Projects per year
Personal profile
Area of Expertise
The focus of my research over the past few years has been on Alzheimer’s disease and the identification of blood-based biomarkers that can be used in the early diagnosis of the disease. I have focused on investigating risk factors for cognitive decline and dementia in the Mexican-American elderly. I have also investigated the occurrence and identification of factors leading to neuropsychiatric symptoms of Alzheimer’s such as depression, anxiety, and inappropriate behavior. Alzheimer’s is a major public health concern, and developing accessible means to predict the disease and potentially allow for intervention to prevent or slow the disease is of upmost importance. Additionally, being able to identify those with the disease who are most likely to develop neuropsychiatric symptoms (the primary cause of caregiver stress and nursing home placement) can lead to early intervention and provide the groundwork for understanding the pathophysiology of neuropsychiatric symptoms of dementia. Developing treatment approaches for the pre-clinical stage of Alzheimer’s disease to reduce the risk of developing neurodegenerative diseases is crucial to our aging population.
Education/Academic qualification
BA in History, University of Iowa
PhD in Clinical Psychology, University of Nevada, Reno
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Multi-omic Investigation of Exercise Effects in Mild Cognitive Impairment
University of California - Irvine
1/07/18 → 28/02/22
Project: Research
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A Blood Test for Screening into Alzheimer's Prevention Trials
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
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A Blood Test for Screening into Alzheimer's Prevention Trials
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
15/09/17 → 30/06/22
Project: Research
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Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican Americans
O'Bryant, S., Hall, J. & Johnson, L.
NIA: National Institute on Aging
1/09/17 → 31/05/22
Project: Research
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Analysis of a precision medicine approach to treating Parkinson's disease: Analysis of the DATATOP study
O'Bryant, S. E., Petersen, M., Zhang, F., Johnson, L., Mason, D. & Hall, J., Jan 2022, In: Parkinsonism and Related Disorders. 94, p. 15-21 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, 2021, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
Accelerating Hyperparameter Tuning in Machine Learning for Alzheimer’s Disease With High Performance Computing
Zhang, F., Petersen, M., Johnson, L., Hall, J. & O’Bryant, S. E., 8 Dec 2021, In: Frontiers in Artificial Intelligence. 4, 798962.Research output: Contribution to journal › Article › peer-review
Open Access -
A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
O'Bryant, S. E., Zhang, F., Petersen, M., Johnson, L., Hall, J. & Rissman, R. A., 2021, In: Journal of Alzheimer's Disease. 81, 2, p. 557-568 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study
for the HABLE Study Team, 2021, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access