• 2415 Citations
  • 27 h-Index
1967 …2019

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Article
2019

[ 99 mTc-HYNIC-N-dodecylamide]:a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging

Isaac-Olivé, K., Ocampo-García, B. E., Aranda-Lara, L., Santos-Cuevas, C. L., Jiménez-Mancilla, N. P., Luna-Gutiérrez, M. A., Medina, L. A., Nagarajan, B., Sabnis, N., Raut, S., Prokai, L. & Lacko, A. G., 14 Jan 2019, In : Nanoscale. 11, 2, p. 541-551 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S., Sabnis, N., Kong, X., Yang, X., Lopez-Berestein, G., Lacko, A. G. & Sood, A. K., 15 Aug 2019, In : Oncogene. 38, 33, p. 6095-6108 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

The SR-B1 Receptor as a Potential Target for Treating Glioblastoma

Berney, E., Sabnis, N., Panchoo, M., Raut, S., Dickerman, R. & Lacko, A. G., 1 Jan 2019, In : Journal of Oncology. 2019, 1805841.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Scavenger receptor class B type 1 regulates neuroblastoma cell proliferation, migration and invasion

Panchoo, M. & Lacko, A., 1 Jan 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 614-620 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Fluorescence properties of doxorubicin in PBS buffer and PVA films

Shah, S., Chandra, A., Kaur, A., Sabnis, N., Lacko, A., Gryczynski, Z., Fudala, R. & Gryczynski, I., 1 May 2017, In : Journal of Photochemistry and Photobiology B: Biology. 170, p. 65-69 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

SR-B1-targeted nanodelivery of anti-cancer agents: A promising new approach to treat triplenegative breast cancer

Johnson, R., Sabnis, N., Sun, X., Ahluwalia, R. & Lacko, A. G., 2 Jun 2017, In : Breast Cancer: Targets and Therapy. 9, p. 383-392 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Superparamagnetic reconstituted high-density lipoprotein nanocarriers for magnetically guided drug delivery

Sabnis, S., Sabnis, N. A., Raut, S. & Lacko, A. G., 22 Feb 2017, In : International Journal of Nanomedicine. 12, p. 1453-1464 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Ultrasound-stimulated drug delivery using therapeutic reconstituted high-density lipoprotein nanoparticles

Xiong, F., Nirupama, S., Sirsi, S. R., Lacko, A. & Hoyt, K., 1 Jan 2017, In : Nanotheranostics. 1, 4, p. 440-449 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2016

Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent

Shah, S., Chib, R., Raut, S., Bermudez, J., Sabnis, N., Duggal, D., Kimball, J. D., Lacko, A. G., Gryczynski, Z. & Gryczynski, I., Feb 2016, In : Journal of Photochemistry and Photobiology B: Biology. 155, p. 60-65 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2015

HDL as a drug and nucleic acid delivery vehicle

Lacko, A. G., Sabnis, N. A., Nagarajan, B. & McConathy, W. J., 1 Jan 2015, In : Frontiers in Pharmacology. 6, OCT, 1 p.

Research output: Contribution to journalArticle

31 Scopus citations
2014

A homodimeric BODIPY rotor as a fluorescent viscosity sensor for membrane-mimicking and cellular environments

Raut, S., Kimball, J., Fudala, R., Doan, H., Maliwal, B., Sabnis, N., Lacko, A., Gryczynski, I., Dzyuba, S. V. & Gryczynski, Z., 19 Nov 2014, In : Physical Chemistry Chemical Physics. 16, 48, p. 27037-27042 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
2013

Pre-clinical evaluation of rHDL encapsulated retinoids for the treatment of neuroblastoma

Sabnis, N., Pratap, S., Akopova, I., Bowman, P. W. & Lacko, A. G., 1 Mar 2013, In : Frontiers in Pediatrics. 1, MAR, 6.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations
2012

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

Sabnis, N., Nair, M., Israel, M., McConathy, W. J. & Lacko, A. G., 5 Dec 2012, In : International Journal of Nanomedicine. 7, p. 975-983 9 p.

Research output: Contribution to journalArticle

38 Scopus citations
2011

Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

Shahzad, M. M. K., Mangala, L. S., Han, H. D., Lu, C., Bottsford-Miller, J., Nishimura, M., Mora, E. M., Lee, J. W., Stone, R. L., Pecot, C. V., Thanapprapasr, D., Roh, J. W., Gaur, P., Nair, M. P., Park, Y. Y., Sabnis, N., Deavers, M. T., Lee, J. S., Ellis, L. M., Lopez-Berestei, G. & 4 others, McConathy, W. J., Prokai, L., Lacko, A. G. & Sood, A. K., Apr 2011, In : Neoplasia. 13, 4, p. 309-319 11 p.

Research output: Contribution to journalArticle

144 Scopus citations

Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF)

McConathy, W. J., Paranjape, S., Mooberry, L., Buttreddy, S., Nair, M. & Lacko, A. G., 1 Apr 2011, In : Drug Delivery and Translational Research. 1, 2, p. 113-120 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2010

Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier

Mooberry, L. K., Nair, M., Paranjape, S., McConathy, W. J. & Lacko, A. G., 1 Jan 2010, In : Journal of Drug Targeting. 18, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Studies on solvatochromic properties of aminophenylstyryl-quinolinum dye, LDS 798, and its application in studying submicron lipid based structure

Sarkar, P., Luchowski, R., Raut, S. L., Sabnis, N., Remaley, A., Lacko, A. G., Thamake, S., Gryczynski, Z. & Gryczynski, I., 1 Dec 2010, In : Biophysical Chemistry. 153, 1, p. 61-69 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008
10 Scopus citations

Evaluation of synthetic/reconstituted high-density lipoproteins as delivery vehicles for paclitaxel

McConathy, W. J., Nair, M. P., Paranjape, S., Mooberry, L. & Lacko, A. G., 1 Feb 2008, In : Anti-Cancer Drugs. 19, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

99 Scopus citations
2007

Doxorubicin transport by RALBP1 and ABCG2 in lung and breast cancer

Singhal, S. S., Singhal, J., Nair, M. P., Lacko, A. G., Awasthi, Y. C. & Awasthi, S., 1 Mar 2007, In : International journal of oncology. 30, 3, p. 717-725 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
2006

Structural differences between wild-type and fish eye disease mutant of lecithin:cholesterol acyltransferase

Reshetnyak, Y., Tchedre, K. T., Nair, M. P., Pritchard, P. H. & Lacko, A. G., Aug 2006, In : Journal of Biomolecular Structure and Dynamics. 24, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model

Lacko, A. G., Nair, M. P., Paranjape, S., Mooberry, L. & McConathy, W. J., 1 Jun 2006, In : Chemotherapy. 52, 4, p. 171-173 3 p.

Research output: Contribution to journalArticle

26 Scopus citations
2004

Cardiovascular risk factors in Mexican-American children at risk for type 2 diabetes mellitus (T2DM)

Urrutia-Rojas, X., Menchaca, J., Wadley, W., Ahmad, N., Lacko, A., Bae, S., Spellman, C., Kudchodkar, B., Kudolo, G. & McConathy, W., 1 Apr 2004, In : Journal of Adolescent Health. 34, 4, p. 290-299 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Characterization of lecithin:cholesterol acyltransferase expressed in a human lung cell line

Lane, S. B., Tchedre, K. T., Nair, M. P., Thigpen, A. E. & Lacko, A. G., 1 Aug 2004, In : Protein Expression and Purification. 36, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2002

High density lipoprotein complexes as delivery vehicles for anticancer drugs

Lacko, A. G., Nair, M. P., Paranjape, S., Johnson, S. & McConathy, W. J., 19 Aug 2002, In : Anticancer Research. 22, 4, p. 2045-2049 5 p.

Research output: Contribution to journalArticle

83 Scopus citations
2001

High cholesterol diet down regulates the activity of activator protein-1 but not nuclear factor-kappa B in rabbit brain

Kálmán, J., Kudchodkar, B. J., Krishnamoorthy, R., Dory, L., Lacko, A. G. & Agarwal, N., 16 Feb 2001, In : Life Sciences. 68, 13, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Probing the 121-136 domain of lecithin:cholesterol acyltransferase using antibodies

Murray, K. R., Nair, M. P., Ayyobi, A. F., Hill, J. S., Pritchard, P. H. & Lacko, A. G., 15 Jan 2001, In : Archives of Biochemistry and Biophysics. 385, 2, p. 267-275 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2000

Apolipoprotein D in the aging brain and in Alzheimer's dementia

Kalman, J., McConathy, W., Araoz, C., Kasa, P. & Lacko, A. G., 1 Jan 2000, In : Neurological Research. 22, 4, p. 330-336 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Biochemical and compositional analyses of recombinant lecithin:cholesterol acyltransferase (LCAT) obtained from a hepatic source

Ayyobi, A. F., Lacko, A. G., Murray, K., Nair, M. P., Li, M., Molhuizen, H. O. F. & Pritchard, P. H., 24 Feb 2000, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1484, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Dietary fat modulates serum paraoxonase 1 activity in rats

Kudchodkar, B. J., Lacko, A. G., Dory, L. & Fungwe, T. V., 13 Oct 2000, In : Journal of Nutrition. 130, 10, p. 2427-2433 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Hyperbaric oxygen reduces the progression and accelerates the regression of atherosclerosis in rabbits

Kudchodkar, B. J., Wilson, J., Lacko, A. & Dory, L., Jun 2000, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 20, 6, p. 1637-1643 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

International symposium on basic aspects of HDL metabolism and disease prevention

Lacko, A. G., Barter, P., Ehnholm, C. & Van Tol, A., 24 Oct 2000, In : Journal of Lipid Research. 41, 10, p. 1695-1699 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
1999

Enzyme linked immunoassay (ELISA) for lecithin:cholesterol acyltransferase (LCAT)

Murray, K. R., Nair, M. P., McConathy, W. J. & Lacko, A. G., 1 Jan 1999, In : Analytical Letters. 32, 8, p. 1553-1564 12 p.

Research output: Contribution to journalArticle

Evaluation of serum-lipid-related cardiovascular risk factors in Alzheimer's disease

Kálmán, J., Kudchodkar, B. J., Murray, K., McConathy, W. J., Juhász, A., Janka, Z. & Lacko, A. G., 12 Nov 1999, In : Dementia and Geriatric Cognitive Disorders. 10, 6, p. 488-493 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
1998

Characterization of recombinant human plasma lecithin: Cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

Lacko, A. G., Reason, A. J., Nuckolls, C., Kudchodkar, B. J., Nair, M. P., Sundarrajan, G., Pritchard, P. H., Morris, H. R. & Dell, A., 1 Apr 1998, In : Journal of Lipid Research. 39, 4, p. 807-820 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Decrease in high density lipoprotein cholesterol (HDL-C) levels following gemfibrozil therapy

Lacko, A. G., Kudchodkar, B. J., Loney, W. W., Clearfield, M. B. & Weis, S., 28 Aug 1998, In : Clinical Chemistry and Laboratory Medicine. 36, 6, p. 389-392 4 p.

Research output: Contribution to journalArticle

Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes

Fungwe, T. V., Kudchodkar, B. J., Lacko, A. G. & Dory, L., 1 Aug 1998, In : Journal of Nutrition. 128, 8, p. 1270-1275 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Lipoprotein substrate binding site of LCAT karen murray

Nair, M. P., Haydn Pritchard, P. & Lacko, A. G., 1 Dec 1998, In : FASEB Journal. 12, 8, p. A1379

Research output: Contribution to journalArticle

1997

Evaluation of gemfibrozil therapy: Predictive response from lipoprotein subfraction analysis

Loney, W. W., Kudchodkar, B. J., Weis, S., Clearfield, M. B., Shores, J. & Lacko, A. G., 1 Sep 1997, In : American Journal of Therapeutics. 4, 9-10, p. 301-309 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

International Symposium on the Role of HDL in Disease Prevention: Report on a meeting

Lacko, A. G. & Miller, N. E., 17 Jul 1997, In : Journal of Lipid Research. 38, 6, p. 1267-1273 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Purification of recombinant lecithin:cholesterol acyltransferase

Nair, M. P., Kudchodkar, B. J., Pritchard, P. H. & Lacko, A. G., Jun 1997, In : Protein Expression and Purification. 10, 1, p. 38-41 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

The expression of lecithin:Cholesterol acyltransferase is influenced by diet

Fungwe, T. V., Kudchodkar, B. J., Lacko, A. G. & Dory, L., 1 Dec 1997, In : FASEB Journal. 11, 3, p. A139

Research output: Contribution to journalArticle

1 Scopus citations
1996

Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine

Hasler-Rapacz, J., Kempen, H. J., Princen, H. M. G., Kudchodkar, B. J., Lacko, A. G. & Rapacz, J., 1 Jan 1996, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 16, 1, p. 137-143 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
1995

Effect of interfacial pressure on the binding and phospholipase A2 activity of recombinant human lecithin-cholesterol acyltransferase

Weinberg, R. B., Jones, J. B., Haydn Pritchard, P. & Lacko, A. G., 1 Jan 1995, In : Biochemical and Biophysical Research Communications. 211, 3, p. 840-846 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
1994

2nd International Symposium on Reverse Cholesterol Transport: Report on a meeting

Lacko, A. G. & Pritchard, P. H., 1 Jan 1994, In : Journal of Lipid Research. 35, 2, p. 351-356 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Plasma lipids and cholesterol esterification in Alzheimer's disease

Knebl, J., DeFazio, P., Clearfield, M. B., Little, L., McConathy, W. J., Mc Pherson, R. & Lacko, A. G., Jan 1994, In : Mechanisms of Ageing and Development. 73, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

The Effect of Captopril on the Oxidation of Plasma Lipoproteins

Clearfield, M. B., Lee, N., Armstrong, L., DeFazio, P., Kudchodkar, B. J. & Lacko, A. G., 1 Jan 1994, In : Pharmacology & Toxicology. 75, 3-4, p. 218-221 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
1993

Expression and characterization of recombinant human lecithin:cholesterol acyltransferase

Hill, J. S., Karmin, O., Wang, X., Paranjape, S., Dimitrijevich, D., Lacko, A. G. & Pritchard, P. H., 1 Jan 1993, In : Journal of Lipid Research. 34, 7, p. 1245-1251 7 p.

Research output: Contribution to journalArticle

32 Scopus citations
1992

Decreased lecithin: Cholesterol acyltransferase activity in the plasma of hypercholesterolemic pigs

Lacko, A. G., Lee, S. M., Mirshahi, I., Hasler-Rapacz, J. & Kudchodkar, B. J., 1 Apr 1992, In : Lipids. 27, 4, p. 266-269 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of ethinyl estradiol treatment on lipoproteins and LCAT activity in aged rats

Lee, S. M., Kudchodkar, B. J. & Lacko, A. G., Jun 1992, In : Mechanisms of Ageing and Development. 64, 1-2, p. 123-131 9 p.

Research output: Contribution to journalArticle

1 Scopus citations