Projects per year
Personal profile
Area of Expertise
The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service
Education/Academic qualification
BS in Microbiology, Huazhong Agricultural University
MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences
PhD in Botany & Microbiology, Michigan State University
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Collaborations and top research areas from the last five years
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Projects
- 7 Finished
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High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research
Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)
27/01/17 → 31/01/18
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI)
NCI: National Cancer Institute
1/06/13 → 31/05/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI), CHENG, Y.-Q. (PI), CHENG, Y. (PI), CHENG, Y. (PI) & CHENG, Y.-Q. (PI)
1/08/10 → 30/11/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
CHENG, Y. (PI), CHENG, Y.-Q. (CoPI) & Cheng, E. Y. (CoPI)
1/08/10 → 30/11/15
Project: Research
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Novel features of the polysaccharide-digesting gliding bacterium Flavobacterium johnsoniae as revealed by genome sequence analysis
McBride, M. J., Xie, G., Martens, E. C., Lapidus, A., Henrissat, B., Rhodes, R. G., Goltsman, E., Wang, W., Xu, J., Hunnicutt, D. W., Staroscik, A. M., Hoover, T. R., Cheng, Y. Q. & Stein, J. L., Nov 2009, In: Applied and Environmental Microbiology. 75, 21, p. 6864-6875 12 p.Research output: Contribution to journal › Article › peer-review
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Corrigendum to: Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment [Surgery. 2020 Jan;167(1):189-196. doi: 10.1016/j.surg.2019.05.092. Epub 2019 Oct 16.PMID: 31629542] (Surgery (2020) 167(1) (189–196), (S0039606019305835), (10.1016/j.surg.2019.05.092))
Guenter, R., Aweda, T., Carmona Matos, D. M., Jang, S., Whitt, J., Cheng, Y. Q., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., Jul 2021, In: Surgery (United States). 170, 1, p. 351 1 p.Research output: Contribution to journal › Comment/debate
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Structural determinants stabilizing the axial channel of ClpP for substrate translocation
Alexopoulos, J., Ahsan, B., Homchaudhuri, L., Husain, N., Cheng, Y. Q. & Ortega, J., Oct 2013, In: Molecular Microbiology. 90, 1, p. 167-180 14 p.Research output: Contribution to journal › Article › peer-review
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Production of Thailandepsin a from burkholderia thailandensis E264/pBMTL3-tdpR fermentation
Hui, J. Y., Wang, W., Cheng, Y. Q. & Zhang, X. H., 1 Jun 2015, In: Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities. 29, 3, p. 593-599 7 p.Research output: Contribution to journal › Article › peer-review
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Origin and bioactivities of thiosulfinated FK228
Liu, X., Currens, G. C., Xue, L. & Cheng, Y. Q., 2019, In: MedChemComm. 10, 4, p. 538-542 5 p.Research output: Contribution to journal › Article › peer-review