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Personal profile

Area of Expertise

My research focuses on the development, characterization and application of nanotechnology based drug delivery systems that carry drugs to target sites in the body. The goal is to overcome the various therapeutic barriers using novel nano-platforms for the treatment of cancer and other diseases. My research centers on encapsulating various types of hydrophobic, hydrophilic, and small molecule drugs and imaging agents in nanoparticles and producing lab-scale and large-scale batches.
The three main areas of my research include:
1) Biomimetic drug delivery systems: bio-mimicking natures created by covering a polymeric nanoparticle with a cellular membrane extracted directly from cells;
2) Polymeric based nanoparticles: including the synthesis of targeted and non-targeted PLGA based nanoparticles. The targeting molecules such as peptides or antibodies may be attached using a linker which is either non-covalent or covalent to the polymeric or lipid surface using surface chemistry;
3) Curcumin Nano therapeutics: we have developed various nanoformulations using curcumin and are actively working to improve these nanoformulations to provide an effective way to deliver this drug.

Education/Academic qualification

PhD in Biochemical Engineering, IIT Delhi

MTech in Chemical Engineering, IIT Bombay

BS in Chemical Engineering, Birsa Institute of Tech-Sindri

Fingerprint Dive into the research topics where Amalendu Ranjan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Curcumin Medicine & Life Sciences
Nanoparticles Chemical Compounds
Antibodies Engineering & Materials Science
Neoplasms Medicine & Life Sciences
Tumors Engineering & Materials Science
Cells Engineering & Materials Science
Annexin A2 Chemical Compounds
Dissolved oxygen Engineering & Materials Science

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Projects 2013 2024

Research Output 2006 2019

  • 558 Citations
  • 12 h-Index
  • 28 Article
  • 3 Conference contribution
  • 3 Review article
  • 1 Conference article
Cell membranes
Brain
Coloring Agents
Dyes
Nanoparticles
3 Citations (Scopus)

Investigational agents to enhance the efficacy of chemotherapy or radiation in pancreatic cancer

Hurtado, M., Sankpal, U. T., Ranjan, A. P., Maram, R., Vishwanatha, J. K., Nagaraju, G. P., El-Rayes, B. F. & Basha, R. M., 1 Jun 2018, In : Critical Reviews in Oncology/Hematology. 126, p. 201-207 7 p.

Research output: Contribution to journalReview article

Pancreatic Neoplasms
Curcumin
Radiation
Drug Therapy
Non-Steroidal Anti-Inflammatory Agents
4 Citations (Scopus)

Optimization and scale up of microfluidic nanolipomer production method for preclinical and potential clinical trials

Gdowski, A., Johnson, K., Shah, S., Gryczynski, I., Vishwanatha, J. & Ranjan, A., 12 Feb 2018, In : Journal of Nanobiotechnology. 16, 1, 12.

Research output: Contribution to journalArticle

Microfluidics
Nanoparticles
Clinical Trials
Functional assessment
Curcumin
3 Citations (Scopus)

Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain

Gdowski, A. S., Ranjan, A. P., Sarker, M. R. & Vishwanatha, J. K., 1 Sep 2017, In : Nanomedicine. 12, 17, p. 2083-2095 13 p.

Research output: Contribution to journalArticle

lesion
Nanoparticles
pain
bone
cancer
12 Citations (Scopus)
Clinical Trials
Neoplasm Metastasis
Bone and Bones
Bone Neoplasms
Therapeutics