Projects per year
Personal profile
Research Interests
Neurodegeneration, Glaucoma, Metabolism, Mitochondria
URL
Area of Expertise
My laboratory investigates the mechanisms of glaucoma, with an emphasis on how neurons and glial cells interact during the process of degeneration. Our research has implicated metabolism in the pathogenesis of glaucoma, finding that transfer of energy substrate is compromised and mitochondria are dysfunctional prior to axon loss. These observations offer new targets for therapeutic development.
Education/Academic qualification
BS in Biology, Drexel University
PhD in Neuroscience, University of Virginia
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Optic nerve head (ONH) Chips f
Inman, D. (PI)
University of North Texas - Denton
30/09/22 → 31/05/25
Project: Research
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Mechanisms Underlying Endothel
Krishnamoorthy, R. (PI), Stankowska, D. (CoI), Inman, D. (CoI) & Clark, A. (CoI)
1/06/21 → 31/08/26
Project: Research
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Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model
Soto, I., Oglesby, E., Buckingham, B. P., Son, J. L., Roberson, E. D. O., Steele, M. R., Inman, D. M., Vetter, M. L., Horner, P. J. & Marsh-Armstrong, N., 9 Jan 2008, In: Journal of Neuroscience. 28, 2, p. 548-561 14 p.Research output: Contribution to journal › Article › peer-review
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Decreased energy capacity and increased autophagic activity in optic nerve axons with defective anterograde transport
Kleesattel, D., Crish, S. D. & Inman, D. M., 1 Dec 2015, In: Investigative Ophthalmology and Visual Science. 56, 13, p. 8215-8227 13 p.Research output: Contribution to journal › Article › peer-review
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Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucom
Dengler-Crish, C. M., Smith, M. A., Inman, D. M., Wilson, G. N., Young, J. W. & Crish, S. D., 2014, In: Frontiers in Neuroscience. 8, SEP, Article 290.Research output: Contribution to journal › Article › peer-review
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Physical size does not determine the unique histopathological response seen in the injured mouse spinal cord
Inman, D. M. & Steward, O., 1 Jan 2003, In: Journal of Neurotrauma. 20, 1, p. 33-42 10 p.Research output: Contribution to journal › Article › peer-review
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Metabolic vulnerability in the neurodegenerative disease glaucoma
Inman, D. M. & Harun-Or-Rashid, M., 30 Mar 2017, In: Frontiers in Neuroscience. 11, MAR, 146.Research output: Contribution to journal › Review article › peer-review