Projects per year
Personal profile
Area of Expertise
My research efforts within the North Texas Eye Research Institute (NTERI) are dedicated to the investigation and further development of the mouse as a useful model for the study of aqueous humor dynamics and primary open-angle glaucoma (POAG). Areas of expertise include studies (in living animals) of: aqueous humor dynamics, intraocular pressure measurement, generation and development of transgenic models of POAG using viral vectors, visualization of the eye using spectral domain ocular coherence tomography (SD-OCT), and electroretinography. Projects currently under way include an investigation, using 5XFAD mice (which express five familial Alzheimer’s Disease (AD) mutations) into a possible connection between AD and POAG I also routinely interact with other NTERI members in a multi-disciplinary manner.
Education/Academic qualification
BS in Applied Biology, Glasgow Caledonian University
BS in Applied & Clinical Biochemistry, Glasgow Caledonian University
PhD in Pharmacology, University of Glasgow
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Projects
- 7 Finished
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Dose-Dependence Study of Dronabinol on Mouse Intraocular Pressure
Pang, I. & Millar, C.
25/09/17 → 31/12/17
Project: Research
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Effect of Repeated Doses of Rhodes Formulations on Mouse Intraocular Pressure
Pang, I., Millar, C. & Liu, Y.
7/06/17 → 31/12/17
Project: Research
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Preclinical Evaluation of Graybug Vision Compound
Clark, A., Tovar-Vidales, T., Liu, Y. & Millar, C.
5/06/17 → 4/06/19
Project: Research
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Effect of Shire Compound on Mouse Intraocular Pressure and Aqueous Humor Hydrodynamics
Pang, I., Millar, C. & Liu, Y.
1/10/16 → 30/09/19
Project: Research
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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms
McDowell, C. M., Kizhatil, K., Elliott, M. H., Overby, D. R., van Batenburg-Sherwood, J., Cameron Millar, J., Kuehn, M. H., Zode, G., Acott, T. S., Anderson, M. G., Bhattacharya, S. K., Bertrand, J. A., Borras, T., Bovenkamp, D. E., Cheng, L., Danias, J., De Ieso, M. L., Du, Y., Faralli, J. A., Fuchshofer, R., & 60 others, Feb 2022, In: Investigative Ophthalmology and Visual Science. 63, 2, 12.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Early-Onset Glaucoma in egl1 Mice Homozygous for Pitx2 Mutation
Kodati, B., Merchant, S. A., Cameron Millar, J. & Liu, Y., Mar 2022, In: Biomedicines. 10, 3, 516.Research output: Contribution to journal › Article › peer-review
Open Access -
ID1 and ID3 are negative regulators of TGFβ2-induced ocular hypertension and compromised aqueous humor outflow facility in mice
Mody, A. A., Cameron Millar, J. & Clark, A. F., 2021, In: Investigative Ophthalmology and Visual Science. 62, 6, A2.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
Patel, P. D., Chen, Y. L., Kasetti, R. B., Maddineni, P., Mayhew, W., Millar, J. C., Ellis, D. Z., Sonkusare, S. K. & Zode, G. S., 20 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 16, e2022461118.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension
Wong, V. H. Y., Zhao, D., Bui, B. V., Millar, C. J. & Nguyen, C. T. O., Jan 2021, In: Experimental eye research. 202, 108348.Research output: Contribution to journal › Article › peer-review
2 Scopus citations