribution to journalArticle

Doxorubicin
Lung Neoplasms
Breast Neoplasms
Cell Line
Small Cell Lung Carcinoma
38 Citations (Scopus)

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

Sabnis, N., Nair, M., Israel, M., McConathy, W. J. & Lacko, A. G., 5 Dec 2012, In : International Journal of Nanomedicine. 7, p. 975-983 9 p.

Research output: Contribution to journalArticle

valrubicin
Lipoproteins
Encapsulation
Nanoparticles
Solubility

Enzyme linked immunoassay (ELISA) for lecithin:cholesterol acyltransferase (LCAT)

Murray, K. R., Nair, M. P., McConathy, W. J. & Lacko, A. G., 1 Jan 1999, In : Analytical Letters. 32, 8, p. 1553-1564 12 p.

Research output: Contribution to journalArticle

Phosphatidylcholine-Sterol O-Acyltransferase
Lecithin
Cholesterol
Immunoenzyme Techniques
Immunoassay
97 Citations (Scopus)

Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel

McConathy, W. J., Nair, M. P., Paranjape, S., Mooberry, L. & Lacko, A. G., 1 Feb 2008, In : Anti-Cancer Drugs. 19, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Paclitaxel
Nanoparticles
Ultracentrifugation
Inhibitory Concentration 50
82 Citations (Scopus)

High density lipoprotein complexes as delivery vehicles for anticancer drugs

Lacko, A. G., Nair, M. P., Paranjape, S., Johnson, S. & McConathy, W. J., 19 Aug 2002, In : Anticancer Research. 22, 4, p. 2045-2049 5 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Pharmaceutical Preparations
Cholesterol Esters
Paclitaxel
Scavenger Receptors

Lipoprotein substrate binding site of LCAT karen murray

Nair, M. P., Haydn Pritchard, P. & Lacko, A. G., 1 Dec 1998, In : FASEB Journal. 12, 8, p. A1379

Research output: Contribution to journalArticle

Lipoproteins
Binding Sites
Antibodies
Substrates
Enzymes
2 Citations (Scopus)

Ovarian cancer: Current status and strategies for improving therapeutic outcomes

Chandra, A., Pius, C., Nabeel, M., Nair, M., Vishwanatha, J. K., Ahmad, S. & Basha, R., 1 Nov 2019, In : Cancer Medicine. 8, 16, p. 7018-7031 14 p.

Research output: Contribution to journalReview article

Open Access
Ovarian Neoplasms
Platinum
Drug Therapy
Therapeutics
Survival Rate

Pancreatic cancer: An emphasis on current perspectives in immunotherapy

Patel, K., Siraj, S., Smith, C., Nair, M., Vishwanatha, J. K. & Basha, R., 1 Jan 2019, In : Critical Reviews in Oncogenesis. 24, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Immunotherapy
Neoplasms
Clinical Trials
Programmed Cell Death 1 Receptor
7 Citations (Scopus)

Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies

Murray, K. R., Nair, M. P., Ayyobi, A. F., Hill, J. S., Pritchard, P. H. & Lacko, A. G., 15 Jan 2001, In : Archives of Biochemistry and Biophysics. 385, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

Phosphatidylcholine-Sterol O-Acyltransferase
Antibodies
Enzymes
Mutation
Immunoassay
61 Citations (Scopus)

Prospects and challenges of the development of lipoprotein-based formulations for anti-cancer drugs

Lacko, A. G., Nair, M. P., Prokai, L. & McConarthy, W. J., 1 Nov 2007, In : Expert Opinion on Drug Delivery. 4, 6, p. 665-675 11 p.

Research output: Contribution to journalReview article

Lipoproteins
Pharmaceutical Preparations
Neoplasms
Drug Compounding
Drug Carriers
4 Citations (Scopus)

Purification of recombinant lecithin:cholesterol acyltransferase

Nair, M. P., Kudchodkar, B. J., Pritchard, P. H. & Lacko, A. G., 1 Jan 1997, In : Protein Expression and Purification. 10, 1, p. 38-41 4 p.

Research output: Contribution to journalArticle

Phosphatidylcholine-Sterol O-Acyltransferase
Conditioned Culture Medium
Cricetinae
Chromatography
Kidney
87 Citations (Scopus)

Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier

Mooberry, L. K., Nair, M., Paranjape, S., McConathy, W. J. & Lacko, A. G., 1 Jan 2010, In : Journal of Drug Targeting. 18, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Paclitaxel
Scavenger Receptors
Nanoparticles
Pharmaceutical Preparations
4 Citations (Scopus)

Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase

Reshetnyak, Y., Tchedre, K. T., Nair, M. P., Pritchard, P. H. & Lacko, A. G., Aug 2006, In : Journal of Biomolecular Structure and Dynamics. 24, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Lecithin Cholesterol Acyltransferase Deficiency
Phosphatidylcholine-Sterol O-Acyltransferase
HDL Lipoproteins
Tryptophan
Acrylamide
141 Citations (Scopus)

Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

Shahzad, M. M. K., Mangala, L. S., Han, H. D., Lu, C., Bottsford-Miller, J., Nishimura, M., Mora, E. M., Lee, J. W., Stone, R. L., Pecot, C. V., Thanapprapasr, D., Roh, J. W., Gaur, P., Nair, M. P., Park, Y. Y., Sabnis, N., Deavers, M. T., Lee, J. S., Ellis, L. M., Lopez-Berestei, G. & 4 others, McConathy, W. J., Prokai, L., Lacko, A. G. & Sood, A. K., Apr 2011, In : Neoplasia. 13, 4, p. 309-319 11 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Nanoparticles
Small Interfering RNA
Scavenger Receptors
Neoplasms
26 Citations (Scopus)

Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model

Lacko, A. G., Nair, M. P., Paranjape, S., Mooberry, L. & McConathy, W. J., 1 Jun 2006, In : Chemotherapy. 52, 4, p. 171-173 3 p.

Research output: Contribution to journalArticle

Magic
HDL Lipoproteins
Pharmaceutical Preparations
10 Citations (Scopus)

Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF)

McConathy, W. J., Paranjape, S., Mooberry, L., Buttreddy, S., Nair, M. & Lacko, A. G., 1 Apr 2011, In : Drug Delivery and Translational Research. 1, 2, p. 113-120 8 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Fluorescein
Pharmaceutical Preparations
Hydrolysis
lauric acid