Projects per year
Personal profile
Area of Expertise
My research efforts within the North Texas Eye Research Institute (NTERI) are dedicated to the investigation and further development of the mouse as a useful model for the study of aqueous humor dynamics and primary open-angle glaucoma (POAG). Areas of expertise include studies (in living animals) of: aqueous humor dynamics, intraocular pressure measurement, generation and development of transgenic models of POAG using viral vectors, visualization of the eye using spectral domain ocular coherence tomography (SD-OCT), and electroretinography. Projects currently under way include an investigation, using 5XFAD mice (which express five familial Alzheimer’s Disease (AD) mutations) into a possible connection between AD and POAG I also routinely interact with other NTERI members in a multi-disciplinary manner.
Education/Academic qualification
BS in Applied Biology, Glasgow Caledonian University
BS in Applied & Clinical Biochemistry, Glasgow Caledonian University
PhD in Pharmacology, University of Glasgow
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Collaborations and top research areas from the last five years
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Glucocorticoids, Ocular Hypertension and Glaucoma
Clark, A. (PI) & Millar, C. (CoI)
30/09/20 → 31/08/25
Project: Research
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Novel Hybrid Molecule with Both IOP Lowering and Neuroprotective Effects for Treatment of Glaucoma
Ellis, D. (PI) & Millar, C. (CoI)
1/03/20 → 31/08/25
Project: Research
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Novel Hybrid Molecule with Both IOP Lowering and Neuroprotective Effects for Treatment of Glaucoma
Millar, C. (PI)
1/03/20 → 31/08/25
Project: Research
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Glucocorticoids, Ocular Hypertension, and Glaucoma
Clark, A. (PI) & Millar, C. (CoI)
30/09/18 → 31/08/19
Project: Research
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Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure
Wang, W. H., McNatt, L. G., Pang, I. H., Millar, J. C., Hellberg, P. E., Hellberg, M. H., Steely, H. T., Rubin, J. S., Fingert, J. H., Sheffield, V. C., Stone, E. M. & Clark, A. F., Mar 2008, In: Journal of Clinical Investigation. 118, 3, p. 1056-1064 9 p.Research output: Contribution to journal › Article › peer-review
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BMP and activin membrane bound inhibitor regulates the extracellular matrix in the trabecular meshwork
Hernandez, H., Cameron Millar, J., Curry, S. M., Clark, A. F. & McDowell, C. M., Apr 2018, In: Investigative Ophthalmology and Visual Science. 59, 5, p. 2154-2166 13 p.Research output: Contribution to journal › Article › peer-review
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Effect of cromakalim prodrug 1 (CKLP1) on aqueous humor dynamics and feasibility of combination therapy with existing ocular hypotensive agents
Chowdhury, U. R., Rinkoski, T. A., Bahler, C. K., Millar, J. C., Bertrand, J. A., Holman, B. H., Sherwood, J. M., Overby, D. R., Stoltz, K. L., Dosa, P. I. & Fautsch, M. P., Nov 2017, In: Investigative Ophthalmology and Visual Science. 58, 13, p. 5731-5742 12 p.Research output: Contribution to journal › Article › peer-review
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Effect of immunomodulation with anti-CD40L antibody on adenoviral-mediated transgene expression in mouse anterior segment
Cameron Millar, J., Pang, I. H., Wang, W. H., Wang, Y. & Clark, A. F., 9 Jan 2008, In: Molecular vision. 14, p. 10-19 10 p.Research output: Contribution to journal › Article › peer-review
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Noninvasive measurement of rodent intraocular pressure with a rebound tonometer
Wang, W. H., Millar, J. C., Pang, I. H., Wax, M. B. & Clark, A. F., Dec 2005, In: Investigative Ophthalmology and Visual Science. 46, 12, p. 4617-4621 5 p.Research output: Contribution to journal › Article › peer-review