Projects per year
Personal profile
Area of Expertise
The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service
Education/Academic qualification
BS in Microbiology, Huazhong Agricultural University
MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences
PhD in Botany & Microbiology, Michigan State University
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research
Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)
27/01/17 → 31/01/18
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI)
NCI: National Cancer Institute
1/06/13 → 31/05/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI), CHENG, Y.-Q. (PI), CHENG, Y. (PI), CHENG, Y. (PI) & CHENG, Y.-Q. (PI)
1/08/10 → 30/11/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
CHENG, Y. (PI), CHENG, Y.-Q. (CoPI) & Cheng, E. Y. (CoPI)
1/08/10 → 30/11/15
Project: Research
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New insights into the genetic organization of the FK228 biosynthetic gene cluster in chromobacterium violaceum No. 968
Potharla, V. Y., Wesener, S. R. & Cheng, Y. Q., Feb 2011, In: Applied and Environmental Microbiology. 77, 4, p. 1508-1511 4 p.Research output: Contribution to journal › Article › peer-review
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Thailandepsin A
Wang, C. & Cheng, Y. Q., Nov 2011, In: Acta Crystallographica Section E: Structure Reports Online. 67, 11, p. o2948-o2949Research output: Contribution to journal › Article › peer-review
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Minimum Information about a Biosynthetic Gene cluster
Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., De Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A. & Hadjithomas, M. & 134 others, , 18 Aug 2015, In: Nature Chemical Biology. 11, 9, p. 625-631 7 p.Research output: Contribution to journal › Review article › peer-review
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KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression
Wei, H., Ma, W., Lu, X., Liu, H., Lin, K., Wang, Y., Ye, Z., Sun, L., Huang, Z., Pan, T., Zhou, Z., Cheng, E. Y., Zhang, H., Gao, P. & Zhong, X., Sep 2021, In: Cancer Communications. 41, 9, p. 904-920 17 p.Research output: Contribution to journal › Article › peer-review
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A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis
Cheng, Y. Q. & Walton, J. D., 18 Feb 2000, In: Journal of Biological Chemistry. 275, 7, p. 4906-4911 6 p.Research output: Contribution to journal › Article › peer-review