Projects per year
Personal profile
Area of Expertise
The DLDH project studies its adaptive response as a viable druggable target for induction of stroke- or hypoxia tolerance and the mechanisms of this protein’s oxidative modifications in redox signaling and neuroprotection.
The complex I project on studies the mechanisms of complex I adaptive hyperactivity observed in diabetic pancreas and other tissues with the goal of exploring strategies that down-regulating complex I hyperactivity by restoring NADH/NAD redox balance may serve as a therapeutic approach for treating diabetes mellitus.
Education/Academic qualification
MS in Biochemistry, Chinese Academy of Sciences
BS in Biochemistry, Peking University
PhD in Biochemistry, University of California at Berkeley
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Projects
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Texas Center of Minority Health, Education, Research and Outreach - Project 2
Clay, P., Yan, L. & Suzuki, S.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
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Texas Center of Minority Health, Education, Research and Outreach - Project 2
Clay, P., Yan, L. & Suzuki, S.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
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Role of Transcellular Mitophagy in Diabetic Retinal Neurodegeneration
1/09/16 → 31/08/18
Project: Research
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Role of Transcellular Mitophagy in Diabetic Retinal Neurodegeneration
1/09/16 → 31/08/18
Project: Research
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Pancreatic Mitochondrial Complex I as a Target for Diabetes Therapy
1/05/16 → 31/08/17
Project: Research
Research output
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Editorial: Diabetes and Obesity Effects on Lung Function
Chen, X. F., Yan, L. J., Lecube, A. & Tang, X., 16 Jul 2020, In: Frontiers in Endocrinology. 11, 462.Research output: Contribution to journal › Editorial
Open Access2 Scopus citations -
Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke
Sumien, N., Huang, R., Chen, Z., Vann, P. H., Wong, J. M., Li, W., Yang, S., Forster, M. J. & Yan, L. J., 27 Jan 2020, In: Behavioural Brain Research. 378, 112278.Research output: Contribution to journal › Article › peer-review
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Effects of mesencephalic astrocyte-derived neurotrophic factor on cerebral angiogenesis in a rat model of cerebral ischemia
Gao, B., Deng, J., Zhang, X., Sun, H., Jia, G., Li, J., Zhang, K., Wan, C., Wang, L., Yan, L. J., Cai, Z. & Ma, J., 10 Jan 2020, In: Neuroscience letters. 715, p. 134657 1 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Neuroprotection of Cyperus esculentus L. orientin against cerebral ischemia/reperfusion induced brain injury
Jing, S. Q., Wang, S. S., Zhong, R. M., Zhang, J. Y., Wu, J. Z., Tu, Y. X., Pu, Y. & Yan, L. J., 1 Mar 2020, In: Neural Regeneration Research. 15, 3, p. 548-556 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Potential biochemical mechanisms of brain injury in diabetes mellitus
Ma, W. X., Tang, J., Lei, Z. W., Li, C. Y., Zhao, L. Q., Lin, C., Sun, T., Li, Z. Y., Jiang, Y. H., Jia, J. T., Liang, C. Z., Liu, J. H. & Yan, L. J., 2020, In: Aging and Disease. 11, 4, p. 978-987 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access