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Personal profile

Area of Expertise

The focus of my research over the past few years has been on Alzheimer’s disease and the identification of blood-based biomarkers that can be used in the early diagnosis of the disease. I have focused on investigating risk factors for cognitive decline and dementia in the Mexican-American elderly. I have also investigated the occurrence and identification of factors leading to neuropsychiatric symptoms of Alzheimer’s such as depression, anxiety, and inappropriate behavior. Alzheimer’s is a major public health concern, and developing accessible means to predict the disease and potentially allow for intervention to prevent or slow the disease is of upmost importance. Additionally, being able to identify those with the disease who are most likely to develop neuropsychiatric symptoms (the primary cause of caregiver stress and nursing home placement) can lead to early intervention and provide the groundwork for understanding the pathophysiology of neuropsychiatric symptoms of dementia. Developing treatment approaches for the pre-clinical stage of Alzheimer’s disease to reduce the risk of developing neurodegenerative diseases is crucial to our aging population.

Education/Academic qualification

PhD in Clinical Psychology, University of Nevada, Reno

BA in History, University of Iowa

Fingerprint Dive into the research topics where James Hall is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 20 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Dementia Medicine & Life Sciences
Depression Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Cognition Medicine & Life Sciences
Hispanic Americans Medicine & Life Sciences
Endophenotypes Medicine & Life Sciences
Neuropsychological Tests Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2024

Research Output 2006 2020

  • 1482 Citations
  • 19 h-Index
  • 73 Article
  • 2 Review article
  • 1 Short survey

Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly

Liu, X., Chen, X., Kline, G., Ross, S. E., Hall, J. R., Ding, Y., Mallet, R. T. & Shi, X., Jan 2020, In : Respiratory Physiology and Neurobiology. 271, 103306.

Research output: Contribution to journalArticle

Blood Vessels
Hypoxia
Heart Rate
Ventilation
Young Adult
1 Citation (Scopus)

A proteomic signature for dementia with Lewy bodies

O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journalArticle

Open Access
Lewy Body Disease
Proteomics
Parkinson Disease
Dementia
Sensitivity and Specificity

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

Winston, C. N., Romero, H. K., Ellisman, M., Nauss, S., Julovich, D. A., Conger, T., Hall, J. R., Campana, W., O’Bryant, S. E., Nievergelt, C. M., Baker, D. G., Risbrough, V. B. & Rissman, R. A., 2 Oct 2019, In : Frontiers in Neuroscience. 13, 1005.

Research output: Contribution to journalArticle

Open Access
Brain Concussion
Exosomes
Astrocytes
Proteins
Neurogranin

Potential two-step proteomic signature for Parkinson's disease: Pilot analysis in the Harvard Biomarkers Study

O'Bryant, S., Edwards, M., Zhang, F., Johnson, L. A., Hall, J., Kuras, Y. & Scherzer, C. R., 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 374-382 9 p.

Research output: Contribution to journalArticle

Open Access
Neurodegenerative Diseases
Proteomics
Parkinson Disease
Biomarkers
Alzheimer Disease
Open Access
Hispanic Americans
C-Reactive Protein
Cognition
Cross-Sectional Studies
Health