Projects per year
Personal profile
Research Interests
Corneal pathobiology, Keratoconus, Diabetic Keratopathy, Sphingolipids, and 3D bioprinting
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Area of Expertise
Dr Karamichos research aims to discover, develop, and deliver novel therapies for the treatment of corneal trauma, diseases, and dystrophies. Dr Karamichos and team focus part of their work on Keratoconus disease where they are working on novel biomarkers and delineating the role of sex hormones during the onset and progression of the disease. Dr Karamichos is also investigating the role of sphingolipids in corneal wound healing, using complementary in vitro and in vivo models. Other areas of investigation are focused on diabetic keratopathy and the application of bioengineering for corneal transplantation.
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Collaborations and top research areas from the last five years
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The Impact of Prolactin Induced Protein in Corneal Wound Healing and Fibrosis
Ma, J. X. (CoPI) & Karamichos, D. (PI)
30/09/23 → 28/02/25
Project: Research
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The Intimate Interplay Between Keratoconus, Sex Hormones, and the Anterior Pituitary
Karamichos, D. (PI)
1/09/23 → 31/01/25
Project: Research
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Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling
Liang, W., Huang, L., Ma, X., Dong, L., Cheng, R., Dehdarani, M., Karamichos, D. & Ma, J. X., Apr 2022, In: Diabetes. 71, 4, p. 747-761 15 p.Research output: Contribution to journal › Article › peer-review
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A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy
Liang, W., Huang, L., Yuan, T., Cheng, R., Takahashi, Y., Moiseyev, G. P., Karamichos, D. & Ma, J. X., Aug 2023, In: Investigative Ophthalmology and Visual Science. 64, 11, 33.Research output: Contribution to journal › Article › peer-review
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3D stacked construct: A novel substitute for corneal tissue engineering
Priyadarsini, S., Nicholas, S. E. & Karamichos, D., 2018, Methods in Molecular Biology. Humana Press Inc., p. 173-180 8 p. (Methods in Molecular Biology; vol. 1697).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment
Brown, M. E., Montgomery, M. L., Kamath, M. M., Nicholas, S., Liu, Y., Karamichos, D. & Fuller, K. K., Jun 2021, In: Experimental eye research. 207, 108581.Research output: Contribution to journal › Article › peer-review
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Growth factor regulation of corneal keratocyte differentiation and migration in compressed collagen matrices
Kim, A., Lakshman, N., Karamichos, D. & Matthew Petroll, W., Feb 2010, In: Investigative Ophthalmology and Visual Science. 51, 2, p. 864-875 12 p.Research output: Contribution to journal › Article › peer-review