Katalin Prokai-Tatrai

Personal profile

Area of Expertise

The research in my laboratory is focused on medicinal chemistry-based drug design and delivery into the central nervous system with translational medicine in mind. We focus on agents (neuropeptides and estrogens) that are beneficial for brain and retinal health. Our projects involve pharmacokinetics, metabolism and drug distribution studies in early-phase drug discovery, and the development of neuroactive/neuroprotective agents for the protection of the aging/diseased brain and retina.

Education/Academic qualification

BS in Chemical Engineering, University of Veszprem

MS in Chemistry, University of Veszprem

PhD in Organic Chemistry, University of Veszprem

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Projects

2 Active
4 Finished

A Novel Neuroprotective Approach for Glaucoma

Prokai-Tatrai, K. & Prokai, L.

NEI: National Eye Institute

1/08/16 → 31/07/21

Project: Research

A Novel Neuroprotective Approach for Glaucoma

Prokai-Tatrai, K.

NEI: National Eye Institute

1/08/16 → 31/07/21

Project: Research

A Novel Prodrug Approach to Deliver TRH into the Brain

Prokai-Tatrai, K.

Intramural Research(UNTHSC)

1/03/15 → 31/08/17

Project: Research

Novel Molecular Probes for Membrane Progesterone Receptors

Prokai-Tatrai, K.

NIA: National Institute on Aging

15/03/10 → 28/02/13

Project: Research

Novel Treatment of Menopausal Hot Flushes with an Estradiol Prodrug

Prokai, L. & Prokai-Tatrai, K.

University of Maryland, Baltimore

30/09/09 → 29/02/12

Project: Research

Research Output

1448 Citations
22 h-Index
61 Article
10 Review article
1 Chapter
1 Editorial

17β-estradiol delivered in eye drops: Evidence of impact on protein networks and associated biological processes in the rat retina through quantitative proteomics

Prokai, L., Zaman, K., Nguyen, V. & Prokai-Tatrai, K., Feb 2020, In : Pharmaceutics. 12, 2, 101.

Research output: Contribution to journal › Article

Open Access

1 Scopus citations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6

Vanden Eynde, J. J., Mangoni, A. A., Rautio, J., Leprince, J., Azuma, Y. T., García-Sosa, A. T., Hulme, C., Jampilek, J., Karaman, R., Li, W., Gomes, P. A. C., Hadjipavlou-Litina, D., Capasso, R., Geronikaki, A., Cerchia, L., Sabatier, J. M., Ragno, R., Tuccinardi, T., Trabocchi, A., Winum, J. Y. & 22 others, Luque, F. J., Prokai-Tatrai, K., Spetea, M., Gütschow, M., Kosalec, I., Guillou, C., Vasconcelos, M. H., Kokotos, G., Rastelli, G., De Sousa, M. E., Manera, C., Gemma, S., Mangani, S., Siciliano, C., Galdiero, S., Liu, H., Scott, P. J. H., De Los Ríos, C., Agrofoglio, L. A., Collina, S., Guedes, R. C. & Muñoz-Torrero, D., 2020, In : Molecules. 25, 1, 119.

Research output: Contribution to journal › Review article

Open Access