Keyphrases
17-estradiol
100%
Estrogen
83%
Prodrug
72%
Thyrotropin
63%
Retina
31%
Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS)
31%
Central Nervous System
31%
Brain Targeting
28%
Neuroprotective Effect
25%
Neuroprotection
24%
Chemical Delivery System
23%
Tandem Mass Spectrometry
22%
Redox
21%
Estrogen Therapy
20%
Pyridinium
20%
Eye Drops
20%
Bioprecursor Prodrug
19%
Oxidative Stress
19%
Neuroprotectant
18%
Mass Spectrometry
18%
Therapeutic Safety
18%
Neuroprotective
18%
Metabolism
17%
Proteomics
17%
Central Nervous System Agents
17%
Neuropeptide FF
16%
Glaucoma
16%
Quinol
16%
4-hydroxynonenal (4-HNE)
16%
Prodrug Strategy
15%
Nitropeptide
15%
Synthetic Evaluation
15%
Hot Flushes
15%
Visual Function
15%
Solid Phase
15%
Brain Delivery
13%
Ocular Hypertension
13%
MS-MS
13%
Estrone
12%
Tryptophan
12%
Metabolically Stable
12%
Analeptic
12%
Tripeptide
12%
Blood-brain Barrier
11%
Amino Group
11%
Retina Proteomics
11%
Neuropeptides
11%
Neurotherapy
11%
Para-quinol
11%
Rat Model
11%
Pharmacology, Toxicology and Pharmaceutical Science
Prodrug
79%
Diethylstilbestrol
69%
Protirelin
42%
Protirelin Derivative
32%
Antioxidant
20%
Neuroprotective Agent
19%
Central Nervous System Agent
17%
Stimulant
16%
Side Effect
16%
Hot Flush
15%
Cholinergic Receptor Stimulating Agent
14%
Receptor
14%
Neuroprotection
13%
Tryptophan
13%
Neuropeptide
13%
Alzheimer's Disease
12%
Blood-Brain Barrier
12%
Antidepressant
11%
Mouse Model
11%
Pharmacokinetics
11%
Carboxamide
10%
Pyridinium Derivative
10%
Quinone Derivative
10%
Drug Delivery System
10%
Biological Marker
10%
Dihydropyridine
9%
Leporidae
9%
Disease
8%
1,4 Dihydropyridine
8%
Estrogen Receptor
8%
Tripeptide
8%
2,4 Dinitrophenylhydrazine
8%
Lipophilicity
8%
Catechol Estrogen
7%
Table Salt
7%
Drug Development
7%
Elimination
7%
Protirelin Receptor
7%
Rat Model
7%
Microdialysis
6%
Neuropeptide FF
6%
Estrone
6%
4 Hydroxynonenal
6%
Bioavailability
6%
Carbene
6%
Transgenic Mouse
6%
Hydroxyl Radical
6%
Drug Metabolism
5%
Nitrogen 15
5%
Acetylcholine
5%
Chemistry
Tandem Mass Spectrometry
36%
Diethylstilbestrol
29%
Oxidative Stress
21%
Antioxidant Agent
20%
nitration
15%
Electrospray Ionization
15%
Mass Spectrometry
15%
Estrone
14%
Derivatization
13%
Prodrug
13%
Metabolite
12%
Protirelin Derivative
12%
peroxidation
12%
Neuropeptide FF
11%
Liquid Chromatography Tandem Mass Spectrometry
11%
Neuropeptide
11%
Dihydropyridine
11%
Collision Induced Dissociation
10%
Collisionally Activated Dissociation (CAD)
10%
Neuroprotective
10%
Carboxamide
10%
Molecular Model
10%
Electron-Capture Dissociation
10%
Liquid Chromatography Mass Spectrometry (LCMS)
10%
Liquid Chromatography
10%
Pharmacokinetics
10%
Hydroformylation
10%
Liquid Chromatography Mass Spectrometry
9%
Amino Group
8%
Tryptophan
8%
Mass Spectrometry
8%
Nitro Group
7%
Rhodium
7%
Tetrahydropyridine
7%
Anabaseine
7%
2,4-dinitrophenylhydrazine
7%
Arginine
6%
Free Radical
6%
Glutamine
6%
Stable Isotope
6%
Metabolic
6%
Reactive Oxygen Species
6%
Carbonylation
6%
Molecular Property
6%
Cholinergic
6%
Peptidylglycine
6%
Leu-Pro
6%
Hydroxyl Radical
6%
Dilution
6%
Pyridinium Salt
6%