If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Area of Expertise

The brain is very sensitive to reductions in blood and oxygen supply. Major clinical events such as stroke, heart attack, and traumatic hemorrhage, and even the simple movement to the standing posture (orthostasis) can challenge this supply, often leading to damage to the brain tissue and subsequent neurological and physical impairment.
My laboratory strives to understand how the heart and brain respond to environmental and behavioral stressors in humans, with an emphasis on hemorrhage, orthostasis, exercise, and smoking (specifically electronic cigarettes). We also assess potential therapies that may improve how the heart and brain respond to reductions in blood and oxygen supply, including resistance breathing, oscillatory perfusion therapy, and occlusive exercise.

Education/Academic qualification

PhD in Physiology, RMIT University Melbourne

BAS in Physiology, RMIT University Melbourne

BS in Physiology, University of Melbourne

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 13 Similar Profiles
Lower Body Negative Pressure Medicine & Life Sciences
Hypovolemia Medicine & Life Sciences
Cerebrovascular Circulation Medicine & Life Sciences
Arterial Pressure Medicine & Life Sciences
Hemorrhage Medicine & Life Sciences
Stroke Volume Medicine & Life Sciences
Blood Pressure Medicine & Life Sciences
Blood Volume Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2019

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Oxidative stress
Young Adult
Oxidative Stress
Hemorrhage

Impact of environmental stressors on tolerance to hemorrhage in humans

Crandall, C. G., Rickards, C. A. & Johnson, B. D., 1 Feb 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 2, p. R88-R100

Research output: Contribution to journalReview articleResearchpeer-review

Lower Body Negative Pressure
Hemorrhage
Altitude Sickness
Hypovolemia
Military Personnel

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental Physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Ischemic Preconditioning
Exercise
Clinical Trials
Hypoxia-Inducible Factor 1
Microglia

Responses of cerebral blood velocity and tissue oxygenation to low-frequency oscillations during simulated haemorrhagic stress in humans

Anderson, G. K., Sprick, J. D., Park, F. S., Rosenberg, A. J. & Rickards, C. A., 1 Jan 2019, In : Experimental Physiology.

Research output: Contribution to journalArticleResearchpeer-review

Arterial Pressure
Middle Cerebral Artery
Hypovolemia
Frontal Lobe
Stroke Volume

Vive la résistance! The role of inspiratory resistance breathing on cerebral blood flow

Rickards, C. A., 1 Jul 2019, In : Respiratory Physiology and Neurobiology. 265, p. 76-82 7 p.

Research output: Contribution to journalReview articleResearchpeer-review

Cerebrovascular Circulation
Heart Arrest
Respiration
Hemorrhage
Intracranial Pressure