Projects per year
Personal profile
Area of Expertise
I am currently the PI of a federally-funded grant from the National Heart, Lung, and Blood Institute and a private grant from the Lupus Research Alliance. The federal grant will investigate the regulation of inflammation in the kidney that, if accumulated and left unchecked, can lead to hypertension and renal injury. The private grant will test the efficacy of a cholinergic agonist as an anti-inflammatory therapy in lupus mice and determine whether this drug has positive outcomes on behavior. Work in my lab will include integrative physiological approaches complimented with molecular, cellular, and immunological techniques. A goal of the lab is to take what is learned in the animal model of lupus hypertension and translate it into human studies that could benefit both lupus and hypertensive populations.
Education/Academic qualification
MS in Physiology, LSU Health Science Center
PhD in Physiology, LSU Health Science Center
MS in Applied Physics, Purdue University
BS in Physics, Southern University
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Network
Projects
- 13 Finished
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Control of Renal Inflammation in Hypertension
MATHIS, K. W. & Mathis, K.
National Heart, Lung, and Blood Institute
14/05/21 → 30/04/23
Project: Research
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Targeting Nicotinic Receptors to Reduce Inflammation Associated with SLE
Mathis, K. & Uteshev, V.
1/03/18 → 28/02/21
Project: Research
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Neuroimmune Mechanisms Involved in the Pathogenesis of Hypertension and Renal Injury
MATHIS, K. & Mathis, K.
National Heart, Lung, and Blood Institute
1/01/18 → 31/12/22
Project: Research
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Neuroimmune Mechanisms Involved in the Pathogenesis of Hypertension and Renal Injury
Mathis, K. & MATHIS, K. W.
National Heart, Lung, and Blood Institute
1/01/18 → 31/12/21
Project: Research
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Neuroimmune Mechanisms Involved in the Pathogenesis of Hypertension and Renal Injury
NHLBI: Nat Heart, Lung & Blood Institute
1/01/18 → 31/12/22
Project: Research
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Editorial: Renal injury and the brain
Shimoura, C. G., Wallace, K. & Mathis, K. W., 4 Jan 2023, In: Frontiers in Medicine. 9, 1100487.Research output: Contribution to journal › Editorial
Open Access -
Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells
Chaudhari, S., Shotorbani, P. Y., Tao, Y., Kasetti, R., Zode, G., Mathis, K. W. & Ma, R., Jul 2022, In: American Journal of Physiology - Cell Physiology. 323, 1, p. C226-C235Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Renal TLR-7/TNF-α pathway as a potential female-specific mechanism in the pathogenesis of autoimmune-induced hypertension
Chaudhari, S., D'Souza, B. M., Morales, J. Y., Young-Stubbs, C. M., Shimoura, C. G., Ma, R. & Mathis, K. W., 1 Dec 2022, In: American journal of physiology. Heart and circulatory physiology. 323, 6, p. H1331-H1342Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Should Renal Inflammation Be Targeted While Treating Hypertension?
Chaudhari, S., Pham, G. S., Brooks, C. D., Dinh, V. Q., Young-Stubbs, C. M., Shimoura, C. G. & Mathis, K. W., 13 Jun 2022, In: Frontiers in Physiology. 13, 886779.Research output: Contribution to journal › Review article › peer-review
Open Access -
Store-operated Ca2+ channel signaling: Novel mechanism for podocyte injury in kidney disease
Tao, Y., Mallet, R. T., Mathis, K. W. & Ma, R., 2022, (Accepted/In press) In: Experimental Biology and Medicine.Research output: Contribution to journal › Short survey › peer-review
1 Scopus citations