Projects per year
Personal profile
Area of Expertise
My research interests are in the areas of molecular evolutionary genetics and population genetics, and their applications for studying species and community diversity. We have worked on a broad variety of topics from wildlife conservation genetics to human population diversity and microbiomes. Previous students have focused on Alzheimer’s disease and aging, exploring both genetic/energetics coordination and messaging through microRNA signaling and epigenetic controls.
Recently we have been using new nanopore sequencing technologies to inexpensively query DNA sequences in ways that conventional approaches cannot attempt, such as full gene haplotyping and directly assaying epigenetic modifications. I am currently evaluating the evolutionary processes underlying microsatellite diversity and beginning to look into the evaluation of microbiome community structure in permaculture settings.
Recently we have been using new nanopore sequencing technologies to inexpensively query DNA sequences in ways that conventional approaches cannot attempt, such as full gene haplotyping and directly assaying epigenetic modifications. I am currently evaluating the evolutionary processes underlying microsatellite diversity and beginning to look into the evaluation of microbiome community structure in permaculture settings.
Education/Academic qualification
MS in Biology, Shippensburg University
BS in Biology and Zoology, Suny Oswego
PhD in Biology, University of North Texas
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Projects
DNA Typing Strategies via Real-Time Nanopore Sequencing for Forensic Analyses
NIJ: National Institute of Justice
1/01/19 → 31/12/20
Project: Research
Nanosensing of Oxidized Cell-free mtDNA: Biomarkers of Inflammation and Mitochondrial Dysfunction
Phillips, N., Planz, J. & Goulopoulou, S.
1/06/17 → 31/05/18
Project: Research
Application for Funding to Support the National Missing and Unidentified Persons System (NamUs)
NIJ: National Institute of Justice
1/10/16 → 30/09/18
Project: Research
NIJ FY15 DNA Capacity Enhancement and Backlog Reduction Program
NIJ: National Institute of Justice
1/01/16 → 31/12/17
Project: Research
NIJ FY15 Using DNA Technology to Identify the Missing
NIJ: National Institute of Justice
1/01/16 → 31/12/17
Project: Research
Research Output
Potential applications of nanopore sequencing for forensic analysis
Hall, C. L., Zascavage, R. R., Sedlazeck, F. J. & Planz, J. V., 1 Jan 2020, In : Forensic science review. 32, 1, p. 23-54 32 p.Research output: Contribution to journal › Review article
Approaches to Whole Mitochondrial Genome Sequencing on the Oxford Nanopore MinION
Zascavage, R. R., Hall, C. L., Thorson, K., Mahmoud, M., Sedlazeck, F. J. & Planz, J. V., 1 Dec 2019, In : Current Protocols in Human Genetics. 104, 1, e94.Research output: Contribution to journal › Article
Nanopore sequencing: An enrichment-free alternative to mitochondrial DNA sequencing
Zascavage, R. R., Thorson, K. & Planz, J. V., Jan 2019, In : Electrophoresis. 40, 2, p. 272-280 9 p.Research output: Contribution to journal › Article
2
Scopus
citations
Deep-sequencing technologies and potential applications in forensic DNA testing
Zascavage, R. R., Shewale, S. J. & Planz, J. V., 19 Aug 2013, Forensic DNA Analysis: Current Practices and Emerging Technologies. Taylor and Francis, p. 311-348 38 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1
Scopus
citations
Hidden variation in microsatellite loci: Utility and implications for forensic DNA
Planz, J. V. & Hall, T. A., 19 Aug 2013, Forensic DNA Analysis: Current Practices and Emerging Technologies. Taylor and Francis, p. 199-220 22 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter