Bruce Bunnell

A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways

Matossian, M. D., Burks, H. E., Elliott, S., Hoang, V. T., Zuercher, W. J., Wells, C., Drewry, D. H., Kapadia, N., Chang, T., Yan, T., Windsor, G. O., Nguyen, K., Fang, F., Nephew, K. P., Buechlein, A., Rusch, D. B., Sabol, R. A., Ucar, D. A., Zabaleta, J. & Miele, L. & 3 others, Bunnell, B. A., Collins-Burow, B. M. & Burow, M. E., 1 Sep 2020, In: Anti-Cancer Drugs. 31, 8, p. 759-775 17 p.

Research output: Contribution to journal › Article › peer-review

Age of the donor reduces the ability of human adipose-derived stem cells to alleviate symptoms in the experimental autoimmune encephalomyelitis mouse model

Scruggs, B. A., Semon, J. A., Zhang, X., Zhang, S., Bowles, A. C., Pandey, A. C., Imhof, K. M. P., Kalueff, A. V., Gimble, J. M. & Bunnell, B. A., Oct 2013, In: Stem Cells Translational Medicine. 2, 10, p. 797-807 11 p.

Research output: Contribution to journal › Article › peer-review

Concise review: Adipose-derived stromal vascular fraction cells and stem cells: Let's not get lost in translation

Gimble, J. M., Bunnell, B. A., Chiu, E. S. & Guilak, F., May 2011, In: Stem Cells. 29, 5, p. 749-754 6 p.

Research output: Contribution to journal › Article › peer-review

Innate immune activation in the pathogenesis of a murine model of globoid cell leukodystrophy

Snook, E. R., Fisher-Perkins, J. M., Sansing, H. A., Lee, K. M., Alvarez, X., MacLean, A. G., Peterson, K. E., Lackner, A. A. & Bunnell, B. A., Feb 2014, In: American Journal of Pathology. 184, 2, p. 382-396 15 p.

Research output: Contribution to journal › Article › peer-review

Obesity enhances the conversion of adipose-derived stromal/stem cells into carcinoma-associated fibroblast leading to cancer cell proliferation and progression to an invasive phenotype

Strong, A. L., Pei, D. T., Hurst, C. G., Gimble, J. M., Burow, M. E. & Bunnell, B. A., 2017, In: Stem Cells International. 2017, 9216502.

Research output: Contribution to journal › Article › peer-review

Enhanced Angiogenesis in HUVECs Preconditioned with Media from Adipocytes Differentiated from Lipedema Adipose Stem Cells In Vitro

Al-Ghadban, S., Walczak, S. G., Isern, S. U., Martin, E. C., Herbst, K. L. & Bunnell, B. A., Sep 2023, In: International journal of molecular sciences. 24, 17, 13572.

Research output: Contribution to journal › Article › peer-review

Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis

Wang, G., Bunnell, B. A., Painter, R. G., Quiniones, B. C., Tom, S., Lanson, N. A., Spees, J. L., Bertucci, D., Peister, A., Weiss, D. J., Valentine, V. G., Prockop, D. J. & Kolls, J. K., 4 Jan 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 1, p. 186-191 6 p.

Research output: Contribution to journal › Article › peer-review

Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells

Vanderbyl, S. L., Sullenbarger, B., White, N., Perez, C. F., MacDonald, G. N., Stodola, T., Bunnell, B. A., Ledebur, H. C. & Lasky, L. C., Dec 2005, In: Experimental Hematology. 33, 12, p. 1470-1476 7 p.

Research output: Contribution to journal › Article › peer-review

Survival of aging CD264⁺ and CD264⁻ populations of human bone marrow mesenchymal stem cells is independent of colony-forming efficiency

Madsen, S. D., Jones, S. H., Tucker, H. A., Giler, M. K., Muller, D. C., Discher, C. T., Russell, K. C., Dobek, G. L., Sammarco, M. C., Bunnell, B. A. & O'Connor, K. C., 1 Jan 2020, In: Biotechnology and Bioengineering. 117, 1, p. 223-237 15 p.

Research output: Contribution to journal › Article › peer-review

Gender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction

Frazier, T., Lee, S., Bowles, A., Semon, J., Bunnell, B., Wu, X. & Gimble, J., 3 Jul 2018, In: Adipocyte. 7, 3, p. 183-189 7 p.

Research output: Contribution to journal › Article › peer-review

Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction

Baber, S. R., Deng, W., Master, R. G., Bunnell, B. A., Taylor, B. K., Murthy, S. N., Hyman, A. L. & Kadowitz, P. J., Feb 2007, In: American Journal of Physiology - Heart and Circulatory Physiology. 292, 2, p. H1120-H1128

Research output: Contribution to journal › Article › peer-review

Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2

Bashore, F. M., Min, S. M., Chen, X., Howell, S., Rinderle, C. H., Morel, G., Silvaroli, J. A., Wells, C. I., Bunnell, B. A., Drewry, D. H., Pabla, N. S., Ultanir, S. K., Bullock, A. N. & Axtman, A. D., 8 Aug 2024, In: ACS Medicinal Chemistry Letters. 15, 8, p. 1325-1333 9 p.

Research output: Contribution to journal › Article › peer-review

Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer

King, C. T., Matossian, M. D., Savoie, J. J., Nguyen, K., Wright, M. K., Byrne, C. E., Elliott, S., Burks, H. E., Bratton, M. R., Pashos, N. C., Bunnell, B. A., Burow, M. E., Collins-Burow, B. M. & Martin, E. C., 8 Jun 2022, In: Frontiers in Molecular Biosciences. 9, 847505.

Research output: Contribution to journal › Article › peer-review

Comparative proteomic analyses of human adipose extracellular matrices decellularized using alternative procedures

Thomas-Porch, C., Li, J., Zanata, F., Martin, E. C., Pashos, N., Genemaras, K., Poche, J. N., Totaro, N. P., Bratton, M. R., Gaupp, D., Frazier, T., Wu, X., Ferreira, L. M., Tian, W., Wang, G., Bunnell, B. A., Flynn, L., Hayes, D. & Gimble, J. M., Sep 2018, In: Journal of Biomedical Materials Research - Part A. 106, 9, p. 2481-2493 13 p.

Research output: Contribution to journal › Article › peer-review

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy

Meneghini, V., Lattanzi, A., Tiradani, L., Bravo, G., Morena, F., Sanvito, F., Calabria, A., Bringas, J., Fisher-Perkins, J. M., Dufour, J. P., Baker, K. C., Doglioni, C., Montini, E., Bunnell, B. A., Bankiewicz, K., Martino, S., Naldini, L. & Gritti, A., 1 May 2016, In: EMBO Molecular Medicine. 8, 5, p. 489-510 22 p.

Research output: Contribution to journal › Article › peer-review

In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types

Matossian, M. D., Chang, T., Wright, M. K., Burks, H. E., Elliott, S., Sabol, R. A., Wathieu, H., Windsor, G. O., Alzoubi, M. S., King, C. T., Bursavich, J. B., Ham, A. M., Savoie, J. J., Nguyen, K., Baddoo, M., Flemington, E., Sirenko, O., Cromwell, E. F., Hebert, K. L. & Lau, F. & 13 others, Izadpanah, R., Brown, H., Sinha, S., Zabaleta, J., Riker, A. I., Moroz, K., Miele, L., Zea, A. H., Ochoa, A., Bunnell, B. A., Collins-Burow, B. M., Martin, E. C. & Burow, M. E., Jan 2022, In: Clinical and Translational Oncology. 24, 1, p. 127-144 18 p.

Research output: Contribution to journal › Article › peer-review

Increase in Leptin and PPAR-γ Gene Expression in Lipedema Adipocytes Differentiated in vitro from Adipose-Derived Stem Cells

Al-Ghadban, S., Diaz, Z. T., Singer, H. J., Mert, K. B. & Bunnell, B. A., 12 Feb 2020, In: Cells. 9, 2, 267.

Research output: Contribution to journal › Article › peer-review

Obesity modulates the gut microbiome in triple-negative breast cancer

Hossain, F., Majumder, S., David, J., Bunnell, B. A. & Miele, L., Oct 2021, In: Nutrients. 13, 10, 3656.

Research output: Contribution to journal › Article › peer-review

Characterization of a murine pressure ulcer model to assess efficacy of adipose-derived stromal cells

Strong, A. L., Bowles, A. C., MacCrimmon, C. P., Lee, S. J., Frazier, T. P., Katz, A. J., Gawronska-Kozak, B., Bunnell, B. A. & Gimble, J. M., 2015, In: Plastic and Reconstructive Surgery - Global Open. 3, 3, e334.

Research output: Contribution to journal › Article › peer-review

Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells

Gimble, J. M., Guilak, F. & Bunnell, B. A., 2010, In: Stem Cell Research and Therapy. 1, 2, 19.

Research output: Contribution to journal › Article › peer-review

Human Mesenchymal Stem Cell-Derived Miniature Joint System for Disease Modeling and Drug Testing

Li, Z., Lin, Z., Liu, S., Yagi, H., Zhang, X., Yocum, L., Romero-Lopez, M., Rhee, C., Makarcyzk, M. J., Yu, I., Li, E. N., Fritch, M. R., Gao, Q., Goh, K. B., O'Donnell, B., Hao, T., Alexander, P. G., Mahadik, B., Fisher, J. P. & Goodman, S. B. & 3 others, Bunnell, B. A., Tuan, R. S. & Lin, H., 25 Jul 2022, In: Advanced Science. 9, 21, 2105909.

Research output: Contribution to journal › Article › peer-review

Aberrant Expression of COX-2 and FOXG1 in Infrapatellar Fat Pad-Derived ASCs from Pre-Diabetic Donors

O’Donnell, B. T., Monjure, T. A., Al-Ghadban, S., Ives, C. J., L’Ecuyer, M. P., Rhee, C., Romero-Lopez, M., Li, Z., Goodman, S. B., Lin, H., Tuan, R. S. & Bunnell, B. A., Aug 2022, In: Cells. 11, 15, 2367.

Research output: Contribution to journal › Article › peer-review

Macrophage phenotypes modulate neoangiogenesis and fibroblast profiles in synovial-like organoid cultures

Gao, Q., Zhang, X., Makarcyzk, M. J., Wong, L. E., Quig, M. S. V., Shinohara, I., Murayama, M., Chow, S. K. H., Bunnell, B. A., Lin, H. & Goodman, S. B., 2025, (Accepted/In press) In: Osteoarthritis and Cartilage.

Research output: Contribution to journal › Article › peer-review

Novel lipid mediator 7S,14R-docosahexaenoic acid: biogenesis and harnessing mesenchymal stem cells to ameliorate diabetic mellitus and retinal pericyte loss

Lu, Y., Tian, H., Peng, H., Wang, Q., Bunnell, B. A., Bazan, N. G. & Hong, S., 2024, In: Frontiers in Cell and Developmental Biology. 12, 1380059.

Research output: Contribution to journal › Article › peer-review

Doublecortin may play a role in defining chondrocyte phenotype

Ge, D., Zhang, Q. S., Zabaleta, J., Zhang, Q., Liu, S., Reiser, B., Bunnell, B. A., Braun, S. E., O'Brien, M. J., Savoie, F. H. & You, Z., 22 Apr 2014, In: International journal of molecular sciences. 15, 4, p. 6941-6960 20 p.

Research output: Contribution to journal › Article › peer-review

Bruce Bunnell, PhD

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