Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
BS in Pharmacy, Xinjiang Medical University
MS in Pharmacy, Xinjiang Medical University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanistic Insights and Therapeutic Potential of the Glutaredoxin (Grx) System in the Lens
1/02/23 → 31/01/24
Project: Research
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Evaluate NACA and diNACA in Preventing Oxidative Stress-Induced Cataract Formation: Ex Vivo Study
7/10/19 → 6/10/20
Project: Research
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A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage
Zhang, J., Yu, Y., Mekhail, M. A., Wu, H. & Green, K. N., 28 Oct 2022, In: Frontiers in Chemistry. 10, 996604.Research output: Contribution to journal › Article › peer-review
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The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A. F., Pang, I. H. & Wu, H., 1 Aug 2016, In: Redox Biology. 8, p. 98-109 12 p.Research output: Contribution to journal › Article › peer-review
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The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors
Wang, R., Xu, Y., Wu, H. L., Li, Y. B., Li, Y. H., Guo, J. B. & Li, X. J., 6 Jan 2008, In: European Journal of Pharmacology. 578, 1, p. 43-50 8 p.Research output: Contribution to journal › Article › peer-review
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Glutaredoxin 1 (Grx1) protects human retinal pigment epithelial cells from oxidative damage by preventing AKT glutathionylation
Liu, X., Jann, J., Xavier, C. & Wu, H., 2015, In: Investigative Ophthalmology and Visual Science. 56, 5, p. 2821-2832 12 p.Research output: Contribution to journal › Article › peer-review
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Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents Aβ25-35-induced reduction in BPRP in PC12 cells
Lin, Y. H., Liu, A. H., Wu, H. L., Westenbroek, C., Song, Q. L., Yu, H. M., Ter Horst, G. J. & Li, X. J., 22 Sep 2006, In: Biochemical and Biophysical Research Communications. 348, 2, p. 593-599 7 p.Research output: Contribution to journal › Article › peer-review