Projects per year
Personal profile
Area of Expertise
The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service
Education/Academic qualification
BS in Microbiology, Huazhong Agricultural University
MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences
PhD in Botany & Microbiology, Michigan State University
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Collaborations and top research areas from the last five years
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Projects
- 7 Finished
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High-Resolution Tandem Mass Spectrometer for Advanced Biomolecular Research
Prokai, L. (PI), Forster, M. (CoI) & Cheng, E. Y. (CoI)
27/01/17 → 31/01/18
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI)
NCI: National Cancer Institute
1/06/13 → 31/05/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
Cheng, E. Y. (PI), CHENG, Y.-Q. (PI), CHENG, Y. (PI), CHENG, Y. (PI) & CHENG, Y.-Q. (PI)
1/08/10 → 30/11/15
Project: Research
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Discover and Engineer New Histone Deacetylase Inhibitors as Anticancer Agents
CHENG, Y. (PI), CHENG, Y.-Q. (CoPI) & Cheng, E. Y. (CoPI)
1/08/10 → 30/11/15
Project: Research
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Developing new targeting strategy for androgen receptor variants in castration resistant prostate cancer
Wang, B., Lo, U. G., Wu, K., Kapur, P., Liu, X., Huang, J., Chen, W., Hernandez, E., Santoyo, J., Ma, S. H., Pong, R. C., He, D., Cheng, Y. Q. & Hsieh, J. T., 15 Nov 2017, In: International Journal of Cancer. 141, 10, p. 2121-2130 10 p.Research output: Contribution to journal › Article › peer-review
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Genomics-guided discovery of thailanstatins A, B, and C as pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43
Liu, X., Biswas, S., Berg, M. G., Antapli, C. M., Xie, F., Wang, Q., Tang, M. C., Tang, G. L., Zhang, L., Dreyfuss, G. & Cheng, Y. Q., 26 Apr 2013, In: Journal of Natural Products. 76, 4, p. 685-693 9 p.Research output: Contribution to journal › Article › peer-review
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Genomics-guided discovery of a new and significantly better source of anticancer natural drug FK228
Liu, X., Xie, F., Doughty, L. B., Wang, Q., Zhang, L., Liu, X. & Cheng, Y. Q., Dec 2018, In: Synthetic and Systems Biotechnology. 3, 4, p. 268-274 7 p.Research output: Contribution to journal › Article › peer-review
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Thailandepsins: Bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities
Wang, C., Henkes, L. M., Doughty, L. B., He, M., Wang, D., Meyer-Almes, F. J. & Cheng, Y. Q., 28 Oct 2011, In: Journal of Natural Products. 74, 10, p. 2031-2038 8 p.Research output: Contribution to journal › Article › peer-review
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New insights into the genetic organization of the FK228 biosynthetic gene cluster in chromobacterium violaceum No. 968
Potharla, V. Y., Wesener, S. R. & Cheng, Y. Q., Feb 2011, In: Applied and Environmental Microbiology. 77, 4, p. 1508-1511 4 p.Research output: Contribution to journal › Article › peer-review