Projects per year
Personal profile
Area of Expertise
My area of expertise is in translational aging research. I am the Co-I of Health & Aging Brain among Latino Elders (HABLE) study (R01AG054073) and the Director of the Clinical and Outreach cores for this study. I have spent a great deal of time studying factors related to cognitive loss among Mexican-Americans with a specific emphasis on the link between depression and cognition. I have developed and cross-validated a depressive endophenotype (DepE) of cognitive aging across multiple national and international cohorts. This work has been translated into a proof of concept clinical trial (The DEMO trial). The DEMO trial utilizes a precision medicine approach to identify those individuals more likely to benefit from antidepressant treatment for prevention of memory loss and potentially Alzheimer’s disease.
Education/Academic qualification
BSW in Psychology, Louisiana State University
MSW, Louisiana State University
PhD in Social Work, University of Texas at Arlington
Fingerprint
Dive into the research topics where Leigh Johnson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
The Health & Aging Brain Study - Health Disparities (HABS-HD)
O'Bryant, S., Johnson, L., TOGA, A., YAFFE, K. & RISSMAN, R.
30/09/22 → 31/08/23
Project: Research
-
Health and Aging Brain among Latino Elders (HABLE-AT(N)) Study
RISSMAN, R., TOGA, A., RISSMAN, R., O'BRYANT, S., JOHNSON, L., JOHNSON, L., O'Bryant, S. & Johnson, L.
1/08/20 → 30/04/23
Project: Research
-
Genetic Architecture of Alzheimer’s disease Proteinopathies
Johnson, L., CRUCHAGA, C., CRUCHAGA, C. & KAMBOH, I.
15/04/21 → 28/02/23
Project: Research
-
Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L., O'BRYANT, S., JOHNSON, L., RISSMAN, R. & TOGA, A.
30/09/18 → 30/04/22
Project: Research
-
Amyloid Burden among Mexican Americans
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
30/09/18 → 31/08/19
Project: Research
-
Medical comorbidities and ethnicity impact plasma Alzheimer's disease biomarkers: Important considerations for clinical trials and practice
for the HABS-HD Study Team, Jan 2023, In: Alzheimer's and Dementia. 19, 1, p. 36-43 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Plasma Biomarkers of Alzheimer's Disease Are Associated with Physical Functioning Outcomes Among Cognitively Normal Adults in the Multiethnic HABS-HD Cohort
HABS-HD Study Team, 26 Jan 2023, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 78, 1, p. 9-15 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, Jan 2022, In: Alzheimer's and Dementia. 18, 1, p. 77-87 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Analysis of a precision medicine approach to treating Parkinson's disease: Analysis of the DATATOP study
O'Bryant, S. E., Petersen, M., Zhang, F., Johnson, L., Mason, D. & Hall, J., Jan 2022, In: Parkinsonism and Related Disorders. 94, p. 15-21 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
APOEε4 Genotype Is Related to Brain Amyloid Among Mexican Americans in the HABS-HD Study
The HABS-HD Study Team, 15 Jun 2022, In: Frontiers in Neurology. 13, 834685.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations