Calculated based on number of publications stored in Pure and citations from Scopus
1983 …2020

Research activity per year

Personal profile

Area of Expertise

In my laboratory research, I am working in translational research of cancer to develop multiple methods for gene and cell therapy, particularly in the use of virus-based and nanoparticle delivery vehicles. I have worked extensively with oncolytic virus vectors for many years, and my laboratory is modifying capsid proteins on virus vectors for cancer retargeting, as well as developing cancer vaccines and conditionally replicating virus vectors for cancer therapy. I have extensive experience in analysis of gene expression using quantitative RT-PCR. In support of translational cancer studies in my laboratory, I have extensive experience immortalizing cell lines from primary tumors and performing co-culture experiments. I have established small animal imaging capability, and I have worked to develop methods for non-invasive monitoring of oncolytic virus and nanoparticle biodistribution in vivo. Among the various methods I have developed are novel modifications of virus capsid proteins to allow SPECT (single photon emission computed tomography) imaging in vivo.

Education/Academic qualification

MHA, Louisiana State University

BS in Chemistry, Texas A & M University

EdD, University of Alabama

PhD Biochemistry, University of Texas Southwestern Medical Center

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