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20132022

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Personal profile

Area of Expertise

Dr. Kim’s research focuses on achieving precision and personalization in gene therapy through innovative and rational optimization of nucleic acid delivery vectors. Accurate and precise delivery of nucleic acids remains a significant challenge to the clinical translation of genetic medicine for inaccessible organs.To overcome this hurdle, we are interested in coupling material science, modular engineering, high-throughput screening, machine learning, and clinical pathology to address disease-specific delivery barriers, such as ocular or neurological complications, as well as patient-specific delivery barriers, such as tumor’s genetic variability. Specifically, we will develop tissue-specific, localized gene therapy system based on nanoparticles that protect and allow transfection of nucleic acids, by facilitating the delivery across tissue-specific barrier, such as internal limiting membrane, cornea, sclera (ocular), blood brain barrier (brain), and mucosa (lungs). Also, we aim to develop and validate a novel personalized, machine learning-based optimization method for gene delivery nanoparticles based on data generated through material characterization, high-throughput transfection screening, and next generation sequencing of individual diseased tissue samples.

Education/Academic qualification

Certificate in Data Science , Harvard Extension School

Postdoctoral Fellow, Harvard University

PhD Biomedical Engineering, Johns Hopkins University

MSE Biomedical Engineering, Johns Hopkins University

BS Bioengineering, University of California at Berkeley

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