Projects per year
Personal profile
Area of Expertise
The Emmitte laboratory employs multiple types of medicinal chemistry strategies to design, synthesize, and optimize biologically active small molecules to serve as in vivo probes, drug discovery leads, and optimized preclinical compounds. Research in the Emmitte laboratory is highly collaborative and works on several different types of drug target classes across several therapeutic areas.
Education/Academic qualification
BS in Chemistry, Texas A & M University
PhD in Organic Chemistry, University of North Carolina at Chapel Hill
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Dive into the research topics where Kyle Emmitte is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 13 Finished
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Discovery of small molecule activators of the Slack potassium channel for use as cell-based probes for the study of fragile X syndrome
Emmitte, K. & WEAVER, D.
National Institute of Mental Health
1/12/20 → 31/10/21
Project: Research
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Discovery of small molecule activators of the Slack potassium channel for use as cell-based probes for the study of fragile X syndrome
WEAVER, D., WEAVER, C., EMMITTE, K. & Emmitte, K.
1/12/20 → 31/10/22
Project: Research
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Slack Potassium Channel Inhibitors for the Treatment of Childhood Epilepsies
Emmitte, K., WEAVER, D., Emmitte, K., EMMITTE, K., Emmitte, K. & WEAVER, C.
1/01/20 → 31/12/22
Project: Research
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Slack Potassium Channel Inhibitors for the Treatment of Childhood Epilepsies
Emmitte, K., WEAVER, D., WEAVER, D. & EMMITTE, K.
National Institute of Neurological Disorders and Stroke
15/12/18 → 31/12/21
Project: Research
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Slack Potassium Channel Inhibitors for the Treatment of Childhood Epilepsies
15/12/18 → 30/11/19
Project: Research
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Small-molecule inhibitors of Slack potassium channels as potential therapeutics for childhood epilepsies
Qunies, AA. M. & Emmitte, K. A., Mar 2022, In: Pharmaceutical Patent Analyst. 11, 2, p. 45-56 12 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Structure–activity relationship studies in a new series of 2-amino-N-phenylacetamide inhibitors of Slack potassium channels
Qunies, A. M., Mishra, N. M., Spitznagel, B. D., Du, Y., Acuña, V. S., David Weaver, C. & Emmitte, K. A., 15 Nov 2022, In: Bioorganic and Medicinal Chemistry Letters. 76, 129013.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Highly Selective Y4Receptor Antagonist Binds in an Allosteric Binding Pocket
Schüß, C., Vu, O., Schubert, M., Du, Y., Mishra, N. M., Tough, I. R., Stichel, J., Weaver, C. D., Emmitte, K. A., Cox, H. M., Meiler, J. & Beck-Sickinger, A. G., 11 Mar 2021, In: Journal of Medicinal Chemistry. 64, 5, p. 2801-2814 14 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Negative allosteric modulators of group II metabotropic glutamate receptors: A patent review (2015–present)
Qunies, A. M. & Emmitte, K. A., 2021, In: Expert Opinion on Therapeutic Patents. 31, 8, p. 687-708 22 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons
Spitznagel, B. D., Mishra, N. M., Qunies, AA. M., Prael, F. J., Du, Y., Kozek, K. A., Lazarenko, R. M., Denton, J. S., Emmitte, K. A. & Weaver, C. D., 4 Nov 2020, In: ACS Chemical Neuroscience. 11, 21, p. 3658-3671 14 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations