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Personal profile

Area of Expertise

The research in my laboratory is focused on medicinal chemistry-based drug design and delivery into the central nervous system with translational medicine in mind. We focus on agents (neuropeptides and estrogens) that are beneficial for brain and retinal health. Our projects involve pharmacokinetics, metabolism and drug distribution studies in early-phase drug discovery, and the development of neuroactive/neuroprotective agents for the protection of the aging/diseased brain and retina.

Education/Academic qualification

PhD in Organic Chemistry, University of Veszprem

MS in Chemistry, University of Veszprem

BS in Chemical Engineering, University of Veszprem

Fingerprint Dive into the research topics where Katalin Prokai-Tatrai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Prodrugs Medicine & Life Sciences
Thyrotropin-Releasing Hormone Medicine & Life Sciences
Brain Medicine & Life Sciences
Estrogens Medicine & Life Sciences
Mass spectrometry Chemical Compounds
Estradiol Medicine & Life Sciences
Peptides Medicine & Life Sciences
Hydroquinones Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2021

Research Output 1986 2019

  • 1323 Citations
  • 20 h-Index
  • 58 Article
  • 9 Review article
  • 1 Chapter
  • 1 Editorial

Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach

Prokai-Tatrai, K., De La Cruz, D. L., Nguyen, V., Ross, B. P., Toth, I. & Prokai, L., Jul 2019, In : Pharmaceutics. 11, 7, 349.

Research output: Contribution to journalArticle

Open Access
Thyrotropin-Releasing Hormone
Prodrugs
prolyl oligopeptidase
Brain
Peptides

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5

Mangoni, A. A., Eynde, J. J. V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M. E., Gomes, P. A. C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J. M., Luque, F. J., Rautio, J., Karaman, R., Vasconcelos, M. H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., Gütschow, M. & 6 others, Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L. A., Ragno, R. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 13, 2415.

Research output: Contribution to journalReview article

Open Access
Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 others, Gütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 1, p. 1-12 12 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations
Prodrugs
Estradiol
Brain
Estrogens
Neurology
5 Citations (Scopus)

An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease

Tschiffely, A. E., Schuh, R. A., Prokai-Tatrai, K., Ottinger, M. A. & Prokai, L., 1 Feb 2018, In : Hormones and Behavior. 98, p. 16-21 6 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Estrogens
Brain
Estradiol
Amyloid beta-Protein Precursor