• 584 Citations
  • 15 h-Index
19952020

Research output per year

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Personal profile

Area of Expertise

My laboratory focuses on the development of research/therapeutic strategies to slow premature brain aging resulting from a chronic use of drugs of dependence such as benzodiazepine (BZD, an antianxiety medication) and alcohol, and withdrawal stress from the substances.
Currently, we investigate whether BZD administration to mice elevates/alters the production of neurotoxic amyloid beta, amyloid beta-producing gamma-secretase, and peripheral BZD receptors. We also investigate whether these changes mediate aging-like behavioral signs such as movement and cognition deficits. We are planning to test whether the aging-like effects of BZD will be attenuated by training mice with moderately low oxygen. Our study may help understand how to minimize accelerated brain aging associated with substance misuse.

Education/Academic qualification

PhD in Pharmacology, UNT Health Science Center

Award Date: 1 Jan 2003

MS in Pharmacology, UNT Health Science Center

Award Date: 1 Jan 2002

MS in Pharmacy, Ewha University

Award Date: 1 Jan 2001

BS in Pharmacy, Ewha University

Award Date: 1 Jan 2000

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Projects

Research Output

  • 584 Citations
  • 15 h-Index
  • 34 Article
  • 4 Review article
  • 1 Short survey
  • Chronic benzodiazepine suppresses translocator protein and elevates amyloid β in mice

    Tan, S., Metzger, D. B. & Jung, M. E., Sep 2018, In : Pharmacology Biochemistry and Behavior. 172, p. 59-67 9 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations
  • 4 Scopus citations
  • 6 Scopus citations

    A sex difference in oxidative stress and behavioral suppression induced by ethanol withdrawal in rats

    Jung, M. E. & Metzger, D. B., 1 Nov 2016, In : Behavioural Brain Research. 314, p. 199-214 16 p.

    Research output: Contribution to journalArticle

  • 10 Scopus citations