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Personal profile

Area of Expertise

My goal is to better understand how the brain controls blood pressure, both under normal conditions and in the presence of disorders that raise blood pressure. Currently, my laboratory focuses on two conditions that lead to high blood pressure: obesity and sleep apnea. Both of these conditions change how the brain controls blood pressure, but the mechanisms are not well understood. Although, ideally, obesity and sleep apnea can be managed, many find it difficult to control body weight in the long term and not may tolerate current treatments for sleep apnea. As these conditions continue to become more prevalent, the cardiovascular disease that accompanies them also becomes a major health issue nationwide. The current treatments for high blood pressure are numerous, and many medications act within the brain to control blood pressure.
Our work examines which treatments are ideal for management of cardiovascular disease with these conditions by determining how the brain changes with obesity and sleep apnea and whether current medications can reverse these changes. Because high blood pressure has many causes, treatments should be individually optimized to best manage control of blood pressure in the context of the conditions that accompany it.

Education/Academic qualification

PhD in Neuroscience, University of Pittsburgh

BS in Psychology, Emory University

Fingerprint Dive into the research topics where Ann Schreihofer is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Research Output 1992 2018

  • 2336 Citations
  • 29 h-Index
  • 49 Article
  • 2 Chapter
Zucker Rats
Solitary Nucleus
Baroreflex
Homeostasis
Glucose
4 Citations (Scopus)
Zucker Rats
Reflex
Arterial Pressure
Baroreflex
Sciatic Nerve
8 Citations (Scopus)

Development of attenuated baroreflexes in obese Zucker rats coincides with impaired activation of nucleus tractus solitarius

Guimaraes, P. S., Huber, D. A., Campagnole-Santos, M. J. & Schreihofer, A. M., 1 May 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 306, 9

Research output: Contribution to journalArticleResearchpeer-review

Zucker Rats
Solitary Nucleus
Baroreflex
Arterial Pressure
Hydralazine
14 Citations (Scopus)

Increasing angiotensin-(1-7) levels in the brain attenuates metabolic syndrome-related risks in fructose-fed rats

Guimaraes, P. S., Oliveira, M. F., Braga, J. F., Nadu, A. P., Schreihofer, A. M., Santos, R. A. S. & Campagnole-Santos, M. J., 1 Jan 2014, In : Hypertension. 63, 5, p. 1078-1085 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolic Brain Diseases
Fructose
Intraventricular Infusions
Intra-Abdominal Fat
Baroreflex

Insights into a successful dual scientific career and partnership.

Schreihofer, A. M. & Schreihofer, D., 1 Jun 2012, In : The Physiologist. 55, 3, p. 94-95 2 p.

Research output: Contribution to journalArticleResearchpeer-review

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