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Jerry Simecka, PhD

  • 2629 Citations
  • 29 h-Index
1984 …2022

Research output per year

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Personal profile

Area of Expertise

Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.

Education/Academic qualification

PhD in Microbiology, University of Alabama

Award Date: 1 Jan 2001

BS in Biology, University of California at Irvine

Award Date: 1 Jan 2000

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Projects

FCCDC 2019-02: Model Development and Test Article Efficacy in a Disseminated Aspergillus and Cutaneous Fungal Infection (Aspergillus & Fusarium) Models

Simecka, J. & Weiss, W.

Fox Chase Chemical Diversity Center, Inc

22/10/19 → 21/10/20

Project: Research

Development and Validation of a Chronic Murine Lung Infection Model with S. Aureus

Simecka, J. & Weiss, W.

Janssen Pharmaceuticals

17/10/19 → 16/10/20

Project: Research

Pre-Clinical Services Agreements

Simecka, J. & Weiss, W.

Pre-Clinical Services Funding Pool

1/09/19 → 31/08/20

Project: Research

Development and Validation of a Chronic Murine Lung Infection Model with P. aeruginosa

Simecka, J. & Weiss, W.

Janssen Pharmaceuticals

18/04/19 → 17/04/20

Project: Research

Texas Center of Minority Health, Education, Research and Outreach - Admin/Development Core

Vishwanatha, J., Jones, H., He, J., Basha, R., Nandy, K., Mallet, R., Krishnamoorthy, R. & Simecka, J.

NIMHD: Natl Institute on Minority Health

23/09/17 → 31/05/22

Project: Research

Research Output

  • 2629 Citations
  • 29 h-Index
  • 77 Article
  • 4 Review article
  • 1 Comment/debate

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, W. P., Simecka, J. W., Raut, S., Ray, A. & Basha, R., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journal › Article

    • 1 Scopus citations

    Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

    Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Primary care clinics can be a source of exposure to virulent Clostridium (now Clostridioides) difficile: An environmental screening study of hospitals and clinics in Dallas-Fort Worth region

    Simecka, J. W., Fulda, K. G., Pulse, M., Lee, J. H., Vitucci, J., Nguyen, P., Taylor, P., Filipetto, F., Espinoza, A. M. & Sharma, S., 1 Jan 2019, In : PLoS ONE. 14, 8, e0220646.

    Research output: Contribution to journal › Article

    Open Access

    • Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis

    Weiss, W. J., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J. W., Valtierra, D., Sabet, M. & Griffith, D. C., Jan 2018, In : Antimicrobial agents and chemotherapy. 62, 1, e01439.

    Research output: Contribution to journal › Article

    • 7 Scopus citations

    Interleukin-17A exacerbates disease severity in BALB/c mice susceptible to lung infection with Mycoplasma pulmonis

    Mize, M. T., Sun, X. L. & Simecka, J. W., 1 Sep 2018, In : Infection and Immunity. 86, 9, e00292-18.

    Research output: Contribution to journal › Article

    • 4 Scopus citations