Projects per year
Personal profile
Area of Expertise
The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service
Education/Academic qualification
BS in Microbiology, Huazhong Agricultural University
MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences
PhD in Botany & Microbiology, Michigan State University
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- 6 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 7 Finished
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High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research
Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)
27/01/17 → 31/01/18
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI)
NCI: National Cancer Institute
1/06/13 → 31/05/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
CHENG, Y. (PI), CHENG, Y.-Q. (CoPI) & Cheng, E. Y. (CoPI)
1/08/10 → 30/11/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI), CHENG, Y.-Q. (PI), CHENG, Y. (PI), CHENG, Y. (PI) & CHENG, Y.-Q. (PI)
1/08/10 → 30/11/15
Project: Research
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FK228 from Burkholderia thailandensis MSMB43
Liu, X. Y., Wang, C. & Cheng, Y. Q., Sep 2012, In: Acta Crystallographica Section E: Structure Reports Online. 68, 9, p. o2757-o2758Research output: Contribution to journal › Article › peer-review
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Origin and bioactivities of thiosulfinated FK228
Liu, X., Currens, G. C., Xue, L. & Cheng, Y. Q., 2019, In: MedChemComm. 10, 4, p. 538-542 5 p.Research output: Contribution to journal › Article › peer-review
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Polyketide biosynthesis beyond the type I, II, and III polyketide synthase paradigms: A progress report
Shen, B., Cheng, Y. Q., Christenson, S. D., Jiang, H., Ju, J., Kwon, H. J., Lim, S. K., Liu, W., Nonaka, K., Seo, J. W., Smith, W. C., Standage, S., Tang, G. L., Van Lanen, S. & Zhang, J., 2007, Polyketides Biosynthesis, Biological Activity, and Genetic Engineering. Rimando, A. & Baerson, S. (eds.). p. 154-166 13 p. (ACS Symposium Series; vol. 955).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Cyclo(-l-prolyl-l-valinyl-) from Burkholderia thailandensis MSMB43
Liu, X. Y., Wang, C. & Cheng, Y. Q., Nov 2012, In: Acta Crystallographica Section E: Structure Reports Online. 68, 11, p. o3182-o3183Research output: Contribution to journal › Article › peer-review
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A putative branched-chain-amino-acid transaminase gene required for HC-toxin biosynthesis and pathogenicity in Cochliobolus carbonum
Cheng, Y. Q., Ahn, J. H. & Walton, J. D., Dec 1999, In: Microbiology. 145, 12, p. 3539-3546 8 p.Research output: Contribution to journal › Article › peer-review