• 2545 Citations
  • 28 h-Index
1984 …2022
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Personal profile

Area of Expertise

Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.

Education/Academic qualification

PhD in Microbiology, University of Alabama

BS in Biology, University of California at Irvine

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2022

Research Output 1984 2019

  • 2545 Citations
  • 28 h-Index
  • 76 Article
  • 4 Review article
  • 1 Comment/debate

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival
1 Citation (Scopus)

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R. M., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Copper
Neoplasms
Powders
tolfenamic acid
Cell Line
6 Citations (Scopus)

Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis

Weiss, W., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J., Valtierra, D., Sabet, M. & Griffith, D. C., 1 Jan 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01439.

Research output: Contribution to journalArticleResearchpeer-review

meropenem
Carbapenems
Pyelonephritis
Enterobacteriaceae
Klebsiella pneumoniae

Interleukin-17A exacerbates disease severity in BALB/c mice susceptible to lung infection with Mycoplasma pulmonis

Mize, M. T., Sun, X. L. & Simecka, J., 1 Sep 2018, In : Infection and Immunity. 86, 9, e00292-18.

Research output: Contribution to journalArticleResearchpeer-review

Mycoplasma pulmonis
Interleukin-17
Lung
Mycoplasma Infections
Infection
10 Citations (Scopus)

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation

Sankpal, U. T., Ingersoll, S. B., Ahmad, S., Holloway, R. W., Bhat, V. B., Simecka, J., Daniel, L., Kariali, E., Vishwanatha, J. K. & Basha, R. M., 1 Oct 2016, In : Tumor Biology. 37, 10, p. 14259-14269 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cisplatin
Cell Proliferation
Proteins
Proteomics
Reactive Oxygen Species