Projects per year
Personal profile
Area of Expertise
Dr. Joseph Malaer’s research interest is in cancer immunology, focusing on enhancing natural killer (NK) cell targeting of cancer stem cells. NK cells are a subset of lymphocytes that play an important role against cancerous cells, viruses, and bacteria. Cancer stem cells are thought to be a small population of cancer cells that have the ability to migrate, proliferate, and differentiate, and are responsible for metastasis and relapse. Dr. Malaer is interested in expanding his research to include cancer health disparities and host-pathogen interactions. In addition to research and graduate education, Dr. Malaer is heavily involved in teaching for the new undergraduate Biomedical Sciences program at UNTHSC and serves as course director for the undergraduate Immunology, Applied Molecular and Cellular Biology, and Human Physiology courses.
Education/Academic qualification
BS in Biology, St. Edward's University
MS in Medical Sciences , University of North Texas Health Science Center
PhD in Cell Biology, Immunology, & Microbiology, University of North Texas Health Science Center
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Projects
- 1 Finished
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Fostering Student Self-Directe
Malaer, J. (PI), Heck, A. (CoI) & Zascavage, R. (CoI)
International Assoc of Med Sci Educators
21/08/23 → 20/02/25
Project: Research
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2B4 (CD244, SLAMF4) and CS1 (CD319, SLAMF7) in systemic lupus erythematosus and cancer
Malaer, J. D., Marrufo, A. M. & Mathew, P. A., Jul 2019, In: Clinical Immunology. 204, p. 50-56 7 p.Research output: Contribution to journal › Review article › peer-review
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Blocking LLT1 (CLEC2D, OCIL)-NKRP1A (CD161) interaction enhances natural killer cell mediated lysis of triple-negative breast cancer cells
Marrufo, A. M., Mathew, S., Chaudhary, P., Malaer, J., Vishwanatha, J. & Mathew, P., 2018, In: American Journal of Cancer Research. 8, 6, p. 1050-1063 14 p.Research output: Contribution to journal › Article › peer-review
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Blocking PCNA interaction with NKp44 enhances primary natural killer cell-mediated lysis of triple-negative breast cancer cells
Marrufo, A. M., Mathew, S., Chaudhary, P., Malaer, J., Ahmed, N. G., Vishwanatha, J. & Mathew, P., 2023, In: American Journal of Cancer Research. 14, 3, p. 1082-1090 9 p.Research output: Contribution to journal › Article › peer-review
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Symbiosis among Lixus scrobicollis (Coleoptera: Curculionidae), Ambrosia trifida, and Bacillus endophyticus
Gans, M. J., Malaer, J. D. & Padilla, Y., 1 Sep 2014, In: Southwestern Entomologist. 39, 3, p. 469-476 8 p.Research output: Contribution to journal › Article › peer-review
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Role of LLT1 and PCNA as Natural Killer Cell Immune Evasion Strategies of HCT 116 Cells
Malaer, J. D. & Mathew, P. A., Dec 2020, In: Anticancer Research. 40, 12, p. 6613-6621 9 p.Research output: Contribution to journal › Article › peer-review