Projects per year
Personal profile
Area of Expertise
My area of expertise is in translational aging research. I am the Co-I of Health & Aging Brain among Latino Elders (HABLE) study (R01AG054073) and the Director of the Clinical and Outreach cores for this study. I have spent a great deal of time studying factors related to cognitive loss among Mexican-Americans with a specific emphasis on the link between depression and cognition. I have developed and cross-validated a depressive endophenotype (DepE) of cognitive aging across multiple national and international cohorts. This work has been translated into a proof of concept clinical trial (The DEMO trial). The DEMO trial utilizes a precision medicine approach to identify those individuals more likely to benefit from antidepressant treatment for prevention of memory loss and potentially Alzheimer’s disease.
Education/Academic qualification
BSW in Psychology, Louisiana State University
MSW, Louisiana State University
PhD in Social Work, University of Texas at Arlington
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Health and Aging Brain among Latino Elders (HABLE-AT(N)) Study
RISSMAN, R., TOGA, A., RISSMAN, R., O'BRYANT, S., JOHNSON, L., JOHNSON, L., O'Bryant, S. & Johnson, L.
1/08/20 → 30/04/23
Project: Research
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Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L., O'BRYANT, S., JOHNSON, L., RISSMAN, R. & TOGA, A.
30/09/18 → 30/04/22
Project: Research
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Amyloid Burden among Mexican Americans
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
30/09/18 → 31/08/19
Project: Research
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An Alzheimer's Blood Test for Primary Care
O'Bryant, S., Hall, J., Johnson, L. & Nandy, R.
NIA: National Institute on Aging
1/06/18 → 31/05/21
Project: Research
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A Blood Test for Screening into Alzheimer's Prevention Trials
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
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A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, Jan 2022, In: Alzheimer's and Dementia. 18, 1, p. 77-87 11 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Analysis of a precision medicine approach to treating Parkinson's disease: Analysis of the DATATOP study
O'Bryant, S. E., Petersen, M., Zhang, F., Johnson, L., Mason, D. & Hall, J., Jan 2022, In: Parkinsonism and Related Disorders. 94, p. 15-21 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
APOEε4 Genotype Is Related to Brain Amyloid Among Mexican Americans in the HABS-HD Study
The HABS-HD Study Team, 15 Jun 2022, In: Frontiers in Neurology. 13, 834685.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Characterizing Plasma Biomarkers of Alzheimer's in a Diverse Community-Based Cohort: A Cross-Sectional Study of the HAB-HD Cohort
The Health and Aging Brain Study (HABS-HD) Study Team, 18 Aug 2022, In: Frontiers in Neurology. 13, 871947.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study
for the HABLE Study Team, Feb 2022, In: Alzheimer's and Dementia. 18, 2, p. 240-250 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations