• 1604 Citations
  • 20 h-Index
19952020

Research output per year

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Research Output

  • 1604 Citations
  • 20 h-Index
  • 34 Article
  • 8 Review article
  • 1 Editorial
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Article
2018

Atrophied thymus, a tumor reservoir for harboring melanoma cells

Sizova, O., Kuriatnikov, D., Liu, Y. & Su, D. M., Nov 2018, In : Molecular Cancer Research. 16, 11, p. 1652-1664 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Extracellular vesicles extracted from young donor serum attenuate inflammaging via partially rejuvenating aged T-cell immunotolerance

Wang, W., Wang, L., Ruan, L., Oh, J., Dong, X., Zhuge, Q. & Su, D. M., Nov 2018, In : FASEB Journal. 32, 11, p. 5899-5912 14 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

A fine-tune role of Mir-125a-5p on Foxn1 during age-associated changes in the thymus

Xu, M., Sizova, O., Wang, L. & Su, D. M., 1 Jan 2017, In : Aging and Disease. 8, 3, p. 277-286 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Capacity of tTreg generation is not impaired in the atrophied thymus

Oh, J., Wang, W., Thomas, R. & Su, D. M., 8 Nov 2017, In : PLoS Biology. 15, 11, e2003352.

Research output: Contribution to journalArticle

9 Scopus citations

Soluble antigens from the neurotropic pathogen Angiostrongylus cantonensis directly induce thymus atrophy in a mouse model

Liu, Z., Su, D. M., Yu, Z. L., Wu, F., Liu, R. F., Luo, S. Q., Lv, Z. Y., Zeng, X., Sun, X. & Wu, Z. D., 1 Jan 2017, In : Oncotarget. 8, 30, p. 48575-48590 16 p.

Research output: Contribution to journalArticle

2015

Cross-talk between human neural stem/progenitor cells and peripheral blood mononuclear cells in an allogeneic co-culture model

Zhang, H., Shao, B., Zhuge, Q., Wang, P., Zheng, C., Huang, W., Yang, C., Wang, B., Su, D. M. & Jin, K., 6 Feb 2015, In : PLoS ONE. 10, 2, e0117432.

Research output: Contribution to journalArticle

3 Scopus citations

Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation

Coder, B. D., Wang, H., Ruan, L. & Su, D. M., 15 Jun 2015, In : Journal of Immunology. 194, 12, p. 5825-5837 13 p.

Research output: Contribution to journalArticle

30 Scopus citations
2014

Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice

Ruan, L., Zhang, Z., Mu, L., Burnley, P., Wang, L., Coder, B., Zhuge, Q. & Su, D. M., 1 Jan 2014, In : Cell Death and Disease. 5, 10, e1457.

Research output: Contribution to journalArticle

9 Scopus citations

MTOR Signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia

Xie, L., Sun, F., Wang, J., Mao, X. O., Xie, L., Yang, S. H., Su, D. M., Simpkins, J. W., Greenberg, D. A. & Jin, K., 15 Jun 2014, In : Journal of Immunology. 192, 12, p. 6009-6019 11 p.

Research output: Contribution to journalArticle

90 Scopus citations

Timing and Dose Regimens of Marrow Mesenchymal Stem Cell Transplantation Affect the Outcomes and Neuroinflammatory Response After Ischemic Stroke

Wang, L. Q., Lin, Z. Z., Zhang, H. X., Shao, B., Xiao, L., Jiang, H. G., Zhuge, Q. C., Xie, L. K., Wang, B., Su, D. M. & Jin, K. L., Apr 2014, In : CNS Neuroscience and Therapeutics. 20, 4, p. 317-326 10 p.

Research output: Contribution to journalArticle

35 Scopus citations
2013

Role of the p63-FoxN1 regulatory axis in thymic epithelial cell homeostasis during aging

Burnley, P., Rahman, M., Wang, H., Zhang, Z., Sun, X., Zhuge, Q. & Su, D. M., 1 Nov 2013, In : Cell Death and Disease. 4, 11, e932.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Age-related disruption of steady-state thymic medulla provokes autoimmune phenotype via perturbing negative selection

Xia, J., Wang, H., Guo, J., Zhang, Z., Coder, B. & Su, D. M., 1 Jan 2012, In : Aging and Disease. 3, 3, p. 248-259 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus

Sun, L., Brown, R., Chen, S., Zhuge, Q. & Su, D. M., 1 Jan 2012, In : Aging. 4, 9, p. 606-619 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to infection and mimics changes of aging

Guo, J., Feng, Y., Barnes, P., Huang, F. F., Idell, S., Su, D. M. & Shams, H., 13 Apr 2012, In : PLoS ONE. 7, 4, e34681.

Research output: Contribution to journalArticle

16 Scopus citations

Insights on Foxn1 biological significance and usages of the "nude" mouse in studies of T-Lymphopoiesis

Zhang, Z., Burnley, P., Coder, B. & Su, D. M., 24 Sep 2012, In : International Journal of Biological Sciences. 8, 8, p. 1156-1167 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Intraperitoneal injection of JNK-specific inhibitor SP600125 inhibits the expression of presenilin-1 and Notch signaling in mouse brain without induction of apoptosis

Rahman, M., Zhang, Z., Mody, A. A., Su, D. M. & Das, H. K., 11 Apr 2012, In : Brain Research. 1448, p. 117-128 12 p.

Research output: Contribution to journalArticle

21 Scopus citations
2011

Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium

Guo, J., Rahman, M., Cheng, L., Zhang, S., Tvinnereim, A. & Su, D. M., 1 Mar 2011, In : Journal of Molecular Medicine. 89, 3, p. 263-277 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2010

A new avenue to cure cancer by turning adaptive immune T cells to innate immune NK cells via reprogramming

Su, D. M. & Vankayalapati, R., 1 Dec 2010, In : Journal of Molecular Cell Biology. 2, 5, p. 237-239 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution

Sun, L., Guo, J., Brown, R., Amagai, T., Zhao, Y. & Su, D. M., 1 Jun 2010, In : Aging cell. 9, 3, p. 347-357 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy

Cheng, L., Guo, J., Sun, L., Fu, J., Barnes, P. F., Metzger, D., Chambon, P., Oshima, R. G., Amagai, T. & Su, D. M., 19 Feb 2010, In : Journal of Biological Chemistry. 285, 8, p. 5836-5847 12 p.

Research output: Contribution to journalArticle

69 Scopus citations
2008

Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis

Zhang, P., Su, D. M., Liang, M. & Fu, J., 1 Mar 2008, In : Molecular Immunology. 45, 5, p. 1470-1476 7 p.

Research output: Contribution to journalArticle

142 Scopus citations

T cell development from kit-negative progenitors in the Foxn1 Δ/Δ mutant thymus

Xiao, S., Su, D. M. & Manley, N. R., 15 Jan 2008, In : Journal of Immunology. 180, 2, p. 914-921 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2007

Atypical memory phenotype T cells with low homeostatic potential and impaired TCR signaling and regulatory T cell function in Foxn1 Δ/Δ mutant mice

Xiao, S., Su, D. M. & Manley, N. R., 15 Dec 2007, In : Journal of Immunology. 179, 12, p. 8153-8163 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution

Zhu, X., Gui, J., Dohkan, J., Cheng, L., Barnes, P. F. & Su, D. M., 1 Oct 2007, In : Aging Cell. 6, 5, p. 663-672 10 p.

Research output: Contribution to journalArticle

64 Scopus citations

Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus

Gordon, J., Xiao, S., Hughes, B., Su, D. M., Navarre, S. P., Condie, B. G. & Manley, N. R., 11 Jul 2007, In : BMC Developmental Biology. 7, 69.

Research output: Contribution to journalArticle

69 Scopus citations

The aged thymus shows normal recruitment of lymphohematopoietic progenitors but has defects in thymic epithelial cells

Gui, J., Zhu, X., Dohkan, J., Cheng, L., Barnes, P. F. & Su, D. M., 1 Oct 2007, In : International Immunology. 19, 10, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

70 Scopus citations
2005

Ontogeny and regulation of IL-7-expressing thymic epithelial cells

Zamisch, M., Moore-Scott, B., Su, D. M., Lucas, P. J., Manley, N. & Richie, E. R., 1 Jan 2005, In : Journal of Immunology. 174, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

89 Scopus citations
2003

A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation

Su, D. M., Navarre, S., Oh, W. J., Condie, B. G. & Manley, N. R., 1 Nov 2003, In : Nature Immunology. 4, 11, p. 1128-1135 8 p.

Research output: Contribution to journalArticle

119 Scopus citations
2002
14 Scopus citations
2001

Hoxa3 and Pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis

Su, D. M., Ellis, S., Napier, A., Lee, K. & Manley, N. R., 15 Aug 2001, In : Developmental Biology. 236, 2, p. 316-329 14 p.

Research output: Contribution to journalArticle

113 Scopus citations

γ-Secretase inhibitors repress thymocyte development

Hadland, B. K., Manley, N. R., Su, D. M., Longmore, G. D., Moore, C. L., Wolfe, M. S., Schroeter, E. H. & Kopan, R., 19 Jun 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 13, p. 7487-7491 5 p.

Research output: Contribution to journalArticle

181 Scopus citations
2000

Hoxa3 and Pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development

Su, D. M. & Manley, N. R., 1 Jan 2000, In : Journal of Immunology. 164, 11, p. 5753-5760 8 p.

Research output: Contribution to journalArticle

59 Scopus citations
1997

Interferons α/β inhibit IL-7-induced proliferation of CD4- CD8- CD3- CD44+ CD25+ thymocytes, but do not inhibit that of CD4- CD8- CD3- CD44- CD25- thymocytes

Su, D. M., Wang, J., Lin, Q., Cooper, M. D. & Watanabe, T., 1 Jan 1997, In : Immunology. 90, 4, p. 543-549 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
1995

A novel cell surface antigen, immature thymocyte antigen-1, is involved in the differentiation of murine thymocytes

Kishi, H., Su, D. M., Muraguchi, A. & Watanabe, T., 1 Jan 1995, In : Journal of Immunology. 155, 2, p. 568-577 10 p.

Research output: Contribution to journalArticle

13 Scopus citations