Liang-Jun Yan, PhD

Research output

Research output per year 1991 1995 1998 2007 2014 2015 2016 2017 2018 2019 2020 2023

• 75 Article
• 30 Review article
• 3 Editorial
• 2 Chapter
• 2 More
  • 1 Conference contribution
  • 1 Comment/debate

Research output per year

Research output per year

Search results

• Sources and implications of NADH/NAD⁺ redox imbalance in diabetes and its complications

  Wu, J., Jin, Z., Zheng, H. & Yan, L. J., 10 May 2016, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 9, p. 145-153 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Enzyme 100%
  • Antidiabetic Agent 100%
  • Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 100%
  • Lactate Dehydrogenase 100%
  • Hyperglycemia 100%

• The negative and detrimental effects of high fructose on the liver, with special reference to metabolic disorders

  Mai, B. H. & Yan, L. J., 2019, In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12, p. 821-826 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Liver 100%
  • Detrimental Effects 100%
  • Metabolic Disorders 100%
  • Negative Effects 100%
  • High Fructose 100%

• Vagus nerve stimulation as a promising adjunctive treatment for ischemic stroke

  Ma, J., Qiao, P., Li, Q., Wang, Y., Zhang, L., Yan, L. J. & Cai, Z., Dec 2019, In: Neurochemistry International. 131, 104539.

  Research output: Contribution to journal › Review article › peer-review

  • Ischemic Stroke 100%
  • Adjunctive Therapy 100%
  • Vagus Nerve Stimulation 100%
  • Brain Ischemia 100%
  • Cerebrovascular Accident 30%

• Potential biochemical mechanisms of brain injury in diabetes mellitus

  Ma, W. X., Tang, J., Lei, Z. W., Li, C. Y., Zhao, L. Q., Lin, C., Sun, T., Li, Z. Y., Jiang, Y. H., Jia, J. T., Liang, C. Z., Liu, J. H. & Yan, L. J., 2020, In: Aging and Disease. 11, 4, p. 978-987 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Brain Injury 100%
  • Diabetes 100%
  • Biochemical Mechanism 100%
  • Type 1 Diabetes Mellitus (T1DM) 100%
  • Diabetic Cognitive Impairment 100%

• The Nicotinamide/Streptozotocin Rodent Model of Type 2 Diabetes: Renal Pathophysiology and Redox Imbalance Features

  Yan, L. J., Sep 2022, In: Biomolecules. 12, 9, 1225.

  Research output: Contribution to journal › Review article › peer-review

  • Type 2 Diabetes Mellitus (T2DM) 100%
  • Redox Balance 100%
  • Rodent Models 100%
  • Diabetic Nephropathy 100%
  • Renal Pathophysiology 100%

• Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD⁺-Dependent Enzymes and Plant-Derived Natural Products

  Iskander, A. & Yan, L. J., Aug 2022, In: Biomolecules. 12, 8, 1078.

  Research output: Contribution to journal › Review article › peer-review

  • Cisplatin-induced 100%
  • Cisplatin-induced Kidney Injury 100%
  • Toxicity Potential 100%
  • Plant Natural Products 100%
  • Kidney Toxicity 100%

• Renal-Protective Roles of Lipoic Acid in Kidney Disease

  Kamt, S. F., Liu, J. & Yan, L. J., Apr 2023, In: Nutrients. 15, 7, 1732.

  Research output: Contribution to journal › Review article › peer-review

  • Protective Behavior 100%
  • Kidney Disease 100%
  • Lipoic Acid 100%
  • Kidney Injury 100%
  • Renal Protection 100%

• Roles of Dihydrolipoamide Dehydrogenase in Health and Disease

  Yan, L. J. & Wang, Y., 1 Oct 2023, In: Antioxidants and Redox Signaling. 39, 10-12, p. 794-806 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dihydrolipoamide Dehydrogenase 100%
  • Disease 100%
  • Pathological Conditions 42%
  • Redox 14%
  • Non-redox 14%

• Redox imbalance stress in diabetes mellitus: Role of the polyol pathway

  Yan, L. J., Mar 2018, In: Animal Models and Experimental Medicine. 1, 1, p. 7-13 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Diabetes 100%
  • Redox Balance 100%
  • Type 1 Diabetes Mellitus (T1DM) 100%
  • Polyol Pathway 100%
  • Sorbitol 100%

• Roles of Pyruvate, NADH, and Mitochondrial Complex i in Redox Balance and Imbalance in β Cell Function and Dysfunction

  Luo, X., Li, R. & Yan, L. J., 2015, In: Journal of Diabetes Research. 2015, 512618.

  Research output: Contribution to journal › Review article › peer-review

  • Insulin Secretion 100%
  • Mitochondrial Complex I 100%
  • Redox Balance 100%
  • Cell Function 100%
  • Cell Dysfunction 100%

• Protein redox modification as a cellular defense mechanism against tissue ischemic injury

  Yan, L. J., 2014, In: Oxidative Medicine and Cellular Longevity. 2014, 343154.

  Research output: Contribution to journal › Review article › peer-review

  • Ischemic Injury 100%
  • Redox Transformation 100%
  • Cellular Defense Mechanism 100%
  • Protein Function 100%
  • Cellular Immunity 100%

• Chemical probes for analysis of carbonylated proteins: A review

  Yan, L. J. & Forster, M. J., 15 May 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 17-18, p. 1308-1315 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Carbonyl Group 100%
  • Blue 100%
  • Carbonylation 100%
  • Sodium Borohydride 100%
  • Near-Infrared Imaging 100%

• Positive oxidative stress in aging and aging-related disease tolerance

  Yan, L. J., Apr 2014, In: Redox Biology. 2, 1, p. 165-169 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Oxidative Stress 100%
  • Aging 100%
  • Age-related Illnesses 100%
  • Disease Tolerance 100%
  • Reactive Oxygen Metabolite 100%

• Cadmium-induced kidney injury: Oxidative damage as a unifying mechanism

  Yan, L. J. & Allen, D. C., Nov 2021, In: Biomolecules. 11, 11, 1575.

  Research output: Contribution to journal › Review article › peer-review

  • Oxidative Damage 100%
  • Cadmium 100%
  • Kidney Injury 100%
  • Cell Death 100%
  • Respiratory Chain 100%

• NADH/NAD⁺ redox imbalance and diabetic kidney disease

  Yan, L. J., May 2021, In: Biomolecules. 11, 5, 730.

  Research output: Contribution to journal › Review article › peer-review

  • Nicotinamide Adenine Dinucleotide (NAD+) 100%
  • Redox Balance 100%
  • Diabetic Kidney Disease 100%
  • Diabetic Nephropathy 100%
  • Diabetes Mellitus 28%

• Roles of AMP-activated protein kinase in Alzheimer's disease

  Cai, Z., Yan, L. J., Li, K., Quazi, S. H. & Zhao, B., Mar 2012, In: NeuroMolecular Medicine. 14, 1, p. 1-14 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer's Disease 100%
  • AMP-activated Protein Kinase 100%
  • Tau 38%
  • Kinase Activation 23%
  • Tau Phosphorylation 23%

• Chemical conditioning as an approach to ischemic stroke tolerance: Mitochondria as the target

  Jin, Z., Wu, J. & Yan, L. J., 8 Mar 2016, In: International journal of molecular sciences. 17, 3, 351.

  Research output: Contribution to journal › Review article › peer-review

  • Ischemic Stroke 100%
  • Mitochondria 100%
  • Chemical Conditioning 100%
  • Brain Ischemia 100%
  • Mitochondrion 100%

• Cerebral small vessel disease and Alzheimer’s disease

  Cai, Z., Wang, C., He, W., Tu, H., Tang, Z., Xiao, M. & Yan, L. J., 2015, In: Clinical interventions in aging. 10, p. 1695-1704 10 p., A196.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer's Disease 100%
  • Cerebral Small Vessel Disease (cSVD) 100%
  • Cerebrovascular Disease 100%
  • Lacunar Stroke 25%
  • Statins 16%

• Telomere Shortening and Alzheimer's Disease

  Cai, Z., Yan, L. J. & Ratka, A., Mar 2013, In: NeuroMolecular Medicine. 15, 1, p. 25-48 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer's Disease 100%
  • Telomere Shortening 100%
  • Telomere Length 66%
  • Telomere 66%
  • Genetics 33%

• Analysis of oxidative modification of proteins

  Yan, L. J., 2009, In: Current Protocols in Protein Science. SUPPL. 55, p. 14.4.1-14.4.27

  Research output: Contribution to journal › Review article › peer-review

  • 3 Nitrotyrosine 100%
  • Thiol 100%
  • Oxidized Proteins 100%
  • Tyrosine 100%
  • Protein Carbonyls 66%

• Role of insulin resistance in Alzheimer’s disease

  Cai, Z., Xiao, M., Chang, L. & Yan, L. J., 1 Aug 2015, In: Metabolic Brain Disease. 30, 4, p. 839-851 13 p., A001.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer's Disease 100%
  • Insulin Resistance 100%
  • Secretase 75%
  • Oxidative Stress 75%
  • Neurofibrillary Tangles 25%

• Potential biochemical mechanisms of lung injury in diabetes

  Zheng, H., Wu, J., Jin, Z. & Yan, L. J., 2017, In: Aging and Disease. 8, 1, p. 7-16 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Protein Kinase C 100%
  • Protein Kinases 100%
  • Oxidative Stress 100%
  • Cell Damage 100%
  • Protein Glycosylation 100%

• Role and possible mechanisms of sirt1 in depression

  Lu, G., Li, J., Zhang, H., Zhao, X., Yan, L. J. & Yang, X., 2018, In: Oxidative Medicine and Cellular Longevity. 2018, 8596903.

  Research output: Contribution to journal › Review article › peer-review

  • Possible Mechanisms 100%
  • Role Mechanism 100%
  • Sirtuin 1 (SIRT1) 100%
  • Silent Information Regulator Protein 100%
  • Disease 33%

• Folic acid-induced animal model of kidney disease

  Yan, L. J., Dec 2021, In: Animal Models and Experimental Medicine. 4, 4, p. 329-342 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Kidney Disease 100%
  • Folic Acid 100%
  • Acid Activation 100%
  • Acute Kidney Injury 71%
  • Chronic Kidney Failure 71%

• Circulating factors in young blood as potential therapeutic agents for age-related neurodegenerative and neurovascular diseases

  Ma, J., Gao, B., Zhang, K., Zhang, Q., Jia, G., Li, J., Li, C., Yan, L. J. & Cai, Z., Nov 2019, In: Brain Research Bulletin. 153, p. 15-23 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Potential Therapeutics 100%
  • Age-related Neurodegeneration 100%
  • Young Blood 100%
  • Neurovascular Disease 100%
  • Circulating Factors 100%