Projects per year
Personal profile
Area of Expertise
My laboratory focuses on the mechanisms underlying regulation of aging on neurogenesis after stroke. Specifically, I will explore the roles of molecular pathways in neurogenesis during aging and in the aged brain after stroke. I am also interested in whether damaged brain tissue in the chronic phase after stroke can be repaired through a stem cell-based tissue engineering approach. In addition, I investigate whether hippocampal neurogenesis contributes to the neuropathology and cognitive impairment of Alzheimer's disease and whether modulating this process could provide a mechanistic and therapeutic approach to the disease.
Education/Academic qualification
PhD in Molecular Biology, Beijing University
MD , Wenzhou Medical University
Fingerprint Dive into the research topics where Kunlin Jin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 18 Similar Profiles
Neurogenesis
Medicine & Life Sciences
Brain
Medicine & Life Sciences
Stroke
Medicine & Life Sciences
Brain Ischemia
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Ischemia
Medicine & Life Sciences
Middle Cerebral Artery Infarction
Medicine & Life Sciences
Vascular Endothelial Growth Factor A
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2011 2024
Effects of Aging on Blood Vessels in the Cerebellar Vermis
Jin, K., Forster, M. & Sumien, N.
NIA: National Institute on Aging
1/04/19 → 31/01/21
Project: Research
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
The Effect of Young and Aged Serum Exosomes on Ischemic Stroke Outcome (For: Hongxia Zhang)
1/07/18 → 30/06/20
Project: Research
Direct Reprogramming of Reactive Astrocytes after Stroke
William & Ella Owens Med Research Foun
1/03/18 → 28/02/19
Project: Research
Research Output 1989 2019
AMPK signaling regulates the age-related decline of hippocampal neurogenesis
Wang, B. Z., Yang, J. J., Zhang, H., Smith, C. A. & Jin, K., 1 Jan 2019, In : Aging and Disease. 10, 5, p. 1058-1074 17 p.Research output: Contribution to journal › Article
Open Access
AMP-Activated Protein Kinases
Neurogenesis
Hippocampus
Brain
Intrinsic Factor
8
Citations
(Scopus)
Exosomes derived from bone mesenchymal stem cells ameliorate early inflammatory responses following traumatic brain injury
Ni, H., Yang, S., Siaw-Debrah, F., Hu, J., Wu, K., He, Z., Yang, J., Pan, S., Lin, X., Ye, H., Xu, Z., Wang, F., Jin, K., Zhuge, Q. & Huang, L., 1 Jan 2019, In : Frontiers in Neuroscience. 13, JAN, 14.Research output: Contribution to journal › Article
Open Access
Exosomes
Mesenchymal Stromal Cells
Bone and Bones
Microglia
Macrophages
Inhibition of miR-497 improves functional outcome after ischemic stroke by enhancing neuronal autophagy in young and aged rats
Chen, X., Lin, S., Gu, L., Zhu, X., Zhang, Y., Zhang, H., Shao, B., Zhuge, Q. & Jin, K., Jul 2019, In : Neurochemistry International. 127, p. 64-72 9 p.Research output: Contribution to journal › Article
Autophagy
Stroke
Middle Cerebral Artery Infarction
Young Adult
Up-Regulation
Intracranial atherosclerotic disease
Wang, Y., Meng, R., Liu, G., Cao, C., Chen, F., Jin, K., Ji, X. & Cao, G., Apr 2019, In : Neurobiology of Disease. 124, p. 118-132 15 p.Research output: Contribution to journal › Article
Intracranial Arteriosclerosis
Stroke
Therapeutics
Recurrence
Risk Management
Models of poststroke depression and assessments of core depressive symptoms in rodents: How to choose?
Tao, X., Yang, W., Zhu, S., Que, R., Liu, C., Fan, T., Wang, J., Mo, D., Zhang, Z., Tan, J., Jin, K., Yenarih, M. A., Song, T. & Wang, Q., Dec 2019, In : Experimental Neurology. 322, 113060.Research output: Contribution to journal › Review article
Rodentia
Stroke
Depression
Animal Models
Anhedonia