Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) protein oxidative modifications in aging-associated disease;
2) mechanisms of stroke prevention and stroke injury protection;
3) mitochondrial dysfunction and diabetes.
1) protein oxidative modifications in aging-associated disease;
2) mechanisms of stroke prevention and stroke injury protection;
3) mitochondrial dysfunction and diabetes.
Education/Academic qualification
PhD in Biochemistry, University of California at Berkeley
MS in Biochemistry, Chinese Academy of Sciences
BS in Biochemistry, Peking University
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Oxidative stress
Chemical Compounds
Dihydrolipoamide Dehydrogenase
Medicine & Life Sciences
Oxidative Stress
Medicine & Life Sciences
Proteins
Chemical Compounds
NAD
Medicine & Life Sciences
Antioxidants
Medicine & Life Sciences
Reactive Oxygen Species
Medicine & Life Sciences
Oxidation-Reduction
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2022
Texas Center of Minority Health, Education, Research and Outreach - Project 2
Clay, P., Yan, L. & Suzuki, S.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
Texas Center of Minority Health, Education, Research and Outreach - Project 2
Clay, P., Yan, L. & Suzuki, S.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
Role of Transcellular Mitophagy in Diabetic Retinal Neurodegeneration
1/09/16 → 31/08/17
Project: Research
Role of Transcellular Mitophagy in Diabetic Retinal Neurodegeneration
1/09/16 → 31/08/17
Project: Research
Pancreatic Mitochondrial Complex I as a Target for Diabetes Therapy
1/05/16 → 31/08/17
Project: Research
Research Output 1991 2019
Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress
Yang, X., Song, J. & Yan, L-J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Dihydrolipoamide Dehydrogenase
Oxidative stress
Oxidative Stress
Medical problems
Type 2 Diabetes Mellitus
2
Citations
(Scopus)
Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease
Zhao, Y. S., Zhang, L. H., Yu, P. P., Gou, Y. J., Zhao, J., You, L. H., Wang, Z. Y., Zheng, X., Yan, L-J., Yu, P. & Chang, Y. Z., 10 May 2018, In : Antioxidants and Redox Signaling. 28, 14, p. 1323-1337 15 p.Research output: Contribution to journal › Article › Research › peer-review
Ceruloplasmin
Alzheimer Disease
Therapeutics
Iron
Hippocampus
Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway
Yang, X., Zhang, H., Wu, J., Yin, L., Yan, L-J. & Zhang, C., 1 Oct 2018, In : International Journal of Molecular Sciences. 19, 10, 2982.Research output: Contribution to journal › Article › Research › peer-review
aspartates
JNK Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
N-Methylaspartate
Reactive Oxygen Species
5
Citations
(Scopus)
Post-ischemic administration of 5-methoxyindole-2-carboxylic acid at the onset of reperfusion affords neuroprotection against stroke injury by preserving mitochondrial function and attenuating oxidative stress
Wu, J., Jin, Z., Yang, X. & Yan, L-J., 26 Feb 2018, In : Biochemical and Biophysical Research Communications. 497, 1, p. 444-450 7 p.Research output: Contribution to journal › Article › Research › peer-review
Oxidative stress
Reperfusion
Oxidative Stress
Stroke
Wounds and Injuries
1
Citation
(Scopus)
Reexploring 5-methoxyindole-2-carboxylic acid (MICA) as a potential antidiabetic agent
Yan, L-J., 1 Jan 2018, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 11, p. 183-186 4 p.Research output: Contribution to journal › Article › Research › peer-review
Hypoglycemic Agents
Dihydrolipoamide Dehydrogenase
Glucose
Gluconeogenesis
Cricetulus