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James Hall, PhD

  • 1686 Citations
  • 20 h-Index
20062024

Research output per year

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Personal profile

Area of Expertise

The focus of my research over the past few years has been on Alzheimer’s disease and the identification of blood-based biomarkers that can be used in the early diagnosis of the disease. I have focused on investigating risk factors for cognitive decline and dementia in the Mexican-American elderly. I have also investigated the occurrence and identification of factors leading to neuropsychiatric symptoms of Alzheimer’s such as depression, anxiety, and inappropriate behavior. Alzheimer’s is a major public health concern, and developing accessible means to predict the disease and potentially allow for intervention to prevent or slow the disease is of upmost importance. Additionally, being able to identify those with the disease who are most likely to develop neuropsychiatric symptoms (the primary cause of caregiver stress and nursing home placement) can lead to early intervention and provide the groundwork for understanding the pathophysiology of neuropsychiatric symptoms of dementia. Developing treatment approaches for the pre-clinical stage of Alzheimer’s disease to reduce the risk of developing neurodegenerative diseases is crucial to our aging population.

Education/Academic qualification

PhD in Clinical Psychology, University of Nevada, Reno

Award Date: 1 Jan 2001

BA in History, University of Iowa

Award Date: 1 Jan 2000

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Projects

Blood-Based Biomarker Profiles for a Precision Medicine Approach to Parkinsons Disease

O'Bryant, S., Hall, J. & Nandy, R.

Michael J. Fox Fnd for Parkinson's Res

15/10/19 → 14/10/20

Project: Research

Blood Biomarkers for Discriminating Amongst Neurodegenerative Diseases

O'Bryant, S., Hall, J. & Nandy, R.

Michael J. Fox Fnd for Parkinson's Res

1/06/19 → 31/05/20

Project: Research

Blood-Brain Barrier Disruption as a Biomarker for Peroperative Neurocognitive Disorders: Cognitive Recovery after Elective Surgery (CREATES) Study

O'Bryant, S. & Hall, J.

Rhode Island Hospital

1/05/19 → 29/02/24

Project: Research

Multi-omic Investigation of Exercise Effects in Mild Cognitive Impairment

O'Bryant, S. & Hall, J.

University of California - Irvine

1/07/18 → 28/02/22

Project: Research

Neurodegeneration in Aging Down Syndrome (NiAD): A Longitudinal Study of Cognition and Biomarkers of Alzheimer's Disease

O'Bryant, S. & Hall, J.

University of Pittsburgh

1/07/18 → 30/04/20

Project: Research

Research Output

  • 1686 Citations
  • 20 h-Index
  • 75 Article
  • 2 Review article
  • 1 Short survey

Intermittent Hypoxia Training for Treating Mild Cognitive Impairment: A Pilot Study

Wang, H., Shi, X., Schenck, H., Hall, J. R., Ross, S. E., Kline, G. P., Chen, S., Mallet, R. T. & Chen, P., 1 Jan 2020, In : American journal of Alzheimer's disease and other dementias. 35, p. 1533317519896725

Research output: Contribution to journal › Article

Open Access

    • Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly

    Liu, X., Chen, X., Kline, G., Ross, S. E., Hall, J. R., Ding, Y., Mallet, R. T. & Shi, X., Jan 2020, In : Respiratory Physiology and Neurobiology. 271, 103306.

    Research output: Contribution to journal › Article

    • The impact of comorbid depression-diabetes on proteomic outcomes among community-dwelling Mexican Americans with mild cognitive impairment

    Johnson, L. A., Zhang, F., Large, S., Hall, J. & O'bryant, S. E., 1 Jan 2020, In : International Psychogeriatrics. 32, 1, p. 17-23 7 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    A proteomic signature for dementia with Lewy bodies

    O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

    Winston, C. N., Romero, H. K., Ellisman, M., Nauss, S., Julovich, D. A., Conger, T., Hall, J. R., Campana, W., O’Bryant, S. E., Nievergelt, C. M., Baker, D. G., Risbrough, V. B. & Rissman, R. A., 2 Oct 2019, In : Frontiers in Neuroscience. 13, 1005.

    Research output: Contribution to journal › Article

    Open Access