David Siderovski

Molecular cloning and expression analysis of rat Rgs12 and Rgs14

Snow, B. E., Antonio, L., Suggs, S., Gutstein, H. B. & Siderovski, D. P., 28 Apr 1997, In: Biochemical and Biophysical Research Communications. 233, 3, p. 770-777 8 p.

Research output: Contribution to journal › Article › peer-review

A Set of Human Putative Lymphocyte G₀/G₁ Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes

Siderovski, D. P., Blum, S., Forsdyke, R. E. & Forsdyke, D. R., Oct 1990, In: DNA and Cell Biology. 9, 8, p. 579-587 9 p.

Research output: Contribution to journal › Article › peer-review

Random mutagenesis of the human immunodeficiency virus type-1 frans-activator of transcription (HIV-1 Tat)

Siderovski, D. P., Matsuyama, T., Frigerio, E., Chui, S., Min, X., Erfle, H., Sumner-smith, M., Bamett, R. W. & Mak, T. W., 25 Oct 1992, In: Nucleic Acids Research. 20, 20, p. 5311-5320 10 p.

Research output: Contribution to journal › Article › peer-review

Structural determinants of rgs-rhogef signaling critical to entamoeba histolytica pathogenesis

Bosch, D. E., Kimple, A. J., Manning, A. J., Muller, R. E., Willard, F. S., MacHius, M., Rogers, S. L. & Siderovski, D. P., 8 Jan 2013, In: Structure. 21, 1, p. 65-75 11 p.

Research output: Contribution to journal › Article › peer-review

Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica

Bosch, D. E., Wittchen, E. S., Qiu, C., Burridge, K. & Siderovski, D. P., 11 Nov 2011, In: Journal of Biological Chemistry. 286, 45, p. 39236-39246 11 p.

Research output: Contribution to journal › Article › peer-review

The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face

Kimple, A. J., Willard, F. S., Giguère, P. M., Johnston, C. A., Mocanu, V. & Siderovski, D. P., Sep 2007, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 9, p. 1213-1220 8 p.

Research output: Contribution to journal › Article › peer-review

Two Gα_i1 rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activity

Zielinski, T., Kimple, A. J., Hutsell, S. Q., Koeff, M. D., Siderovski, D. P. & Lowery, R. G., Dec 2009, In: Journal of Biomolecular Screening. 14, 10, p. 1195-1206 12 p.

Research output: Contribution to journal › Article › peer-review

A direct fluorescence-based assay for RGS domain GTPase accelerating activity

Willard, F. S., Kimple, A. J., Johnston, C. A. & Siderovski, D. P., 15 May 2005, In: Analytical Biochemistry. 340, 2, p. 341-351 11 p.

Research output: Contribution to journal › Article › peer-review

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

Snyder, J. T., Rossman, K. L., Baumeister, M. A., Pruitt, W. M., Siderovski, D. P., Der, C. J., Lemmon, M. A. & Sondek, J., 7 Dec 2001, In: Journal of Biological Chemistry. 276, 49, p. 45868-45875 8 p.

Research output: Contribution to journal › Article › peer-review

GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling

Johnston, C. A., Taylor, J. P., Gao, Y., Kimple, A. J., Grigston, J. C., Chen, J. G., Siderovski, D. P., Jones, A. M. & Willard, F. S., 30 Oct 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 44, p. 17317-17322 6 p.

Research output: Contribution to journal › Article › peer-review

Structural determinants of affinity enhancement between GoLoco motifs and G-protein α subunit mutants

Bosch, D. E., Kimple, A. J., Sammond, D. W., Muller, R. E., Miley, M. J., Machius, M., Kuhlman, B., Willard, F. S. & Siderovski, D. P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3351-3358 8 p.

Research output: Contribution to journal › Article › peer-review

G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gβ and Gα _i protein subunits

Giguère, P. M., Laroche, G., Oestreich, E. A. & Siderovski, D. P., 10 Feb 2012, In: Journal of Biological Chemistry. 287, 7, p. 4863-4874 12 p.

Research output: Contribution to journal › Article › peer-review

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector

Willard, F. S., Willard, M. D., Kimple, A. J., Soundararajan, M., Oestreich, E. A., Li, X., Sowa, N. A., Kimple, R. J., Doyle, D. A., Der, C. J., Zylka, M. J., Snider, W. D. & Siderovski, D. P., 25 Mar 2009, In: PLoS ONE. 4, 3, e4884.

Research output: Contribution to journal › Article › peer-review

Fluorescence-based assays for RGS box function

Willard, F. S., Kimple, R. J., Kimple, A. J., Johnston, C. A. & Siderovski, D. P., 2004, In: Methods in Enzymology. 389, p. 56-71 16 p.

Research output: Contribution to journal › Article › peer-review

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

Colombo, K., Grill, S. W., Kimple, R. J., Willard, F. S., Siderovski, D. P. & Gönczy, P., 20 Jun 2003, In: Science. 300, 5627, p. 1957-1961 5 p.

Research output: Contribution to journal › Article › peer-review

Gγ-like (GGL) domains: New frontiers in G-protein signaling and β-propeller scaffolding

Sondek, J. & Siderovski, D. P., 1 Jun 2001, In: Biochemical Pharmacology. 61, 11, p. 1329-1337 9 p.

Research output: Contribution to journal › Article › peer-review

G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis

Giguère, P. M., Billard, M. J., Laroche, G., Buckley, B. K., Timoshchenko, R. G., McGinnis, M. W., Esserman, D., Foreman, O., Liu, P., Siderovski, D. P. & Tarrant, T. K., Jun 2013, In: Molecular Immunology. 54, 2, p. 193-198 6 p.

Research output: Contribution to journal › Article › peer-review

Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae

Chasse, S. A., Flanary, P., Parnell, S. C., Hao, N., Cha, J. Y., Siderovski, D. P. & Dohlman, H. G., Feb 2006, In: Eukaryotic Cell. 5, 2, p. 330-346 17 p.

Research output: Contribution to journal › Article › peer-review

Entamoeba histolytica rho1 regulates actin polymerization through a divergent, diaphanous-related formin

Bosch, D. E., Yang, B. & Siderovski, D. P., 6 Nov 2012, In: Biochemistry. 51, 44, p. 8791-8801 11 p.

Research output: Contribution to journal › Article › peer-review

Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica

Bosch, D. E., Kimple, A. J., Muller, R. E., Giguère, P. M., Machius, M., Willard, F. S., Temple, B. R. S. & Siderovski, D. P., Nov 2012, In: PLoS Pathogens. 8, 11, e1003040.

Research output: Contribution to journal › Article › peer-review

Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins

Willard, F. S., Low, A. B., McCudden, C. R. & Siderovski, D. P., Feb 2007, In: Cellular Signalling. 19, 2, p. 428-438 11 p.

Research output: Contribution to journal › Article › peer-review

Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia

Cohen, S. P., Buckley, B. K., Kosloffs, M., Garland, A. L., Bosch, D. E., Cheng, G., Radhakrishna, H., Brown, M. D., Willard, F. S., Arshavsky, V. Y., Tarran, R., Siderovski, D. P. & Kimple, A. J., 7 Dec 2012, In: Journal of Biological Chemistry. 287, 50, p. 41706-41719 14 p.

Research output: Contribution to journal › Article › peer-review

David Siderovski, PhD

Molecular cloning and expression analysis of rat Rgs12 and Rgs14

A Set of Human Putative Lymphocyte G₀/G₁ Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes

Random mutagenesis of the human immunodeficiency virus type-1 frans-activator of transcription (HIV-1 Tat)

Structural determinants of rgs-rhogef signaling critical to entamoeba histolytica pathogenesis

Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica

The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face

Two Gα_i1 rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activity

A direct fluorescence-based assay for RGS domain GTPase accelerating activity

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling

Structural determinants of affinity enhancement between GoLoco motifs and G-protein α subunit mutants

G-protein signaling modulator-3 regulates heterotrimeric G-protein dynamics through dual association with Gβ and Gα _i protein subunits

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector

Fluorescence-based assays for RGS box function

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

Gγ-like (GGL) domains: New frontiers in G-protein signaling and β-propeller scaffolding

G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis

Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae

Entamoeba histolytica rho1 regulates actin polymerization through a divergent, diaphanous-related formin

Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica

Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins

Regulator of G-protein signaling-21 (RGS21) is an inhibitor of bitter gustatory signaling found in lingual and airway epithelia

Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance

HIV-1 Tat Directly Interacts with the Interferon-Induced, Double-Stranded RNA-Dependent Kinase, PKR

A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation

David Siderovski, PhD

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