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Pharmacology, Toxicology and Pharmaceutical Science
Aldehyde Oxidase
10%
Allosteric Modulator
100%
Amine
5%
Anxiolytic
5%
Benign Childhood Epilepsy
9%
Binding Site
7%
Carboxamide
15%
Clinical Trial
9%
Competitive Antagonist
9%
Cytochrome P450
7%
Diseases
9%
G Protein Coupled Receptor
7%
Glutamate Receptor
15%
Metabotropic Receptor
38%
Metabotropic Receptor 5
14%
Mouse Model
12%
Neuropeptide Y4 Receptor
7%
Parkinson's Disease
6%
Pharmacokinetics
10%
Picolinamide
8%
Polo Like Kinase 1
7%
Positive Allosteric Modulator
26%
Potassium Channel
10%
Protein Binding
9%
Pyridine
12%
Pyrimidine
7%
Quinidine
5%
Rat
31%
Receptor
22%
Sodium
7%
Somatomedin C Receptor
7%
Structure Activity Relationship
34%
Toxicology
5%
Keyphrases
Asymmetric Alkylation
7%
Automated Patch Clamp
6%
Benzimidazole Synthesis
7%
Chemotype
15%
Clinically Significant
5%
Disubstituted
6%
Epilepsy of Infancy with Migrating Focal Seizures (EIMFS)
10%
Epilepsy Treatment
5%
Ether
7%
Gain-of-function mutation
6%
Glutamate Receptors
8%
High-throughput Screen
7%
Highly Selective
8%
Hit Optimization
5%
Ion Channels
5%
KCNT1
7%
KCNT1 Gene
5%
Medium-sized Rings
7%
Metabotropic Glutamate Receptor
8%
Metabotropic Glutamate Receptor 3
7%
Metabotropic Glutamate Receptor 5 (mGluR5)
28%
MGlu
10%
MGlu2
5%
MGlu3
7%
MGlu5 NAM
8%
Negative Allosteric Modulator
41%
New Analogs
8%
Patch Clamp Assay
5%
Patent Review
7%
Penetrant
8%
Polo-like Kinase 1
7%
Positive Allosteric Modulator
9%
Potassium Channel
18%
Potent Inhibitor
5%
Pyrimidin
10%
Relationship Research
15%
Ring-closing Metathesis
5%
Small Molecule Inhibitors
14%
Small Molecules
10%
Sodium-activated Potassium Channel
8%
Structure-activity Relationship
20%
Tool Compound
10%
Total Synthesis
7%
Whole Cell
5%
Xanthine
7%
Biochemistry, Genetics and Molecular Biology
Aldehyde Oxidase
7%
Allosteric Site
7%
Automated Patch Clamp
7%
C-Terminus
7%
Colon Mucosa
7%
Cooperation
7%
G Protein Coupled Receptor
11%
Gain of Function Mutation
7%
High Throughput Screening
10%
Infancy
13%
KCNT1
8%
Metabotropic Glutamate Receptor
16%
Metabotropic Glutamate Receptor 5
7%
Metabotropic Receptor
16%
Mutagenesis
7%
N-Terminus
7%
Neuropeptide
7%
Potassium Channel
20%
Quantitative Structure Activity Relation
7%
Quantitative Structure-Activity Relationship
7%
Satiety
7%
Small Molecule
21%
Structure Activity Relation
10%
Structure Activity Relationship
11%
Tranquilizing Activity
5%
Whole Cell
7%
Wild Type
6%