Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
BS in Pharmacy, Xinjiang Medical University
MS in Pharmacy, Xinjiang Medical University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Racial disparities of open ang
Wu, H. (PI)
Washington University in St. Louis
30/09/23 → 30/06/28
Project: Research
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Mechanistic Insights and Therapeutic Potential of the Glutaredoxin (Grx) System in the Lens
Wu, H. (PI)
1/02/23 → 31/01/25
Project: Research
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Retina-Targeted Estrogen Prodrug: A New Concept for Retinal Protection
Wu, H. (PI) & Prokai-Tatrai, K. (CoI)
30/09/20 → 29/09/23
Project: Research
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A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage
Zhang, J., Yu, Y., Mekhail, M. A., Wu, H. & Green, K. N., 28 Oct 2022, In: Frontiers in Chemistry. 10, 996604.Research output: Contribution to journal › Article › peer-review
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Salvianolic acid B (Sal B) protects retinal pigment epithelial cells from oxidative stress-induced cell death by activating glutaredoxin 1 (Grx1)
Liu, X., Xavier, C., Jann, J. & Wu, H., 3 Nov 2016, In: International journal of molecular sciences. 17, 11, 1835.Research output: Contribution to journal › Article › peer-review
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Enhancement of the Antioxidant Activity and Neurotherapeutic Features through Pyridol Addition to Tetraazamacrocyclic Molecules
Johnston, H. M., Pota, K., Barnett, M. M., Kinsinger, O., Braden, P., Schwartz, T. M., Hoffer, E., Sadagopan, N., Nguyen, N., Yu, Y., Gonzalez, P., Tircsó, G., Wu, H., Akkaraju, G., Chumley, M. J. & Green, K. N., 16 Dec 2019, In: Inorganic Chemistry. 58, 24, p. 16771-16784 14 p.Research output: Contribution to journal › Article › peer-review
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Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cells
Li, Y. B., Wang, R., Wu, H. L., Li, Y. H., Zhong, L. J., Yu, H. M. & Li, X. J., Sep 2008, In: Oncology Reports. 20, 3, p. 549-556 8 p.Research output: Contribution to journal › Article › peer-review
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Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons
Wang, R., Li, Y. H., Xu, Y., Li, Y. B., Wu, H. L., Guo, H., Zhang, J. Z., Zhang, J. J., Pan, X. Y. & Li, X. J., 20 Jan 2010, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 34, 1, p. 147-153 7 p.Research output: Contribution to journal › Article › peer-review