Projects per year
Personal profile
Area of Expertise
My laboratory research focuses on two intersecting areas:
1) Molecular progression of breast and prostate cancers to aggressive phenotype,
2) Nanotechnology approaches for targeted therapeutics. In one of our studies, we are determining the role of exosomal annexin A2 in metastatic progression of breast and prostate cancers. In another project, we are studying how MIEN1 (a protein that was discovered in our lab) promotes migration and invasion of cancer cells leading to metastatic progression. We are also utilizing novel targeted nanodevices for treatment of bone metastatic prostate cancer and for metastatic triple negative breast cancer.
1) Molecular progression of breast and prostate cancers to aggressive phenotype,
2) Nanotechnology approaches for targeted therapeutics. In one of our studies, we are determining the role of exosomal annexin A2 in metastatic progression of breast and prostate cancers. In another project, we are studying how MIEN1 (a protein that was discovered in our lab) promotes migration and invasion of cancer cells leading to metastatic progression. We are also utilizing novel targeted nanodevices for treatment of bone metastatic prostate cancer and for metastatic triple negative breast cancer.
Education/Academic qualification
BS in Genetics, University of Agricultural Sciences, Bangalore
MS in Genetics, University of Agricultural Sciences, Bangalore
PhD in Biology, University of South Carolina
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Projects
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NRMNet: A national resource for mentorship and networking to enhance diversity
NIGMS: General Medical Sciences
1/07/19 → 30/06/24
Project: Research
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NRMNet: A national resource for mentorship and networking to enhance diversity
1/07/19 → 30/06/21
Project: Research
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NRMNet: A national resource for mentorship and networking to enhance diversity
NIMHD: Natl Institute on Minority Health
1/07/19 → 30/06/24
Project: Research
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2/2 Langston University-UNTHSC Partnership for Cancer Research and Education Core
NCI: National Cancer Institute
20/09/18 → 31/08/22
Project: Research
Research Output
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Comparative analysis of racial differences in breast tumor microbiome
Thyagarajan, S., Zhang, Y., Thapa, S., Allen, M. S., Phillips, N., Chaudhary, P., Kashyap, M. V. & Vishwanatha, J. K., 1 Dec 2020, In: Scientific Reports. 10, 1, 14116.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Comparative expression analysis of phospholipid binding protein annexina1 in nephrogenesis and kidney cancer
Sadashiv, R., Bannur, B. M., Shetty, P., Dinesh, U. S., K.vishwanatha, J., Deshpande, S. K., Bargale, A., Sarathkumar, E. & Ruikar, K., 1 Jul 2020, In: Journal of Basic and Clinical Physiology and Pharmacology. 31, 4, 20190179.Research output: Contribution to journal › Article › peer-review
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Erratum: Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis (Breast Cancer Research (2020) 22 (11) DOI: 10.1186/s13058-020-1251-8)
Chaudhary, P., Gibbs, L. D., Maji, S., Lewis, C. M., Suzuki, S. & Vishwanatha, J. K., 23 Mar 2020, In: Breast Cancer Research. 22, 1, 31.Research output: Contribution to journal › Comment/debate
Open Access2 Scopus citations -
Grant application outcomes for biomedical researchers who participated in the National Research Mentoring Network's Grant Writing Coaching Programs
Weber-Main, A. M., McGee, R., Boman, K. E., Hemming, J., Hall, M., Unold, T., Harwood, E. M., Risner, L. E., Smith, A., Lawson, K., Engler, J., Steer, C. J., Buchwald, D., Jones, H. P., Manson, S. M., Ofili, E., Schwartz, N. B., Vishwanatha, J. K. & Okuyemi, K. S., Nov 2020, In: PLoS ONE. 15, 11 November, e0241851.Research output: Contribution to journal › Article › peer-review
Open Access -
Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells
Hurtado, M., Prokai, L., Sankpal, U. T., Levesque, B., Maram, R., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K. & Basha, R., Feb 2020, In: Process Biochemistry. 89, p. 155-164 10 p.Research output: Contribution to journal › Article › peer-review