• 417 Citations
  • 11 h-Index
19952020
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Personal profile

Area of Expertise

Very little is known about how and why the optic nerve is progressively damaged in glaucoma, a leading disease for blindness worldwide. Currently, glaucoma medication involves only pressure-lowering medication; however, vision loss continues. Conditions known to cause glaucoma, such as hypoxia and ischemia, were found to be associated with an increase in the expression of ASIC channels; blockers of such proteins increased survival of neurons in animals. Currently, my lab is involved in testing such blockers in different models of retinal injuries. Also, we are interested in steroid-induced trafficking in ocular tissues, which are known to cause glaucoma in ~ 30% of humans.

Education/Academic qualification

PhD in Biochemistry & Molecular Biology, UNT Health Science Center

BS in Chemistry, Kuwait University

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Projects 2013 2020

Research Output 1995 2019

  • 417 Citations
  • 11 h-Index
  • 32 Article
  • 2 Comment/debate
  • 2 Review article
  • 1 Short survey

Basics on the use of acid-sensing ion channels' inhibitors as therapeutics

Dibas, J., Al-Saad, H. & Dibas, A., 1 Mar 2019, In : Neural Regeneration Research. 14, 3, p. 395-398 4 p.

Research output: Contribution to journalReview articleResearchpeer-review

Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels
Drug Repositioning
Neuroprotective Agents
Blood-Retinal Barrier
2 Citations (Scopus)

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents

Stankowska, D. L., Mueller, B. H., Oku, H., Ikeda, T. & Dibas, A., 2 Jan 2018, In : Current Eye Research. 43, 1, p. 84-95 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Acid Sensing Ion Channel Blockers
Nerve Crush
Neuroprotective Agents
Optic Nerve
Acid Sensing Ion Channels
3 Citations (Scopus)

Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes

Dibas, A., Millar, J. C., Al-Farra, A. & Yorio, T., 3 Jul 2018, In : Current Eye Research. 43, 7, p. 921-933 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Acid Sensing Ion Channel Blockers
Retinal Ganglion Cells
Neuroprotective Agents
Reperfusion
Ischemia
3 Citations (Scopus)

CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation

Racine, R. R., Manalo, N. A., Hall, J. M. F., Dibas, A., Raffel, G. D. & Mummert, M. E., 1 Jul 2016, In : Biochemistry and Biophysics Reports. 6, p. 172-178 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphorylation
Cell proliferation
Phosphoric Monoester Hydrolases
Cell Proliferation
Calcium
14 Citations (Scopus)

Glucocorticoid therapy and ocular hypertension

Dibas, A. & Yorio, T., 1 Jan 2016, In : European Journal of Pharmacology. 787, p. 57-71 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Ocular Hypertension
Glucocorticoids
Macular Degeneration
Diabetic Retinopathy
Glaucoma