Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
BS in Pharmacy, Xinjiang Medical University
MS in Pharmacy, Xinjiang Medical University
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Projects
- 12 Finished
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Evaluate NACA and diNACA in Preventing Oxidative Stress-Induced Cataract Formation: Ex Vivo Study
7/10/19 → 6/10/20
Project: Research
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To evaluate the oxidative efficacy of L2 and L4 compounds in PC12 cells
22/01/19 → 21/01/20
Project: Research
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Enhancement of the Antioxidant Activity and Neurotherapeutic Features through Pyridol Addition to Tetraazamacrocyclic Molecules
Johnston, H. M., Pota, K., Barnett, M. M., Kinsinger, O., Braden, P., Schwartz, T. M., Hoffer, E., Sadagopan, N., Nguyen, N., Yu, Y., Gonzalez, P., Tircsó, G., Wu, H., Akkaraju, G., Chumley, M. J. & Green, K. N., 16 Dec 2019, In: Inorganic Chemistry. 58, 24, p. 16771-16784 14 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Cataract preventive role of isolated phytoconstituents: Findings from a decade of research
Lim, V., Schneider, E., Wu, H. & Pang, I. H., Nov 2018, In: Nutrients. 10, 11, 1580.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Involvement of Nrf2 in ocular diseases
Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I. H., 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 1703810.Research output: Contribution to journal › Review article › peer-review
29 Scopus citations -
Salvianolic acid B (Sal B) protects retinal pigment epithelial cells from oxidative stress-induced cell death by activating glutaredoxin 1 (Grx1)
Liu, X., Xavier, C., Jann, J. & Wu, H., 3 Nov 2016, In: International journal of molecular sciences. 17, 11, 1835.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A. F., Pang, I. H. & Wu, H., 1 Aug 2016, In: Redox Biology. 8, p. 98-109 12 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations