Keyphrases
17-estradiol
100%
4-hydroxynonenal (4-HNE)
16%
Amino Group
11%
Analeptic
12%
Bioprecursor Prodrug
19%
Blood-brain Barrier
11%
Brain Delivery
13%
Brain Targeting
28%
Central Nervous System
31%
Central Nervous System Agents
17%
Chemical Delivery System
23%
Estrogen
83%
Estrogen Therapy
20%
Estrone
12%
Eye Drops
20%
Glaucoma
16%
Hot Flushes
15%
Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS)
31%
Mass Spectrometry
18%
Metabolically Stable
12%
Metabolism
17%
MS-MS
13%
Neuropeptide FF
16%
Neuropeptides
11%
Neuroprotectant
18%
Neuroprotection
24%
Neuroprotective
18%
Neuroprotective Effect
25%
Neurotherapy
11%
Nitropeptide
15%
Ocular Hypertension
13%
Oxidative Stress
19%
Para-quinol
11%
Prodrug
72%
Prodrug Strategy
15%
Proteomics
17%
Pyridinium
20%
Quinol
16%
Rat Model
11%
Redox
21%
Retina
31%
Retina Proteomics
11%
Solid Phase
15%
Synthetic Evaluation
15%
Tandem Mass Spectrometry
22%
Therapeutic Safety
18%
Thyrotropin
63%
Tripeptide
12%
Tryptophan
12%
Visual Function
15%
Pharmacology, Toxicology and Pharmaceutical Science
1,4 Dihydropyridine
8%
2,4 Dinitrophenylhydrazine
8%
4 Hydroxynonenal
6%
Acetylcholine
5%
Alzheimer's Disease
12%
Antidepressant
11%
Antioxidant
20%
Bioavailability
6%
Biological Marker
10%
Blood-Brain Barrier
12%
Carbene
6%
Carboxamide
10%
Catechol Estrogen
7%
Central Nervous System Agent
17%
Cholinergic Receptor Stimulating Agent
14%
Diethylstilbestrol
69%
Dihydropyridine
9%
Disease
8%
Drug Delivery System
10%
Drug Development
7%
Drug Metabolism
5%
Elimination
7%
Estrogen Receptor
8%
Estrone
6%
Hot Flush
15%
Hydroxyl Radical
6%
Leporidae
9%
Lipophilicity
8%
Microdialysis
6%
Mouse Model
11%
Neuropeptide
13%
Neuropeptide FF
6%
Neuroprotection
13%
Neuroprotective Agent
19%
Nitrogen 15
5%
Pharmacokinetics
11%
Prodrug
79%
Protirelin
42%
Protirelin Derivative
32%
Protirelin Receptor
7%
Pyridinium Derivative
10%
Quinone Derivative
10%
Rat Model
7%
Receptor
14%
Side Effect
16%
Stimulant
16%
Table Salt
7%
Transgenic Mouse
6%
Tripeptide
8%
Tryptophan
13%
Chemistry
2,4-dinitrophenylhydrazine
7%
Amino Group
8%
Anabaseine
7%
Antioxidant Agent
20%
Arginine
6%
Carbonylation
6%
Carboxamide
10%
Cholinergic
6%
Collision Induced Dissociation
10%
Collisionally Activated Dissociation (CAD)
10%
Derivatization
13%
Diethylstilbestrol
29%
Dihydropyridine
11%
Dilution
6%
Electron-Capture Dissociation
10%
Electrospray Ionization
15%
Estrone
14%
Free Radical
6%
Glutamine
6%
Hydroformylation
10%
Hydroxyl Radical
6%
Leu-Pro
6%
Liquid Chromatography
10%
Liquid Chromatography Mass Spectrometry
9%
Liquid Chromatography Mass Spectrometry (LCMS)
10%
Liquid Chromatography Tandem Mass Spectrometry
11%
Mass Spectrometry
15%
Mass Spectrometry
8%
Metabolic
6%
Metabolite
12%
Molecular Model
10%
Molecular Property
6%
Neuropeptide
11%
Neuropeptide FF
11%
Neuroprotective
10%
nitration
15%
Nitro Group
7%
Oxidative Stress
21%
Peptidylglycine
6%
peroxidation
12%
Pharmacokinetics
10%
Prodrug
13%
Protirelin Derivative
12%
Pyridinium Salt
6%
Reactive Oxygen Species
6%
Rhodium
7%
Stable Isotope
6%
Tandem Mass Spectrometry
36%
Tetrahydropyridine
7%
Tryptophan
8%