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Hongli (Catherine) Wu, PhD

  • 711 Citations
  • 13 h-Index
20062019

Research output per year

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Personal profile

Area of Expertise

Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.

Education/Academic qualification

PhD in Pharmacology, Peking University

BS in Pharmacy, Xinjiang Medical University

MS in Pharmacy, Xinjiang Medical University

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Projects

Evaluate NACA and diNACA in Cone Cells +/- Oxidative Stress

Wu, H. (.

Nacuity Pharmaceuticals, Inc.

7/10/19 → 6/10/20

Project: Research

Evaluate NACA and diNACA in Preventing Oxidative Stress-Induced Cataract Formation: Ex Vivo Study

Wu, H. (.

Nacuity Pharmaceuticals, Inc.

7/10/19 → 6/10/20

Project: Research

Goal: Using ATP Level as a Marker for Laser Setting Optimization

Wu, H. (.

Lensar, Inc.

1/07/19 → 30/06/20

Project: Research

Evaluation of NAC, NACA and diNACA in Cultured RPE Cells and in Cultured Corneal Endothelial Cells (CECs) +/- Oxidative Stress

Clark, A. & Wu, H. (.

Nacuity Pharmaceuticals, Inc.

18/02/19 → 4/06/20

Project: Research

To evaluate the oxidative efficacy of L2 and L4 compounds in PC12 cells

Wu, H. (.

Texas Christian University

22/01/19 → 21/01/20

Project: Research

Research Output

  • 711 Citations
  • 13 h-Index
  • 18 Article
  • 2 Review article

Enhancement of the Antioxidant Activity and Neurotherapeutic Features through Pyridol Addition to Tetraazamacrocyclic Molecules

Johnston, H. M., Pota, K., Barnett, M. M., Kinsinger, O., Braden, P., Schwartz, T. M., Hoffer, E., Sadagopan, N., Nguyen, N., Yu, Y., Gonzalez, P., Tircsó, G., Wu, H., Akkaraju, G., Chumley, M. J. & Green, K. N., 16 Dec 2019, In : Inorganic Chemistry. 58, 24, p. 16771-16784 14 p.

Research output: Contribution to journal › Article

    • 1 Scopus citations

    Cataract preventive role of isolated phytoconstituents: Findings from a decade of research

    Lim, V., Schneider, E., Wu, H. & Pang, I. H., Nov 2018, In : Nutrients. 10, 11, 1580.

    Research output: Contribution to journal › Review article

    • 3 Scopus citations

    Involvement of Nrf2 in ocular diseases

    Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I. H., 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1703810.

    Research output: Contribution to journal › Review article

    • 23 Scopus citations

    Salvianolic acid B (Sal B) protects retinal pigment epithelial cells from oxidative stress-induced cell death by activating glutaredoxin 1 (Grx1)

    Liu, X., Xavier, C., Jann, J. & Wu, H., 3 Nov 2016, In : International journal of molecular sciences. 17, 11, 1835.

    Research output: Contribution to journal › Article

    • 16 Scopus citations

    The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

    Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A. F., Pang, I. H. & Wu, H., 1 Aug 2016, In : Redox Biology. 8, p. 98-109 12 p.

    Research output: Contribution to journal › Article

    • 28 Scopus citations