Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
MS in Pharmacy, Xinjiang Medical University
BS in Pharmacy, Xinjiang Medical University
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Glutaredoxins
Medicine & Life Sciences
Oxidative Stress
Medicine & Life Sciences
Oxidative stress
Chemical Compounds
Curcumin
Medicine & Life Sciences
Retinal Pigments
Medicine & Life Sciences
PC12 Cells
Medicine & Life Sciences
Epithelial Cells
Medicine & Life Sciences
Lenses
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2020
To evaluate the oxidative efficacy of L2 and L4 compounds in PC12 cells
22/01/19 → 21/01/20
Project: Research
Assessment the Effect of Femtosecond Laser-based Device on Biochemical Paramenters in the Lens
24/10/17 → 23/10/18
Project: Research
Shared Instrumentation Grant for the High Resolution Slit Lamp Imaging System
1/10/16 → 30/09/17
Project: Research
Research Output 2006 2018
Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research
Lim, V., Schneider, E., Wu, H. & Pang, I-H., 26 Oct 2018, In : Nutrients. 10, 11Research output: Contribution to journal › Review article › Research › peer-review
chemical constituents of plants
cataract
Cataract
Research
eye lens
8
Citations
(Scopus)
Involvement of Nrf2 in ocular diseases
Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I-H., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1703810.Research output: Contribution to journal › Review article › Research › peer-review
Eye Diseases
Antioxidants
Oxidative stress
Macular Degeneration
Diabetic Retinopathy
8
Citations
(Scopus)
Salvianolic acid B (Sal B) protects retinal pigment epithelial cells from oxidative stress-induced cell death by activating glutaredoxin 1 (Grx1)
Liu, X., Xavier, C., Jann, J. & Wu, H., 3 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 1835.Research output: Contribution to journal › Article › Research › peer-review
Glutaredoxins
Oxidative stress
Retinal Pigments
Cell death
pigments
19
Citations
(Scopus)
The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A., Pang, I-H. & Wu, H., 1 Aug 2016, In : Redox Biology. 8, p. 98-109 12 p.Research output: Contribution to journal › Article › Research › peer-review
NF-E2-Related Factor 2
Retinal Pigments
Epithelial Cells
Chemical activation
Oxidative stress
4
Citations
(Scopus)
Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues
Upadhyaya, B., Tian, X., Wu, H. & Lou, M. F., 1 Jan 2015, In : Experimental Eye Research. 130, p. 58-65 8 p.Research output: Contribution to journal › Article › Research › peer-review
Glutaredoxins
Sulfhydryl Compounds
Ciliary Body
Swine
Lenses