• 575 Citations
  • 11 h-Index
20062020
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Personal profile

Area of Expertise

Areas of research and interests include:
1) examining how retinal redox imbalance leads to age-related macular degeneration (AMD) pathogenesis;
2) characterizing glutaredoxin 2 (Grx2) knockout mice as a new animal model for AMD;
3) identifying/screening Grx2 inducers from natural products for AMD treatment.

Education/Academic qualification

PhD in Pharmacology, Peking University

MS in Pharmacy, Xinjiang Medical University

BS in Pharmacy, Xinjiang Medical University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2020

Research Output 2006 2018

  • 575 Citations
  • 11 h-Index
  • 17 Article
  • 2 Review article

Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

Lim, V., Schneider, E., Wu, H. & Pang, I-H., 26 Oct 2018, In : Nutrients. 10, 11

Research output: Contribution to journalReview articleResearchpeer-review

chemical constituents of plants
cataract
Cataract
Research
eye lens
8 Citations (Scopus)

Involvement of Nrf2 in ocular diseases

Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I-H., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1703810.

Research output: Contribution to journalReview articleResearchpeer-review

Eye Diseases
Antioxidants
Oxidative stress
Macular Degeneration
Diabetic Retinopathy
8 Citations (Scopus)

Salvianolic acid B (Sal B) protects retinal pigment epithelial cells from oxidative stress-induced cell death by activating glutaredoxin 1 (Grx1)

Liu, X., Xavier, C., Jann, J. & Wu, H., 3 Nov 2016, In : International Journal of Molecular Sciences. 17, 11, 1835.

Research output: Contribution to journalArticleResearchpeer-review

Glutaredoxins
Oxidative stress
Retinal Pigments
Cell death
pigments
19 Citations (Scopus)

The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation

Liu, X., Ward, K., Xavier, C., Jann, J., Clark, A., Pang, I-H. & Wu, H., 1 Aug 2016, In : Redox Biology. 8, p. 98-109 12 p.

Research output: Contribution to journalArticleResearchpeer-review

NF-E2-Related Factor 2
Retinal Pigments
Epithelial Cells
Chemical activation
Oxidative stress
4 Citations (Scopus)

Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues

Upadhyaya, B., Tian, X., Wu, H. & Lou, M. F., 1 Jan 2015, In : Experimental Eye Research. 130, p. 58-65 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glutaredoxins
Sulfhydryl Compounds
Ciliary Body
Swine
Lenses