Projects per year
Personal profile
Area of Expertise
My area of expertise is in translational aging research. I am the Co-I of Health & Aging Brain among Latino Elders (HABLE) study (R01AG054073) and the Director of the Clinical and Outreach cores for this study. I have spent a great deal of time studying factors related to cognitive loss among Mexican-Americans with a specific emphasis on the link between depression and cognition. I have developed and cross-validated a depressive endophenotype (DepE) of cognitive aging across multiple national and international cohorts. This work has been translated into a proof of concept clinical trial (The DEMO trial). The DEMO trial utilizes a precision medicine approach to identify those individuals more likely to benefit from antidepressant treatment for prevention of memory loss and potentially Alzheimer’s disease.
Education/Academic qualification
BSW in Psychology, Louisiana State University
MSW, Louisiana State University
PhD in Social Work, University of Texas at Arlington
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L., O'BRYANT, S., JOHNSON, L., RISSMAN, R. & TOGA, A.
30/09/18 → 30/04/22
Project: Research
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A Blood Test for Screening into Alzheimer's Prevention Trials
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
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Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican Americans
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
1/09/17 → 31/05/22
Project: Research
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Amyloid Burden among Mexican Americans
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
30/09/18 → 31/08/19
Project: Research
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An Alzheimer's Blood Test for Primary Care
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
1/06/18 → 31/05/21
Project: Research
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A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, 2021, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
O'Bryant, S. E., Zhang, F., Petersen, M., Johnson, L., Hall, J. & Rissman, R. A., 2021, In: Journal of Alzheimer's Disease. 81, 2, p. 557-568 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Recursive Support Vector Machine Biomarker Selection for Alzheimer's Disease
Zhang, F., Petersen, M., Johnson, L., Hall, J. & O'Bryant, S. E., 2021, In: Journal of Alzheimer's Disease. 79, 4, p. 1691-1700 10 p.Research output: Contribution to journal › Article › peer-review
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The health & aging brain among latino elders (Hable) study methods and participant characteristics
O’bryant, S. E., Johnson, L. A., Barber, R. C., Braskie, M. N., Christian, B., Hall, J. R., Hazra, N., King, K., Kothapalli, D., Large, S., Mason, D., Matsiyevskiy, E., McColl, R., Nandy, R. R., Palmer, R., Petersen, M., Philips, N., Rissman, R. A., Shi, Y., Toga, A. W. & 4 others, , 2021, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 13, 1, e12202.Research output: Contribution to journal › Article › peer-review
Open Access -
Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer's Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study
Hall, J., Johnson, L. A., Zhang, F., Petersen, M., Toga, A. W., Shi, Y., Mason, D., Rissman, R. A., Yaffe, K. & O'Bryant, S. E., 2021, (Accepted/In press) In: Dementia and Geriatric Cognitive Disorders.Research output: Contribution to journal › Article › peer-review