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Personal profile

Area of Expertise

The research in my laboratory is focused on medicinal chemistry-based drug design and delivery into the central nervous system with translational medicine in mind. We focus on agents (neuropeptides and estrogens) that are beneficial for brain and retinal health. Our projects involve pharmacokinetics, metabolism and drug distribution studies in early-phase drug discovery, and the development of neuroactive/neuroprotective agents for the protection of the aging/diseased brain and retina.

Education/Academic qualification

PhD in Organic Chemistry, University of Veszprem

MS in Chemistry, University of Veszprem

BS in Chemical Engineering, University of Veszprem

Fingerprint Dive into the research topics where Katalin Prokai-Tatrai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Prodrugs Medicine & Life Sciences
Thyrotropin-Releasing Hormone Medicine & Life Sciences
Estrogens Medicine & Life Sciences
Brain Medicine & Life Sciences
Mass spectrometry Chemical Compounds
Estradiol Medicine & Life Sciences
Peptides Medicine & Life Sciences
Hydroquinones Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2009 2021

Research Output 1986 2019

  • 1314 Citations
  • 20 h-Index
  • 57 Article
  • 8 Review article
  • 1 Chapter
  • 1 Editorial

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 othersGütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. p. 1-12 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations

10β,17α-Dihydroxyestra-1,4-dien-3-one: A Bioprecursor Prodrug Preferentially Producing 17α-Estradiol in the Brain for Targeted Neurotherapy

Prokai-Tatrai, K., Nguyen, V. & Prokai, L., 21 Nov 2018, In : ACS Chemical Neuroscience. 9, 11, p. 2528-2533 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Prodrugs
Estradiol
Brain
Estrogens
Neurology
2 Citations (Scopus)

An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease

Tschiffely, A. E., Schuh, R. A., Prokai-Tatrai, K., Ottinger, M. A. & Prokai, L., 1 Feb 2018, In : Hormones and Behavior. 98, p. 16-21 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Alzheimer Disease
Estrogens
Brain
Estradiol
Amyloid beta-Protein Precursor

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-3

Mangoni, A. A., Tuccinardi, T., Collina, S., Vanden Eynde, J. J., Mu oz-Torrero, D., Karaman, R., Siciliano, C., Emília de Sousa, M., Prokai-Tatrai, K., Rautio, J., Guillou, C., G tschow, M., Galdiero, S., Liu, H., Agrofoglio, L. A., Sabatier, J. M., Hulme, C., Kokotos, G., You, Q. & Gomes, P. A. C., 1 Jan 2018, In : Molecules. 23, 7, 1596.

Research output: Contribution to journalReview articleResearchpeer-review

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations
1 Citation (Scopus)

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes–2

Muñoz-Torrero, D., Mangoni, A. A., Liu, H., Hulme, C., Rautio, J., Karaman, R., De Sousa, M. E., Prokai-Tatrai, K., Sabatier, J. M., Siciliano, C., Luque, F. J., Kokotos, G., Ragno, R., Collina, S., Guillou, C., Tschow, M. G. & Agrofoglio, L. A., 1 Jan 2018, In : Molecules. 23, 1, 65.

Research output: Contribution to journalReview articleResearchpeer-review

Pharmaceutical Preparations
Pharmaceutical Chemistry
Drug Discovery