Projects per year
Personal profile
Area of Expertise
The research in my laboratory is focused on medicinal chemistry-based drug design and delivery into the central nervous system with translational medicine in mind. We focus on agents (neuropeptides and estrogens) that are beneficial for brain and retinal health. Our projects involve pharmacokinetics, metabolism and drug distribution studies in early-phase drug discovery, and the development of neuroactive/neuroprotective agents for the protection of the aging/diseased brain and retina.
Education/Academic qualification
BS in Chemical Engineering, University of Veszprem
MS in Chemistry, University of Veszprem
PhD in Organic Chemistry, University of Veszprem
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Novel Neuroprotective Approach for Glaucoma
Prokai-Tatrai, K. (PI), Sumien, N. (CoI) & Prokai, L. (CoI)
1/02/23 → 31/01/28
Project: Research
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Retina-Targeted Estrogen Prodrug: A New Concept for Retinal Protection
Wu, H. (PI) & Prokai-Tatrai, K. (CoI)
30/09/20 → 29/09/23
Project: Research
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A Novel Neuroprotective Approach for Glaucoma
Prokai-Tatrai, K. (PI)
1/08/16 → 31/07/21
Project: Research
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A Novel Neuroprotective Approach for Glaucoma
Prokai-Tatrai, K. (PI) & Prokai, L. (CoI)
1/08/16 → 31/07/21
Project: Research
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A Novel Prodrug Approach to Deliver TRH into the Brain
Prokai-Tatrai, K. (PI)
1/03/15 → 31/08/17
Project: Research
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Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-3
Mangoni, A. A., Tuccinardi, T., Collina, S., Vanden Eynde, J. J., Mu oz-Torrero, D., Karaman, R., Siciliano, C., Emília de Sousa, M., Prokai-Tatrai, K., Rautio, J., Guillou, C., G tschow, M., Galdiero, S., Liu, H., Agrofoglio, L. A., Sabatier, J. M., Hulme, C., Kokotos, G., You, Q. & Gomes, P. A. C., 2018, In: Molecules. 23, 7, 1596.Research output: Contribution to journal › Review article › peer-review
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Antihypertensive Activity of Redox Derivatives of Tryptophan
Pop, E., Anderson, W., Prokai-Tatrai, K., Brewster, M. E., Bodor, N. & Fregly, M., 1990, In: Journal of Medicinal Chemistry. 33, 8, p. 2216-2221 6 p.Research output: Contribution to journal › Article › peer-review
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Synthesis and conformational analysis of a bridged anabasine and related compounds. A nuclear magnetic resonance spectroscopy and molecular modeling study.
Prokai-Tatrai, K., Zoltewicz, J. A. & Kem, W. R., 1994, In: Tetrahedron. 50, 33, p. 9909-9918 10 p.Research output: Contribution to journal › Article › peer-review
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Preparation of redox derivatives of 3α-hydroxy-5α-pregnane-11, 20-dione
Pop, E., Brewster, M. E., Prókai-Tátrai, K. & Bodor, N., Jun 1994, In: Organic Preparations and Procedures International. 26, 3, p. 379-382 4 p.Research output: Contribution to journal › Article › peer-review
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Hydroformylation of methyl methacrylate via "in-situ" phosphinerhodium catalysis
Prókai-Tátrai, K., Torös, S. & Heil, B., 6 Oct 1987, In: Journal of Organometallic Chemistry. 332, 3, p. 331-335 5 p.Research output: Contribution to journal › Article › peer-review