Projects per year
Personal profile
Research Interests
Neurodegeneration, Glaucoma, Metabolism, Mitochondria
URL
Area of Expertise
My laboratory investigates the mechanisms of glaucoma, with an emphasis on how neurons and glial cells interact during the process of degeneration. Our research has implicated metabolism in the pathogenesis of glaucoma, finding that transfer of energy substrate is compromised and mitochondria are dysfunctional prior to axon loss. These observations offer new targets for therapeutic development.
Education/Academic qualification
BS in Biology, Drexel University
PhD in Neuroscience, University of Virginia
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Dive into the research topics where Denise Inman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanisms Underlying Endothel
Krishnamoorthy, R. (PI), Stankowska, D. (CoI), Inman, D. (CoI) & Clark, A. (CoI)
1/06/21 → 31/08/26
Project: Research
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Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma
Inman, D. M., Sappington, R. M., Horner, P. J. & Calkins, D. J., Mar 2006, In: Investigative Ophthalmology and Visual Science. 47, 3, p. 986-996 11 p.Research output: Contribution to journal › Article › peer-review
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Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma
Steele, M. R., Inman, D. M., Calkins, D. J., Horner, P. J. & Vetter, M. L., Mar 2006, In: Investigative Ophthalmology and Visual Science. 47, 3, p. 977-985 9 p.Research output: Contribution to journal › Article › peer-review
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Ocular Inflammation and Oxidative Stress as a Result of Chronic Intermittent Hypoxia: A Rat Model of Sleep Apnea
Donkor, N., Gardner, J. J., Bradshaw, J. L., Cunningham, R. L. & Inman, D. M., Jul 2024, In: Antioxidants. 13, 7, 878.Research output: Contribution to journal › Article › peer-review
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A new LC-MS/MS technique for separation of gangliosides using a phenyl-hexyl column: Systematic separation according to sialic acid class and ceramide subclass
Gobburi, A. L. P., Kipruto, E. W., Inman, D. M. & Anderson, D. J., 2021, In: Journal of Liquid Chromatography and Related Technologies. 44, 1-2, p. 114-125 12 p.Research output: Contribution to journal › Article › peer-review
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Metabolic vulnerability in the neurodegenerative disease glaucoma
Inman, D. M. & Harun-Or-Rashid, M., 30 Mar 2017, In: Frontiers in Neuroscience. 11, MAR, 146.Research output: Contribution to journal › Review article › peer-review