Projects per year
Personal profile
Area of Expertise
My laboratory focuses on the mechanisms underlying regulation of aging on neurogenesis after stroke. Specifically, I will explore the roles of molecular pathways in neurogenesis during aging and in the aged brain after stroke. I am also interested in whether damaged brain tissue in the chronic phase after stroke can be repaired through a stem cell-based tissue engineering approach. In addition, I investigate whether hippocampal neurogenesis contributes to the neuropathology and cognitive impairment of Alzheimer's disease and whether modulating this process could provide a mechanistic and therapeutic approach to the disease.
Education/Academic qualification
PhD in Molecular Biology, Beijing University
MD , Wenzhou Medical University
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Projects
Effects of Aging on Blood Vessels in the Cerebellar Vermis
Jin, K., Forster, M. & Sumien, N.
NIA: National Institute on Aging
1/04/19 → 31/01/21
Project: Research
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
The Effect of Young and Aged Serum Exosomes on Ischemic Stroke Outcome (For: Hongxia Zhang)
1/07/18 → 30/06/20
Project: Research
Direct Reprogramming of Reactive Astrocytes after Stroke
William & Ella Owens Med Research Foun
1/03/18 → 28/02/19
Project: Research
Research Output
Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
Zhang, L. Y., Pan, J., Mamtilahun, M., Zhu, Y., Wang, L., Venkatesh, A., Shi, R., Tu, X., Jin, K., Wang, Y., Zhang, Z. & Yang, G. Y., 1 Jan 2020, In : Theranostics. 10, 1, p. 74-90 17 p.Research output: Contribution to journal › Article
Open Access
New measures for COVID-19 response: a lesson from the Wenzhou experience
Ruan, L., Wen, M., Zeng, Q., Chen, C., Huang, S., Yang, S., Yang, J., Wang, J., Hu, Y., Ding, S., Zhang, Y., Zhang, H., Feng, Y., Jin, K. & ZhuGe, Q., 3 Apr 2020, (Accepted/In press) In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
Peripheral circulating exosomal miRNAs potentially contribute to the regulation of molecular signaling networks in aging
Zhang, H. & Jin, K., 2 Mar 2020, In : International journal of molecular sciences. 21, 6, 1908.Research output: Contribution to journal › Article
Open Access
2
Scopus
citations
Transplantation of ACE2- Mesenchymal stem cells improves the outcome of patients with covid-19 pneumonia
Leng, Z., Zhu, R., Hou, W., Feng, Y., Yang, Y., Han, Q., Shan, G., Meng, F., Du, D., Wang, S., Fan, J., Wang, W., Deng, L., Shi, H., Li, H., Hu, Z., Zhang, F., Gao, J., Liu, H., Li, X. & 18 others, , 1 Jan 2020, In : Aging and Disease. 11, 2, p. 216-228 13 p.Research output: Contribution to journal › Article
Open Access
AMPK signaling regulates the age-related decline of hippocampal neurogenesis
Wang, B. Z., Yang, J. J., Zhang, H., Smith, C. A. & Jin, K., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 1058-1074 17 p.Research output: Contribution to journal › Article
Open Access
2
Scopus
citations