• 14404 Citations
  • 57 h-Index
1975 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Area of Expertise

My research interests cover fluorescence spectroscopy and its applications in biochemistry and biology. I am developing advanced fluorescence-based techniques for ultra-sensitive detection of analytes and biomedical agents. In particular, we have developed a FRET-based method for the selective detection of a metalloproteinase 9 enzyme (MMP-9) and micro RNAs. The enhanced detection of minute amounts of dye molecules has been achieved with a Metal Enhanced Fluorescence (MEF). Several plasmonic platforms have been developed and tested for MEF. These include silver island films, silver fractals, and silver nanowires deposited on glass/sapphire substrates. We demonstrated several hundredfold enhancements of the fluorescence signals by using our plasmonic platforms. We also applied surface plasmon coupled emission (SPCE) in fluorescence microscopy. SPCE transforms an isotropic fluorescence emission into a directional, fully polarized radiation. The SPCE radiation preserves all spectral properties of used fluorophores and offers a significant reduction of unwanted fluorescence background because of minimization of the excitation volume.

Education/Academic qualification

MS in Physics, University of Gdańsk

PhD in Physics, University of Gdańsk

Fingerprint Dive into the research topics where Ignacy Gryczynski is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.


Research Output

On the origin and correction for inner filter effects in fluorescence Part I: Primary inner filter effect-the proper approach for sample absorbance correction

Kimball, J., Chavez, J., Ceresa, L., Kitchner, E., Nurekeyev, Z., Doan, H., Szabelski, M., Borejdo, J., Gryczynski, I., Gryczynski, Z. & Gryczynski, Z., Jul 2020, In : Methods and Applications in Fluorescence. 8, 3, 033002.

Research output: Contribution to journalArticle

  • 1 Scopus citations

    On the possibility of direct triplet state excitation of indole

    Chavez, J., Ceresa, L., Kitchner, E., Kimball, J., Shtoyko, T., Fudala, R., Borejdo, J., Gryczynski, Z. & Gryczynski, I., Jul 2020, In : Journal of Photochemistry and Photobiology B: Biology. 208, 111897.

    Research output: Contribution to journalArticle

  • Probing the assembly of HDL mimetic, drug carrying nanoparticles using intrinsic fluorescences

    Raut, S., Garud, A., Nagarajan, B., Sabnis, N., Remaley, A., Fudala, R., Gryczynski, I., Gryczynski, Z., Dzyuba, S. V., Borejdo, J. & Lacko, A., 1 Apr 2020, In : Journal of Pharmacology and Experimental Therapeutics. 373, 1, p. 113-121 9 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    The luminescence of 1,8-Diazafluoren-9-One/Titanium dioxide composite thin films for optical application

    Lewkowicz, A., Bogdanowicz, R., Bojarski, P., Pierpaoli, M., Gryczyński, I., Synak, A., Mońka, M., Karczewski, J., Struck-Lewicka, W., Wawrzyniak, R. & Markuszewski, M. J., 1 Jul 2020, In : Materials. 13, 13, 3014.

    Research output: Contribution to journalArticle

    Open Access