Personal profile
Area of Expertise
I study ion channels in the smooth muscle cells of coronary arteries and arterioles. I am especially interested in how these ion channels regulate vascular tone and control coronary blood flow. I am trying to determine how these mechanism work on a beat-to-beat basis in the normal heart as well as what goes wrong over the long-term with obesity, diabetes, and other pathological conditions. My goal is to provide a better understanding of coronary vascular regulation in health and disease.
Education/Academic qualification
BS, Physiology, Oklahoma State University
PhD, Physiology, Univ. of Missouri
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mineralocorticoid Receptor-Dependent Coronary Vascular Dysfunction in Obesity
Tune, J. (PI) & Dick, G. (CoI)
University of Missouri-Columbia
1/06/20 → 30/11/22
Project: Research
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MENTORING IN CARDIOVASCULAR BIOLOGY
Dick, G. (PI), KAPUSTA, D. (PI), BOULARES, H. (PI), PARK, F. (PI), CATLING, A. (PI), WU, G. (PI), LANIER, S. (PI), SONGU-MIZE, E. (PI), STRONG, J. (PI) & VARNER, K. (PI)
1/07/06 → 30/06/07
Project: Research
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Functional Adaptations in Coronary Reactivity following Healthy Pregnancy in Swine
Tucker, S. M., Essajee, S. I., Warne, C. M., Dick, G. M., Goulopoulou, S. & Tune, J. D., 1 Mar 2025, In: Journal of Vascular Research. 62, 2, p. 78-87 10 p.Research output: Contribution to journal › Article › peer-review
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Potassium as an electro-metabolic signal for local coronary vasodilation
Tune, J. D., Duncker, D. J., Goodwill, A. G., Warne, C. M., Essajee, S. I., Tucker, S. M., Romero, S. A., Bender, S. B., Beard, D. A., Figueroa, C. A., Sorop, O., Merkus, D. & Dick, G. M., Aug 2025, In: Basic Research in Cardiology. 120, 4, p. 815-833 19 p.Research output: Contribution to journal › Article › peer-review
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Unraveling the Gordian knot of coronary pressure-flow autoregulation
Tune, J. D., Warne, C. M., Essajee, S. I., Tucker, S. M., Figueroa, C. A., Dick, G. M. & Beard, D. A., May 2024, In: Journal of Molecular and Cellular Cardiology. 190, p. 82-91 10 p.Research output: Contribution to journal › Review article › peer-review
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Heart of the matter: Coronary dysfunction in metabolic syndrome
Berwick, Z. C., Dick, G. M. & Tune, J. D., Apr 2012, In: Journal of Molecular and Cellular Cardiology. 52, 4, p. 848-856 9 p.Research output: Contribution to journal › Review article › peer-review
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Oxygen-sensing pathways below autoregulatory threshold act to sustain myocardial oxygen delivery during reductions in perfusion pressure
Warne, C. M., Essajee, S. I., Tucker, S. M., Figueroa, C. A., Beard, D. A., Dick, G. M. & Tune, J. D., Dec 2023, In: Basic Research in Cardiology. 118, 1, 12.Research output: Contribution to journal › Article › peer-review