Projects per year
Personal profile
Area of Expertise
My area of expertise is in translational aging research. I am the Co-I of Health & Aging Brain among Latino Elders (HABLE) study (R01AG054073) and the Director of the Clinical and Outreach cores for this study. I have spent a great deal of time studying factors related to cognitive loss among Mexican-Americans with a specific emphasis on the link between depression and cognition. I have developed and cross-validated a depressive endophenotype (DepE) of cognitive aging across multiple national and international cohorts. This work has been translated into a proof of concept clinical trial (The DEMO trial). The DEMO trial utilizes a precision medicine approach to identify those individuals more likely to benefit from antidepressant treatment for prevention of memory loss and potentially Alzheimer’s disease.
Education/Academic qualification
BSW in Psychology, Louisiana State University
MSW, Louisiana State University
PhD in Social Work, University of Texas at Arlington
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Projects
An Alzheimer's Blood Test for Primary Care
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
1/06/18 → 31/05/21
Project: Research
A Blood Test for Screening into Alzheimer's Prevention Trials
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican Americans
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
1/09/17 → 31/05/22
Project: Research
A Pro-Inflammatory Endophenotype to Predict Treatment Response to NSAID Therapy in AD
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
1/09/16 → 31/03/21
Project: Research
Amyloid Burden among Mexican Americans
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
30/09/18 → 31/08/19
Project: Research
Research Output
Cardiovascular risk factors in Mexico and the United States: a comparative cross-sectional study between the HABLE and MHAS participants
Vintimilla, R., Reyes, M., Johnson, L., Hall, J. & O'Bryant, S., 1 Jan 2020, In : Gaceta medica de Mexico. 156, 1, p. 17-21 5 p.Research output: Contribution to journal › Article
Open Access
Combining Select Blood-Based Biomarkers with Neuropsychological Assessment to Detect Mild Cognitive Impairment among Mexican Americans
Petersen, M., Hall, J., Parsons, T., Johnson, L. & O'Bryant, S., 2020, In : Journal of Alzheimer's Disease. 75, 3, p. 739-750 12 p.Research output: Contribution to journal › Article
Factores de riesgo cardiovascular en Estados Unidos y México: Comparación de los estudios hable y enasem
Research output: Contribution to journal › Article
Open Access
The impact of comorbid depression-diabetes on proteomic outcomes among community-dwelling Mexican Americans with mild cognitive impairment
Johnson, L. A., Zhang, F., Large, S., Hall, J. & O'bryant, S. E., 1 Jan 2020, In : International Psychogeriatrics. 32, 1, p. 17-23 7 p.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
A proteomic signature for dementia with Lewy bodies
O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.Research output: Contribution to journal › Article
Open Access
3
Scopus
citations