Projects per year
Personal profile
Area of Expertise
My laboratory focuses on the mechanisms underlying regulation of aging on neurogenesis after stroke. Specifically, I will explore the roles of molecular pathways in neurogenesis during aging and in the aged brain after stroke. I am also interested in whether damaged brain tissue in the chronic phase after stroke can be repaired through a stem cell-based tissue engineering approach. In addition, I investigate whether hippocampal neurogenesis contributes to the neuropathology and cognitive impairment of Alzheimer's disease and whether modulating this process could provide a mechanistic and therapeutic approach to the disease.
Education/Academic qualification
PhD in Molecular Biology, Beijing University
MD , Wenzhou Medical University
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Medicine & Life Sciences
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Ischemia
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Middle Cerebral Artery Infarction
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2011 2024
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
The Effect of Young and Aged Serum Exosomes on Ischemic Stroke Outcome (For: Hongxia Zhang)
1/07/18 → 30/06/20
Project: Research
Neuroglobin: Cell Membrane and Neuroprotection
NINDS: Neurological Disorders & Stroke
1/07/14 → 31/05/19
Project: Research
Direct Reprogramming of Reactive Astrocytes after Stroke
William & Ella Owens Med Research Foun
1/03/18 → 28/02/19
Project: Research
Research Output 1989 2019
Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats
Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., 1 Jan 2019, (Accepted/In press) In : Neurochemistry International.Research output: Contribution to journal › Article › Research › peer-review
Autophagy
Stroke
Middle Cerebral Artery Infarction
Young Adult
Up-Regulation
Intracranial atherosclerotic disease
Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., 1 Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.Research output: Contribution to journal › Article › Research › peer-review
Intracranial Arteriosclerosis
Stroke
Therapeutics
Recurrence
Risk Management
Remote ischemic conditioning for stroke: clinical data, challenges, and future directions
Zhao, W., Li, S., Ren, C., Meng, R., Jin, K. & Ji, X., 1 Jan 2019, In : Annals of Clinical and Translational Neurology. 6, 1, p. 186-196 11 p.Research output: Contribution to journal › Review article › Research › peer-review
Stroke
Brain
Conditioning (Psychology)
Direction compound
Cerebral Small Vessel Diseases
Ac-YVAD-CMK inhibits pyroptosis and improves functional outcome after intracerebral hemorrhage
Lin, X., Ye, H., Siaw-Debrah, F., Pan, S., He, Z., Ni, H., Xu, Z., Jin, K., Zhuge, Q. & Huang, L., 1 Jan 2018, In : BioMed Research International. 2018, 3706047.Research output: Contribution to journal › Article › Research › peer-review
Cerebral Hemorrhage
Cell death
Chemical activation
Cell Death
Inflammasomes
1
Citation
(Scopus)
Aging health and R & D for healthy longevity must be included into the WHO work program
Stambler, I., Jin, K., Lederman, S., Barzilai, N., Jay Olshansky, S., Omokaro, E., Barratt, J., Anisimov, V. N., Rattan, S., Yang, S., Forster, M. J. & Byles, J., 1 Apr 2018, In : Aging and Disease. 9, 2, p. 331-333 3 p.Research output: Contribution to journal › Editorial › Research
Health