Projects per year
Personal profile
Area of Expertise
My area of expertise is in translational aging research. I am the Co-I of Health & Aging Brain among Latino Elders (HABLE) study (R01AG054073) and the Director of the Clinical and Outreach cores for this study. I have spent a great deal of time studying factors related to cognitive loss among Mexican-Americans with a specific emphasis on the link between depression and cognition. I have developed and cross-validated a depressive endophenotype (DepE) of cognitive aging across multiple national and international cohorts. This work has been translated into a proof of concept clinical trial (The DEMO trial). The DEMO trial utilizes a precision medicine approach to identify those individuals more likely to benefit from antidepressant treatment for prevention of memory loss and potentially Alzheimer’s disease.
Education/Academic qualification
BSW in Psychology, Louisiana State University
MSW, Louisiana State University
PhD in Social Work, University of Texas at Arlington
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L., O'BRYANT, S., JOHNSON, L., RISSMAN, R. & TOGA, A.
30/09/18 → 30/04/22
Project: Research
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A Blood Test for Screening into Alzheimer's Prevention Trials
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
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Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican Americans
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
1/09/17 → 31/05/22
Project: Research
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Amyloid Burden among Mexican Americans
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
30/09/18 → 31/08/19
Project: Research
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An Alzheimer's Blood Test for Primary Care
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
1/06/18 → 31/05/21
Project: Research
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A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, 2021, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
O'Bryant, S. E., Zhang, F., Petersen, M., Johnson, L., Hall, J. & Rissman, R. A., 2021, In: Journal of Alzheimer's Disease. 81, 2, p. 557-568 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Recursive Support Vector Machine Biomarker Selection for Alzheimer's Disease
Zhang, F., Petersen, M., Johnson, L., Hall, J. & O'Bryant, S. E., 2021, In: Journal of Alzheimer's Disease. 79, 4, p. 1691-1700 10 p.Research output: Contribution to journal › Article › peer-review
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Cardiovascular Risk Factors, Cognitive Dysfunction, and Mild Cognitive Impairment
Vintimilla, R., Balasubramanian, K., Hall, J., Johnson, L. & O'Bryant, S., Sep 2020, In: Dementia and Geriatric Cognitive Disorders Extra. 10, 3, p. 154-162 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cardiovascular risk factors in Mexico and the United States: a comparative cross-sectional study between the HABLE and MHAS participants
Vintimilla, R., Reyes, M., Johnson, L., Hall, J. & O'Bryant, S., 2020, In: Gaceta medica de Mexico. 156, 1, p. 17-21 5 p.Research output: Contribution to journal › Article › peer-review
Open Access