Projects per year
Personal profile
Area of Expertise
My laboratory research focuses on the development of strategies for neuroprotection in glaucoma. Specifically, we are testing various small molecules and adeno-associated viral gene therapies for their ability to attenuate neurodegeneration in animal models of glaucoma. We also aim to unravel cellular and molecular mechanisms underlying the pathophysiology of glaucoma.
Concepts/techniques: We carry out these studies using in vitro rat primary retinal ganglion cell cultures, ex vivo adult rat retinal explants, and various in vivo rodent models of glaucoma. We use visual function tests including pattern ERG and optomotor test to determine the efficacy of clinically relevant experimental pharmacotherapies.
Our ongoing studies have the potential to develop novel therapeutic agents for neuroprotection in glaucoma.
Education/Academic qualification
MS in Biochemistry & Genetics, University of Lodz
PhD in Microbiology, University of Lodz
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Mechanisms Underlying Endothel
Krishnamoorthy, R. (PI), Stankowska, D. (CoI), Inman, D. (CoI) & Clark, A. (CoI)
1/06/21 → 31/08/26
Project: Research
-
Sex differences in in vitro and in vivo glaucoma models may predict gender specific dose adjustment needs
Stankowska, D. (PI)
1/03/20 → 31/08/25
Project: Research
-
-
Novel hybrid molecule with both IOP lowering and neuroprotective effects for treatment of glaucoma
Stankowska, D. (CoPI) & ACHARYA, S. (PI)
1/09/20 → 31/08/21
Project: Research
-
Novel hybrid molecule with both IOP lowering and neuroprotective effects for treatment of glaucoma
ACHARYA, S. (PI), Stankowska, D. (CoPI), ACHARYA, S. (CoPI) & Stankowska, D. (CoPI)
1/09/20 → 31/08/24
Project: Research
-
The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability
Shetty, S., Padijnayayveetil, J., Tucker, T., Stankowska, D. & Idell, S., Dec 2008, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 295, 6, p. L967-L975Research output: Contribution to journal › Review article › peer-review
-
Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells
Wang, Y., Ding, M., Chaudhari, S., Ding, Y., Yuan, J., Stankowska, D., He, S., Krishnamoorthy, R., Cunningham, J. T. & Ma, R., 3 May 2013, In: Journal of Biological Chemistry. 288, 18, p. 12852-12865 14 p.Research output: Contribution to journal › Article › peer-review
-
Mycobacterium tuberculosis origin of replication and the promoter for immunodominant secreted antigen 85B are the targets of MtrA, the essential response regulator
Rajagopalan, M., Dziedzic, R., Al Zayer, M., Stankowska, D., Ouimet, M. C., Bastedo, D. P., Marczynski, G. T. & Madiraju, M. V., 21 May 2010, In: Journal of Biological Chemistry. 285, 21, p. 15816-15827 12 p.Research output: Contribution to journal › Article › peer-review
-
Mycobacterium tuberculosis mtrA merodiploid strains with point mutations in the signal-receiving domain of MtrA exhibit growth defects in nutrient broth
Al Zayer, M., Stankowska, D., Dziedzic, R., Sarva, K., Madiraju, M. V. & Rajagopalan, M., May 2011, In: Plasmid. 65, 3, p. 210-218 9 p.Research output: Contribution to journal › Article › peer-review
-
Systemy komunikacji miȩdzykomórkowej bakterii gram-ujemnych i ich znaczenie w ekspresji cech fenotypowych
Stańkowska, D. & Kaca, W., 2005, In: Postepy Mikrobiologii. 44, 2, p. 99-111 13 p.Research output: Contribution to journal › Review article › peer-review