Projects per year
Personal profile
Area of Expertise
Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.
Education/Academic qualification
PhD in Pharmacology, Peking University
BS in Pharmacy, Xinjiang Medical University
MS in Pharmacy, Xinjiang Medical University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Racial disparities of open angle glaucoma: A study of mitochondria and oxidative stress in human trabecular meshwork
Wu, H. (PI)
Washington University in St. Louis
30/09/23 → 30/06/28
Project: Research
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Mechanistic Insights and Therapeutic Potential of the Glutaredoxin (Grx) System in the Lens
Wu, H. (PI)
1/02/23 → 31/01/25
Project: Research
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Mechanistic Insights and Therapeutic Potential of the Glutaredoxin (Grx) System in the Lens
Wu, H. (PI)
1/02/23 → 31/01/25
Project: Research
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Retina-Targeted Estrogen Prodrug: A New Concept for Retinal Protection
Wu, H. (PI) & Prokai-Tatrai, K. (CoI)
30/09/20 → 29/09/23
Project: Research
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Serum amyloid A mediates the inhibitory effect of Ganoderma lucidum polysaccharides on tumor cell adhesion to endothelial cells
Li, Y. B., Wang, R., Wu, H. L., Li, Y. H., Zhong, L. J., Yu, H. M. & Li, X. J., Sep 2008, In: Oncology Reports. 20, 3, p. 549-556 8 p.Research output: Contribution to journal › Article › peer-review
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Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents Aβ25-35-induced reduction in BPRP in PC12 cells
Lin, Y. H., Liu, A. H., Wu, H. L., Westenbroek, C., Song, Q. L., Yu, H. M., Ter Horst, G. J. & Li, X. J., 22 Sep 2006, In: Biochemical and Biophysical Research Communications. 348, 2, p. 593-599 7 p.Research output: Contribution to journal › Article › peer-review
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Cataract preventive role of isolated phytoconstituents: Findings from a decade of research
Lim, V., Schneider, E., Wu, H. & Pang, I. H., Nov 2018, In: Nutrients. 10, 11, 1580.Research output: Contribution to journal › Review article › peer-review
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Glutaredoxin 2 prevents H2O2-induced cell apoptosis by protecting complex I activity in the mitochondria
Wu, H., Xing, K. & Lou, M. F., Oct 2010, In: Biochimica et Biophysica Acta - Bioenergetics. 1797, 10, p. 1705-1715 11 p.Research output: Contribution to journal › Article › peer-review
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Enhancement of the Antioxidant Activity and Neurotherapeutic Features through Pyridol Addition to Tetraazamacrocyclic Molecules
Johnston, H. M., Pota, K., Barnett, M. M., Kinsinger, O., Braden, P., Schwartz, T. M., Hoffer, E., Sadagopan, N., Nguyen, N., Yu, Y., Gonzalez, P., Tircsó, G., Wu, H., Akkaraju, G., Chumley, M. J. & Green, K. N., 16 Dec 2019, In: Inorganic Chemistry. 58, 24, p. 16771-16784 14 p.Research output: Contribution to journal › Article › peer-review