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Personal profile

Area of Expertise

Areas of research and interests include:
1) protein oxidative modifications in aging-associated disease;
2) mechanisms of stroke prevention and stroke injury protection;
3) mitochondrial dysfunction and diabetes.

Education/Academic qualification

PhD in Biochemistry, University of California at Berkeley

MS in Biochemistry, Chinese Academy of Sciences

BS in Biochemistry, Peking University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2022

Research Output 1991 2019

Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress

Yang, X., Song, J. & Yan, L-J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Dihydrolipoamide Dehydrogenase
Oxidative stress
Oxidative Stress
Medical problems
Type 2 Diabetes Mellitus

The negative and detrimental effects of high fructose on the liver, with special reference to metabolic disorders

Mai, B. H. & Yan, L-J., 1 Jan 2019, In : Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12, p. 821-826 6 p.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
Insulin Resistance
3 Citations (Scopus)

Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease

Zhao, Y. S., Zhang, L. H., Yu, P. P., Gou, Y. J., Zhao, J., You, L. H., Wang, Z. Y., Zheng, X., Yan, L-J., Yu, P. & Chang, Y. Z., 10 May 2018, In : Antioxidants and Redox Signaling. 28, 14, p. 1323-1337 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Alzheimer Disease
1 Citation (Scopus)

Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway

Yang, X., Zhang, H., Wu, J., Yin, L., Yan, L-J. & Zhang, C., 1 Oct 2018, In : International Journal of Molecular Sciences. 19, 10, 2982.

Research output: Contribution to journalArticleResearchpeer-review

JNK Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Reactive Oxygen Species
5 Citations (Scopus)
Oxidative stress
Oxidative Stress
Wounds and Injuries