Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
BS in Pharmacy, Xinjiang Medical University
MS in Pharmacy, Xinjiang Medical University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Racial disparities of open ang
Wu, H. (PI)
Washington University in St. Louis
30/09/23 → 30/06/28
Project: Research
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Mechanistic Insights and Therapeutic Potential of the Glutaredoxin (Grx) System in the Lens
Wu, H. (PI)
1/02/23 → 31/01/25
Project: Research
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Down-regulation of brain-pancreas relative protein in diabetic rats and by high glucose in PC12 cells: Prevention by calpain inhibitors
Tie, L., Xu, Y., Lin, Y. H., Yao, X. H., Wu, H. L., Li, Y. H., Shen, Z. F., Yu, H. M. & Li, X. J., 2008, In: Journal of Pharmacological Sciences. 106, 1, p. 28-37 10 p.Research output: Contribution to journal › Article › peer-review
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Overexpression of thioredoxin-binding protein 2increases oxidation sensitivity and apoptosis in human lens epithelialcells
Yu, Y., Xing, K., Badamas, R., Kuszynski, C. A., Wu, H. & Lou, M. F., Apr 2013, In: Free Radical Biology and Medicine. 57, p. 92-104 13 p.Research output: Contribution to journal › Article › peer-review
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N-Acetylcysteine amide (NACA) and diNACA inhibit H2O2-induced cataract formation ex vivo in pig and rat lenses
Martis, R. M., Grey, A. C., Wu, H., Wall, G. M., Donaldson, P. J. & Lim, J. C., Sep 2023, In: Experimental eye research. 234, 109610.Research output: Contribution to journal › Article › peer-review
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Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB
Wang, R., Li, Y. B., Li, Y. H., Xu, Y., Wu, H. L. & Li, X. J., 19 May 2008, In: Brain Research. 1210, p. 84-91 8 p.Research output: Contribution to journal › Article › peer-review
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A grape-supplemented diet prevented ultraviolet (UV) radiation-induced cataract by regulating Nrf2 and XIAP pathways
Liu, X., Yu, Y., Garcia, L. A., Au, M. L., Tran, M., Zhang, J., Lou, A., Liu, Y. & Wu, H., Jul 2024, In: Journal of Nutritional Biochemistry. 129, 109636.Research output: Contribution to journal › Article › peer-review