Projects per year
Personal profile
Area of Expertise
My research efforts within the North Texas Eye Research Institute (NTERI) are dedicated to the investigation and further development of the mouse as a useful model for the study of aqueous humor dynamics and primary open-angle glaucoma (POAG). Areas of expertise include studies (in living animals) of: aqueous humor dynamics, intraocular pressure measurement, generation and development of transgenic models of POAG using viral vectors, visualization of the eye using spectral domain ocular coherence tomography (SD-OCT), and electroretinography. Projects currently under way include an investigation, using 5XFAD mice (which express five familial Alzheimer’s Disease (AD) mutations) into a possible connection between AD and POAG I also routinely interact with other NTERI members in a multi-disciplinary manner.
Education/Academic qualification
BS in Applied Biology, Glasgow Caledonian University
BS in Applied & Clinical Biochemistry, Glasgow Caledonian University
PhD in Pharmacology, University of Glasgow
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Projects
- 12 Finished
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Targeting FMNL2/Rho-GTPase Pat
Clark, A. (CoI), Millar, C. (PI), Millar, C. (CoI) & Ellis, D. (CoI)
1/01/24 → 31/12/25
Project: Research
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Novel Hybrid Molecule with Bot
Millar, C. (CoI) & Acharya, S. (PI)
1/03/20 → 31/08/26
Project: Research
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Anterior chamber perfusion versus posterior chamber perfusion does not influence measurement of aqueous outflow facility in living mice by constant flow infusion
Lopez, N. N., Patel, G. C., Raychaudhuri, U., Aryal, S., Phan, T. N., Clark, A. F. & Millar, J. C., Nov 2017, In: Experimental eye research. 164, p. 95-108 14 p.Research output: Contribution to journal › Article › peer-review
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Atriopeptin lowers aqueous humor formation and intraocular pressure and elevates ciliary cyclic GMP but lacks uveal vascular effects in the bovine perfused eye
Millar, J. C., Shahidullah, M. & Wilson, W. S., Feb 1997, In: Journal of Ocular Pharmacology and Therapeutics. 13, 1, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
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Serotonergic and endothelin (ET)-1 effects on aqueous humor dynamics in monkeys
Millar, C., Kiland, J., Peterson, J., Hubbard, W. C., Osborne, N. M. & Kaufman, P. L., 15 Feb 1996, In: Investigative Ophthalmology and Visual Science. 37, 3, p. S836Research output: Contribution to journal › Article › peer-review
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Impaired axonal transport contributes to neurodegeneration in a Cre-inducible mouse model of myocilin-associated glaucoma
Kaipa, B. R., Kasetti, R., Sundaresan, Y., Li, L., Yacoub, S., Millar, J. C., Cho, W., Skowronska-Krawczyk, D., Maddineni, P., Palczewski, K. & Zode, G. S., 10 Mar 2025, In: JCI Insight. 10, 5, e188710.Research output: Contribution to journal › Article › peer-review
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Toward an Improved Understanding of the Physiology of Aqueous Humor Flow
Cameron Millar, J., Jan 2014, In: Investigative Ophthalmology and Visual Science. 55, 1, p. 404 1 p.Research output: Contribution to journal › Comment/debate