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Personal profile

Area of Expertise

Forensic genetics traditionally has been dedicated to analysis of human DNA markers for identity purposes to support criminal and civil investigations. However, with the demands of stakeholders and advances in technologies and bioinformatics, there is a substantial expansion of the applications of forensic genetics (or, better yet, forensic genomics). In addition to identification of humans associated with crime, or missing persons due to mass disasters or other crimes, other areas of application include molecular autopsy and microbial forensics.
Our research group has an advanced forensic genomics program using cutting edge genomics and technologies to effectively bolster current forensic and biosecurity capabilities. Some areas of interest are: computational genomics and bioinformatics; mixture interpretation; development of genetic diagnostics and detection capabilities; identification of novel genetic markers for human identification; population genetics studies; human microbiome studies for identification purposes; molecular autopsy (i.e. pharmacogenetics); and molecular mechanisms for DNA repair. These research efforts support the government in achieving its missions of law enforcement, combatting terrorism, providing biosafety, and preserving national biosecurity, all for a healthier and safer society.

Education/Academic qualification

PhD in Genetics, Virginia Tech

Fingerprint Dive into the research topics where Bruce Budowle is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Projects 2009 2020

Research Output 1981 2019

A genome-wide association study of tramadol metabolism from post-mortem samples

Wendt, F. R., Rahikainen, A. L., King, J. L., Sajantila, A. & Budowle, B., 1 Jan 2019, In : Pharmacogenomics Journal.

Research output: Contribution to journalArticleResearchpeer-review

Tramadol
Genome-Wide Association Study
Polypharmacy
Phenotype
Peptides

A pathway-driven predictive model of tramadol pharmacogenetics

Wendt, F. R., Novroski, N. M. M., Rahikainen, A. L., Sajantila, A. & Budowle, B., 1 Jul 2019, In : European Journal of Human Genetics. 27, 7, p. 1143-1156 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Tramadol
Pharmacogenetics
Peptides
Phenotype
Genes

Assessment of impact of DNA extraction methods on analysis of human remain samples on massively parallel sequencing success

Zeng, X., Elwick, K., Mayes, C., Takahashi, M., King, J. L., Gangitano, D., Budowle, B. & Hughes-Stamm, S., 14 Jan 2019, In : International journal of legal medicine. 133, 1, p. 51-58 8 p.

Research output: Contribution to journalArticleResearchpeer-review

High-Throughput Nucleotide Sequencing
DNA
Bone and Bones
Hair
Single Nucleotide Polymorphism

Compound stutter in D2S1338 and D12S391

Woerner, A. E., King, J. L. & Budowle, B., 1 Mar 2019, In : Forensic Science International: Genetics. 39, p. 50-56 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Linear Models
Nucleotides
High-Throughput Nucleotide Sequencing

Copan microFLOQ® Direct Swab collection of bloodstains, saliva, and semen on cotton cloth

Sherier, A. J., Kieser, R. E., Novroski, N. M. M., Wendt, F. R., King, J. L., Woerner, A. E., Ambers, A., Garofano, P. & Budowle, B., 1 Jan 2019, In : International journal of legal medicine.

Research output: Contribution to journalArticleResearchpeer-review

Semen
Saliva
Coloring Agents
Polymerase Chain Reaction
Blood Stains