Projects per year
Personal profile
Area of Expertise
My laboratory focuses on the mechanisms underlying regulation of aging on neurogenesis after stroke. Specifically, I will explore the roles of molecular pathways in neurogenesis during aging and in the aged brain after stroke. I am also interested in whether damaged brain tissue in the chronic phase after stroke can be repaired through a stem cell-based tissue engineering approach. In addition, I investigate whether hippocampal neurogenesis contributes to the neuropathology and cognitive impairment of Alzheimer's disease and whether modulating this process could provide a mechanistic and therapeutic approach to the disease.
Education/Academic qualification
PhD in Molecular Biology, Beijing University
MD , Wenzhou Medical University
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Collaborations and top research areas from the last five years
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Projects
- 17 Finished
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Effects of Aging on Blood Vessels in the Cerebellar Vermis
Jin, K. (PI), Forster, M. (CoI) & Sumien, N. (CoI)
NIA: National Institute on Aging
1/04/19 → 31/01/22
Project: Research
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Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S. (PI), Liu, R. (CoI), Sumien, N. (CoI) & Jin, K. (CoI)
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
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Post Stroke Cognitive Impairme
Yang, S. (PI), Liu, R. (CoI), Sumien, N. (CoI) & Jin, K. (CoI)
NINDS: Neurological Disorders & Stroke
1/02/19 → 30/06/24
Project: Research
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The Effect of Young and Aged Serum Exosomes on Ischemic Stroke Outcome (For: Hongxia Zhang)
Jin, K. (PI)
1/07/18 → 30/06/20
Project: Research
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Direct Reprogramming of Reactive Astrocytes after Stroke
Jin, K. (PI) & Uteshev, V. (CoI)
William & Ella Owens Med Research Foun
1/03/18 → 28/02/20
Project: Research
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In situ detection of neuronal DNA strand breaks using the Klenow fragment of DNA polymerase I reveals different mechanisms of neuron death after global cerebral ischemia
Jin, K., Chen, J., Nagayama, T., Chen, M., Sinclair, J., Graham, S. H. & Simon, R. P., 1999, In: Journal of Neurochemistry. 72, 3, p. 1204-1214 11 p.Research output: Contribution to journal › Article › peer-review
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Evidence of brain tumor stem progenitor-like cells with low proliferative capacity in human benign pituitary adenoma
Chen, L., Ye, H., Wang, X., Tang, X., Mao, Y., Zhao, Y., Wu, Z., Mao, X. O., Xie, L., Jin, K. & Yao, Y., 10 Jul 2014, In: Cancer Letters. 349, 1, p. 61-66 6 p.Research output: Contribution to journal › Article › peer-review
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Bulbocavernosus reflex and pudendal nerve somatosensory-evoked potentials responses in female patients with nerve system diseases
Niu, X., Shao, B., Ni, P., Wang, X., Chen, X., Zhu, B., Wang, Z., Teng, H. & Jin, K., Jun 2010, In: Journal of Clinical Neurophysiology. 27, 3, p. 207-211 5 p.Research output: Contribution to journal › Article › peer-review
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Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo
Wang, X., Mao, X., Xie, L., Greenberg, D. A. & Jin, K., Oct 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 10, p. 1644-1654 11 p.Research output: Contribution to journal › Article › peer-review
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Electrophysiological neurodifferentiation of subventricular zone-derived precursor cells following stroke
Lai, B., Mao, X. O., Xie, L., Jin, K. & Greenberg, D. A., 19 Sep 2008, In: Neuroscience letters. 442, 3, p. 305-308 4 p.Research output: Contribution to journal › Article › peer-review