Projects per year
Personal profile
Research Interests
Signal Transduction, Cancer Biology, Protein kinase C. Akt, S6 kinase, Breast Cancer
Area of Expertise
We are using cellular, molecular, and biochemical approaches as well as state-of-the-art technologies, such as proteomics and genomics to determine how an intervention with a signaling pathway can be exploited for cancer therapy.
Another area of research is to investigate the molecular mechanism(s) of drug resistance. The ultimate goal of our research is to identify novel targets for cancer therapy, to exploit intracellular signaling systems to develop innovative strategies to treat cancer, and to identify potential biomarkers to predict patient response to cancer therapy.
Education/Academic qualification
MS in Biochemistry, University of Calcutta
Bachelor in Chemistry (with honors), University of Calcutta
PhD in Biochemistry, University of Pittsburgh School of Medicine
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Collaborations and top research areas from the last five years
Projects
- 13 Finished
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The involvement of S6 kinase 2 in breast cancer (For: Rohan Joshi)
Basu, A. (PI)
5/06/17 → 31/05/18
Project: Research
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Role of PKC-Epsilon in Autophagy in Breast Cancer (For: Kirti Jain)
Basu, A. (PI)
1/09/13 → 31/08/14
Project: Research
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Role and Regulation of S6 Kinase in Breast Cancer (For: Savitha Sridharan)
Basu, A. (PI)
1/09/13 → 31/08/14
Project: Research
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Protein Kinase C-eta Signaling in Breast Cancer (For: Deepanwita Pal)
Basu, A. (PI)
1/09/13 → 31/08/14
Project: Research
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Involvement of protein kinase C-δ in DNA damage-induced apoptosis
Basu, A., 2003, In: Journal of Cellular and Molecular Medicine. 7, 4, p. 341-350 10 p.Research output: Contribution to journal › Review article › peer-review
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The unique protein kinase Cη: Implications for breast cancer (Review)
Pal, D. & Basu, A., Aug 2014, In: International journal of oncology. 45, 2, p. 493-498 6 p.Research output: Contribution to journal › Review article › peer-review
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NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner
Shankar, E., Basu, C., Adkins, B., Siede, W. & Basu, A., 10 May 2010, In: Journal of Molecular Signaling. 5, 4.Research output: Contribution to journal › Article › peer-review
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Cellular Sensitization to m-Diamminedichloroplatinum(II) by Novel Analogues of the Protein Kinase C Activator Lyngbyatoxin A
Basu, A., Kozikowski, A. P., Sato, K. & Lazo, J. S., May 1991, In: Cancer Research. 51, 10, p. 2511-2514 4 p.Research output: Contribution to journal › Article › peer-review
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Comparison of protein kinase C activity and isoform expression in cisplatin‐sensitive and ‐resistant ovarian carcinoma cells
Basu, A. & Weixel, K. M., 9 Aug 1995, In: International Journal of Cancer. 62, 4, p. 457-460 4 p.Research output: Contribution to journal › Article › peer-review