Projects per year
Personal profile
Area of Expertise
The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service
Education/Academic qualification
BS in Microbiology, Huazhong Agricultural University
MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences
PhD in Botany & Microbiology, Michigan State University
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 7 Finished
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High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research
Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)
27/01/17 → 31/01/18
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI)
NCI: National Cancer Institute
1/06/13 → 31/05/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
CHENG, Y. (PI), CHENG, Y.-Q. (CoPI) & Cheng, E. Y. (CoPI)
1/08/10 → 30/11/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI), CHENG, Y.-Q. (PI), CHENG, Y. (PI), CHENG, Y. (PI) & CHENG, Y.-Q. (PI)
1/08/10 → 30/11/15
Project: Research
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13C labeling indicates that the epoxide-containing amino acid of HC- toxin is biosynthesized by head-to-tail condensation of acetate
Cheng, Y. Q., Le, L. D., Walton, J. D. & Bishop, K. D., 1999, In: Journal of Natural Products. 62, 1, p. 143-145 3 p.Research output: Contribution to journal › Article › peer-review
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Leinamycin Biosynthesis Revealing Unprecedented Architectural Complexity for a Hybrid Polyketide Synthase and Nonribosomal Peptide Synthetase
Tang, G. L., Cheng, Y. Q. & Shen, B., Jan 2004, In: Chemistry and Biology. 11, 1, p. 33-45 13 p.Research output: Contribution to journal › Article › peer-review
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Corrigendum to: Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment [Surgery. 2020 Jan;167(1):189-196. doi: 10.1016/j.surg.2019.05.092. Epub 2019 Oct 16.PMID: 31629542] (Surgery (2020) 167(1) (189–196), (S0039606019305835), (10.1016/j.surg.2019.05.092))
Guenter, R., Aweda, T., Carmona Matos, D. M., Jang, S., Whitt, J., Cheng, Y. Q., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., Jul 2021, In: Surgery (United States). 170, 1, p. 351 1 p.Research output: Contribution to journal › Comment/debate
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KE108-conjugated unimolecular micelles loaded with a novel HDAC inhibitor thailandepsin-A for targeted neuroendocrine cancer therapy
Chen, G., Jaskula-Sztul, R., Harrison, A., Dammalapati, A., Xu, W., Cheng, Y., Chen, H. & Gong, S., 1 Aug 2016, In: Biomaterials. 97, p. 22-33 12 p.Research output: Contribution to journal › Article › peer-review
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The ADEP biosynthetic gene cluster in Streptomyces hawaiiensis NRRL 15010 reveals an accessory clpP gene as a novel antibiotic resistance factor
Thomy, D., Culp, E., Adamek, M., Cheng, E. Y., Ziemert, N., Wright, G. D., Sass, P. & Brötz-Oesterhelt, H., 2019, In: Applied and Environmental Microbiology. 85, 20, e01292-19.Research output: Contribution to journal › Article › peer-review