Projects per year
Personal profile
Area of Expertise
My research focuses on determining the neural changes associated with neuropsychiatric disorders particularly with an special emphasis on substance use disorders. I integrate computational neuroscience methods to broad applications in neuropsychiatric disorders and preclinical models of mental health disorders. I specifically work in the field of neuroimaging and the recent neuroscience filed of “connectomics.” In this area, we seek to quantitatively identify important insights about brain networks’ physical properties or “connectomes” to gain new insights on behavior and cognition.
To date, my research initiatives have focused on developing and applying quantitative neuroimaging tools to study the brain’s structure and function. Specifically, we merge diffusion and functional MRI with complex network analysis, which is the field of physics devoted to understanding the properties of networks, to reveal topological features of brain connectivity. More recently, we are focused on computational neuroscience approaches to investigate disease-related brain topology, particularly in animal models of substance use disorders.
Education/Academic qualification
PhD Physics, University of Florida
BS Physics, University of Puerto Rico
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Projects
- 1 Active
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Reduced structural connectivity of the medial temporal lobe including the perforant path is associated with aging and verbal memory impairment
Granger, S. J., Colon-Perez, L., Larson, M. S., Bennett, I. J., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H. & Yassa, M. A., Jan 2023, In: Neurobiology of Aging. 121, p. 119-128 10 p.Research output: Contribution to journal › Article › peer-review
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Touchscreen-Based Cognitive Training Alters Functional Connectivity Patterns in Aged But Not Young Male Rats
Gaynor, L. S., Ravi, M., Zequeira, S., Hampton, A. M., Pyon, W. S., Smith, S., Colon-Perez, L. M., Pompilus, M., Bizon, J. L., Maurer, A. P., Febo, M. & Burke, S. N., Feb 2023, In: eNeuro. 10, 2, ENEURO.0329-22.2023.Research output: Contribution to journal › Article › peer-review
Open Access -
Hippocampal dentate gyrus integrity revealed with ultrahigh resolution diffusion imaging predicts memory performance in older adults
Granger, S. J., Colon-Perez, L., Larson, M. S., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H. & Yassa, M. A., Sep 2022, In: Hippocampus. 32, 9, p. 627-638 12 p.Research output: Contribution to journal › Article › peer-review
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The future of neuroimaging and gut-brain axis research for substance use disorders
Colon-Perez, L., Montesinos, J. & Monsivais, M., 15 Apr 2022, In: Brain Research. 1781, 147835.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Contextual experience modifies functional connectome indices of topological strength and efficiency
Pompilus, M., Colon-Perez, L. M., Grudny, M. M. & Febo, M., Dec 2020, In: Scientific Reports. 10, 1, 19843.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations