Projects per year
Personal profile
Area of Expertise
My laboratory focuses on the mechanisms underlying regulation of aging on neurogenesis after stroke. Specifically, I will explore the roles of molecular pathways in neurogenesis during aging and in the aged brain after stroke. I am also interested in whether damaged brain tissue in the chronic phase after stroke can be repaired through a stem cell-based tissue engineering approach. In addition, I investigate whether hippocampal neurogenesis contributes to the neuropathology and cognitive impairment of Alzheimer's disease and whether modulating this process could provide a mechanistic and therapeutic approach to the disease.
Education/Academic qualification
PhD in Molecular Biology, Beijing University
MD , Wenzhou Medical University
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2011 2024
Effects of Aging on Blood Vessels in the Cerebellar Vermis
Jin, K., Forster, M. & Sumien, N.
NIA: National Institute on Aging
1/04/19 → 31/01/21
Project: Research
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
The Effect of Young and Aged Serum Exosomes on Ischemic Stroke Outcome (For: Hongxia Zhang)
1/07/18 → 30/06/20
Project: Research
Direct Reprogramming of Reactive Astrocytes after Stroke
William & Ella Owens Med Research Foun
1/03/18 → 28/02/19
Project: Research
Research Output 1989 2019
Exosomes derived from bone mesenchymal stem cells ameliorate early inflammatory responses following traumatic brain injury
Ni, H., Yang, S., Siaw-Debrah, F., Hu, J., Wu, K., He, Z., Yang, J., Pan, S., Lin, X., Ye, H., Xu, Z., Wang, F., Jin, K., Zhuge, Q. & Huang, L., 1 Jan 2019, In : Frontiers in Neuroscience. 13, JAN, 14.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Exosomes
Mesenchymal Stromal Cells
Bone and Bones
Microglia
Macrophages
Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats
Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., 1 Jul 2019, In : Neurochemistry International. 127, p. 64-72 9 p.Research output: Contribution to journal › Article › Research › peer-review
Autophagy
Stroke
Middle Cerebral Artery Infarction
Young Adult
Up-Regulation
Intracranial atherosclerotic disease
Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., 1 Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.Research output: Contribution to journal › Article › Research › peer-review
Intracranial Arteriosclerosis
Stroke
Therapeutics
Recurrence
Risk Management
Remote ischemic conditioning for stroke: clinical data, challenges, and future directions
Zhao, W., Li, S., Ren, C., Meng, R., Jin, K. & Ji, X., 1 Jan 2019, In : Annals of Clinical and Translational Neurology. 6, 1, p. 186-196 11 p.Research output: Contribution to journal › Review article › Research › peer-review
Stroke
Brain
Conditioning (Psychology)
Direction compound
Cerebral Small Vessel Diseases
The effect of age, sex and strains on the performance and outcome in animal models of stroke
Zhang, H., Lin, S., Chen, X., Gu, L., Zhu, X., Zhang, Y., Reyes, K., Wang, B. & Jin, K., 1 Jul 2019, In : Neurochemistry International. 127, p. 2-11 10 p.Research output: Contribution to journal › Review article › Research › peer-review
Animal Models
Stroke
Rodentia
Cerebrovascular Circulation
Brain Infarction