Abe Clark

Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head.

Clark, A. F., Kawase, K., English-Wright, S., Lane, D., Steely, H. T., Yamamoto, T., Kitazawa, Y., Kwon, Y. H., Fingert, J. H., Swiderski, R. E., Mullins, R. F., Hageman, G. S., Alward, W. L., Sheffield, V. C. & Stone, E. M., May 2001, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15, 7, p. 1251-1253 3 p.

Research output: Contribution to journal › Article › peer-review

Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells

Clark, A. F. & Capra, J. D., 1982, In: Journal of Experimental Medicine. 155, 2, p. 611-616 6 p.

Research output: Contribution to journal › Article › peer-review

Cross-linked actin networks (CLANs) are present in lamina cribrosa cells

Job, R., Raja, V., Grierson, I., Currie, L., O'Reilly, S., Pollock, N., Knight, E. & Clark, A. F., Oct 2010, In: British Journal of Ophthalmology. 94, 10, p. 1388-1392 5 p.

Research output: Contribution to journal › Article › peer-review

Prioritizing regions of candidate genes for efficient mutation screening

Braun, T. A., Shankar, S. P., Davis, S., O'Leary, B., Scheetz, T. E., Clark, A. F., Sheffield, V. C., Casavant, T. L. & Stone, E. M., Feb 2006, In: Human Mutation. 27, 2, p. 195-200 6 p.

Research output: Contribution to journal › Article › peer-review

Calcium channel blockade reduces mechanical strain-induced extracellular matrix gene response in lamina cribrosa cells

Quill, B., Irnaten, M., Docherty, N. G., McElnea, E. M., Wallace, D. M., Clark, A. F. & O'Brien, C. J., 1 Jul 2015, In: British Journal of Ophthalmology. 99, 7, p. 1009-1014 6 p.

Research output: Contribution to journal › Article › peer-review

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

Zode, G. S., Kuehn, M. H., Nishimura, D. Y., Searby, C. C., Mohan, K., Grozdanic, S. D., Bugge, K., Anderson, M. G., Clark, A. F., Stone, E. M. & Sheffield, V. C., 1 Sep 2011, In: Journal of Clinical Investigation. 121, 9, p. 3542-3553 12 p.

Research output: Contribution to journal › Article › peer-review

The effects of transforming growth factor-ß2 on the expression of follistatin and activin a in normal and glaucomatous human trabecular meshwork cells and tissues

Fitzgerald, A. M., Benz, C., Clark, A. F. & Wordinger, R. J., Oct 2012, In: Investigative Ophthalmology and Visual Science. 53, 11, p. 7358-7369 12 p.

Research output: Contribution to journal › Article › peer-review

In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Kim, B. J., Silverman, S. M., Liu, Y., Wordinger, R. J., Pang, I. H. & Clark, A. F., 21 Apr 2016, In: Molecular Neurodegeneration. 11, 1, 93.

Research output: Contribution to journal › Article › peer-review

Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma

Patil, S. V., Kaipa, B. R., Ranshing, S., Sundaresan, Y., Millar, J. C., Nagarajan, B., Kiehlbauch, C., Zhang, Q., Jain, A., Searby, C. C., Scheetz, T. E., Clark, A. F., Sheffield, V. C. & Zode, G. S., Dec 2024, In: Scientific Reports. 14, 1, 6958.

Research output: Contribution to journal › Article › peer-review

Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization

BenEzra, D., Griffin, B. W., Maftzir, G., Sharif, N. A. & Clark, A. F., Sep 1997, In: Investigative Ophthalmology and Visual Science. 38, 10, p. 1954-1962 9 p.

Research output: Contribution to journal › Article › peer-review

A magnetic bead-based method for mouse trabecular meshwork cell isolation.

Mao, W., Liu, Y., Wordinger, R. J. & Clark, A. F., May 2013, In: Unknown Journal. 54, 5, p. 3600-3606 7 p.

Research output: Contribution to journal › Article › peer-review

Aqueous humor outflow: What do we know? Where will it lead us?

Fautsch, M. P., Johnson, D. H., Acott, T. S., Aihara, M., Bhattacharya, S. K., Borrás, T., Camras, C. B., Civan, M. M., Clark, A. F., Crosson, C. E., Crowston, J. G., Epstein, D., Ethier, C. R., Freddo, T. F., Gong, H., Gonzalez, P., John, S. W., Johnson, M., Kaufman, P. L. & Knepper, P. A. & 30 others, Lindsey, J. D., Lütjen-Drecoll, E., Peters, D. M., Rao, P. V., Roy, S., Russell, P., Stamer, D., Tamm, E. R., Toris, C. B., Weinreb, R. N., Yue, B., Bornstein, P., Davies, P. F., Geiger, B., Kerjaschki, D., Mitchell, J., Schneeberger, E., Stitt, A., Zawieja, D. C., Bosworth, C., Grunden, J., Kim, E., Kopczynski, C., Krauss, A., Panjwani, N., Paterson, C., Prasanna, G., Rhee, D., Whitlock, A. & WuDunn, D., Oct 2006, In: Investigative Ophthalmology and Visual Science. 47, 10, p. 4181-4187 7 p.

Research output: Contribution to journal › Article › peer-review

The role of glia, mitochondria, and the immune system in glaucoma

Tezel, G., Ben-Hur, T., Gibson, G. E., Stevens, B., Streit, W. J., Wekerle, H., Bhattacharya, S. K., Borras, T., Burgoyne, C. F., Caspi, R. R., Chauhan, B. C., Clark, A. F., Crowston, J., Danias, J., Dick, A. D., Flammer, J., Foster, C. S., Grosskreutz, C. L., Grus, F. H. & Guy, J. & 48 others, Hernandez, M. R., Johnson, E., Kaplan, H. J., Kuehn, M. H., Lenaers, G., Levin, L. A., Lindsey, J. D., Malina, H., Nickells, R. W., Osborne, N., Quigley, H. A., Rao, N., Rosenbaum, J. T., Sadun, A. A., Schwartz, M., Sun, D., Trounce, I., Wax, M. B., Yorio, T., Abrams, G. W., Atherton, S. S., Boatright, J. H., Chu, J., Dowling, J., Ferris, F. L., Garway-Heath, D., Gregory, M., Grzybowski, D. M., Gupta, N., Inman, D., Ju, W. K., Kang, K. D., Kaufman, H. E., Kaufman, P. L., Larssen, L. I., Liebmann, J., Lupien, C., Miller, R. F., Niesman, M., O'Brien, C., Petrash, J. M., Prasanna, G., Ritch, R., Shestopalov, V., Wirostko, B., WoldeMussie, E., Yue, B. & Zimmerman, T. J., Mar 2009, In: Investigative Ophthalmology and Visual Science. 50, 3, p. 1001-1012 12 p.

Research output: Contribution to journal › Article › peer-review

Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the smad signaling pathway

Zode, G. S., Sethi, A., Brun-Zinkernagel, A. M., Chang, I. F., Clark, A. F. & Wordinger, R. J., 2011, In: Molecular vision. 17, p. 1745-1758 14 p.

Research output: Contribution to journal › Article › peer-review

Histological investigation of human glaucomatous eyes: Extracellular fibrotic changes and galectin 3 expression in the trabecular meshwork and optic nerve head

Belmares, R., Raychaudhuri, U., Maansson, S. & Clark, A. F., Oct 2018, In: Clinical Anatomy. 31, 7, p. 1031-1049 19 p.

Research output: Contribution to journal › Article › peer-review

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

Howell, G. R., Soto, I., Zhu, X., Ryan, M., Macalinao, D. G., Sousa, G. L., Caddle, L. B., MacNicoll, K. H., Barbay, J. M., Porciatti, V., Anderson, M. G., Smith, R. S., Clark, A. F., Libby, R. T. & John, S. W. M., 2 Apr 2012, In: Journal of Clinical Investigation. 122, 4, p. 1246-1261 16 p.

Research output: Contribution to journal › Article › peer-review

C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury

Silverman, S. M., Kim, B. J., Howell, G. R., Miller, J., John, S. W. M., Wordinger, R. J. & Clark, A. F., 24 Mar 2016, In: Molecular Neurodegeneration. 11, 1, 24.

Research output: Contribution to journal › Article › peer-review

Abe Clark, PhD

Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head.

Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells

Cross-linked actin networks (CLANs) are present in lamina cribrosa cells

Prioritizing regions of candidate genes for efficient mutation screening

Calcium channel blockade reduces mechanical strain-induced extracellular matrix gene response in lamina cribrosa cells

Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma

The effects of transforming growth factor-ß2 on the expression of follistatin and activin a in normal and glaucomatous human trabecular meshwork cells and tissues

In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma

Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization

A magnetic bead-based method for mouse trabecular meshwork cell isolation.

Aqueous humor outflow: What do we know? Where will it lead us?

The role of glia, mitochondria, and the immune system in glaucoma

Transforming growth factor-β2 increases extracellular matrix proteins in optic nerve head cells via activation of the smad signaling pathway

Histological investigation of human glaucomatous eyes: Extracellular fibrotic changes and galectin 3 expression in the trabecular meshwork and optic nerve head

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury

Lysyl oxidases in the trabecular meshwork

Basic sciences in clinical glaucoma: Steroids, ocular hypertension, and glaucoma

Human ocular perfusion organ culture: A versatile ex vivo model for glaucoma research

Acute effects of glaucoma medications on rat intraocular pressure

Abe Clark, PhD

Research output

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