Projects per year
Personal profile
Research Interests
Neurodegeneration, Glaucoma, Metabolism, Mitochondria
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Area of Expertise
My laboratory investigates the mechanisms of glaucoma, with an emphasis on how neurons and glial cells interact during the process of degeneration. Our research has implicated metabolism in the pathogenesis of glaucoma, finding that transfer of energy substrate is compromised and mitochondria are dysfunctional prior to axon loss. These observations offer new targets for therapeutic development.
Education/Academic qualification
BS in Biology, Drexel University
PhD in Neuroscience, University of Virginia
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Collaborations and top research areas from the last five years
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Optic nerve head (ONH) Chips f
Inman, D. (PI)
University of North Texas - Denton
30/09/22 → 31/05/25
Project: Research
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Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma
Inman, D. M., Sappington, R. M., Horner, P. J. & Calkins, D. J., Mar 2006, In: Investigative Ophthalmology and Visual Science. 47, 3, p. 986-996 11 p.Research output: Contribution to journal › Article › peer-review
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Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve
Coughlin, L., Morrison, R. S., Horner, P. J. & Inman, D. M., 2015, In: Investigative Ophthalmology and Visual Science. 56, 3, p. 1437-1446 10 p.Research output: Contribution to journal › Article › peer-review
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Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma
Steele, M. R., Inman, D. M., Calkins, D. J., Horner, P. J. & Vetter, M. L., Mar 2006, In: Investigative Ophthalmology and Visual Science. 47, 3, p. 977-985 9 p.Research output: Contribution to journal › Article › peer-review
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Changes in ganglioside GM1 expression in glaucomic retina
Pappenhagen, N. & Inman, D. M., Oct 2018, In: Journal of Neuroscience Research. 96, 10, p. 1627-1630 4 p.Research output: Contribution to journal › Letter › peer-review
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The ketogenic diet and hypoxia promote mitophagy in the context of glaucoma
Morgan, A. B., Fan, Y. & Inman, D. M., 2024, In: Frontiers in Cellular Neuroscience. 18, 1409717.Research output: Contribution to journal › Article › peer-review