Personal profile
Research Interests
Stroke, Traumatic Brain injury, metabolic syndrome, Alzheimer’s disease, steroids, drug discovery
Area of Expertise
My laboratory is interested in identifying treatments for brain injury resulting from stroke, traumatic brain injury, Alzheimer Disease, and metabolic syndrome. We are particularly interested in identifying early points of intervention to reduce or prevent progression of disease. Previous studies have focused on steroid hormones and plant estrogens and current projects are focused on using novel compounds to protect and regenerate brain tissue after stroke and traumatic brain injury.
Techniques
In vivo and in vitro models of stoke, traumatic brain injury, metabolic syndrome, Alzheimer Disease; immunostaining, western blotting, PCR, fluorescent imaging, ELISA, animal behavior, gene expression, MRI.
Education/Academic qualification
BS in Biology, Emory University
PhD in Neuroscience, University of Pittsburgh
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Collaborations and top research areas from the last five years
Projects
- 21 Finished
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Early Interventions to Reduce the Effect of Metabolic Syndrome on Brain Health
Schreihofer, D. (PI)
13/03/23 → 12/03/24
Project: Research
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Discovery of Functionally Sele
Luedtke, R. (PI) & Schreihofer, D. (PI)
NIA: National Institute on Aging
15/09/17 → 31/05/25
Project: Research
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Brain Stem Mechanisms for Altered Autonomic Regulation of Blood Pressure in Obesity
Schreihofer, A. (PI), Sumien, N. (CoI) & Schreihofer, D. (CoI)
NHLBI: Nat Heart, Lung & Blood Institute
1/07/17 → 31/08/23
Project: Research
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Beneficial Effects of Dietary Soy Phytoestrogens on the Aging Female Brain
Schreihofer, D. (PI)
1/08/16 → 31/12/19
Project: Research
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Sigma 1 Receptor as a Target for Repetitive Concussive Brain Injury
Schreihofer, D. (PI), Luedtke, R. (CoI) & Sumien, N. (CoI)
1/08/16 → 31/08/20
Project: Research
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The authors reply
Quaynor, S. D., Schreihofer, D. A. & Layman, L. C., 2013, In: New England Journal of Medicine. 369, 17, p. 1664 1 p.Research output: Contribution to journal › Letter › peer-review
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Suppression of luteinizing hormone secretion during short-term fasting in male rhesus monkeys: The role of metabolic versus stress signals
Schreihofer, D. A., Parfitt, D. B. & Cameron, J. L., May 1993, In: Endocrinology. 132, 5, p. 1881-1889 9 p.Research output: Contribution to journal › Article › peer-review
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Adaptive cerebral neovascularization in a model of type 2 diabetes: Relevance to focal cerebral ischemia
Li, W., Prakash, R., Kelly-Cobbs, A. I., Ogbi, S., Kozak, A., El-Remessy, A. B., Schreihofer, D. A., Fagan, S. C. & Ergul, A., Jan 2010, In: Diabetes. 59, 1, p. 228-235 8 p.Research output: Contribution to journal › Article › peer-review
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Feeding-induced stimulation of luteinizing hormone secretion in male rhesus monkeys is not dependent on a rise in blood glucose concentration
Schreihofer, D. A., Renda, F. & Cameron, J. L., 1996, In: Endocrinology. 137, 9, p. 3770-3776 7 p.Research output: Contribution to journal › Article › peer-review
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Hypoxia-inducible factor and vascular endothelial growth factor are targets of dietary soy during acute stroke in female rats
Ma, Y., Lovekamp-Swan, T., Bekele, W., Dohi, A. & Schreihofer, D. A., 1 Apr 2013, In: Endocrinology. 154, 4, p. 1589-1597 9 p.Research output: Contribution to journal › Article › peer-review