Abe Clark, PhD

Research output

Research output per year 1979 1997 2001 2003 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2025

• 219 Article
• 20 Review article
• 11 Chapter
• 8 Short survey
• 13 More
  • 6 Editorial
  • 4 Comment/debate
  • 1 Book
  • 1 Foreword/postscript
  • 1 Letter

Research output per year

Research output per year

Search results

• The role of proteases in experimental glucocorticoid myopathy

  Clark, A. F. & Vignos, P. J., 1981, In: Muscle & Nerve. 4, 3, p. 219-222 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Protease 100%
  • Glucocorticoid Myopathy 100%
  • Glucocorticoid 100%
  • Leporidae 100%
  • Proteinase 100%

• Introduction to special issue on glaucomatous optic neuropathy: In vivo models and techniques

  Ethier, C. R., Morrison, J. C. & Clark, A. F., 20 Jul 2015, In: Experimental eye research. 141, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial

• Erratum: Reduced oxidative phosphorylation and increased glycolysis in human glaucoma lamina cribrosa cells ((Invest Ophthalmol Vis Sci. (2020) 61:13 (4) DOI: 10.1167/iovs.61.13.4)

  Kamel, K., O'Brien, C. J., Zhdanov, A. V., Papkovsky, D. B., Clark, A. F., Stamer, W. D. & Irnaten, M., Jan 2021, In: Investigative Ophthalmology and Visual Science. 62, 1, p. 1 1 p.

  Research output: Contribution to journal › Comment/debate

  • Author Names 100%
  • Human Glaucoma 100%
  • Lamina Cribrosa Cells 100%
  • Glycolysis 100%
  • Oxidative Phosphorylation (OXPHOS) 100%

• The effect of an angiostatic steroid on neovascularization in a rat model of retinopathy of prematurity

  Penn, J. S., Rajaratnam, V. S., Collier, R. J. & Clark, A. F., 2001, In: Investigative Ophthalmology and Visual Science. 42, 1, p. 283-290 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Rat Model 100%
  • Neovascularization 100%
  • Retinopathy of Prematurity 100%
  • Angiostatic 100%
  • Retrolental Fibroplasia 100%

• Inherited glaucoma in DBA/2J mice: Pertinent disease features for studying the neurodegeneration

  Libby, R. T., Anderson, M. G., Pang, I. H., Robinson, Z. H., Savinova, O. V., Cosma, I. M., Snow, A., Wilson, L. A., Smith, R. S., Clark, A. F. & John, S. W. M., Sep 2005, In: Visual Neuroscience. 22, 5, p. 637-648 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Glaucoma 100%
  • Disease Pattern 100%
  • Neurodegeneration 100%
  • Intraocular Pressure 80%
  • Elevated Intraocular Pressure 66%

• Glucocorticoid receptor transactivation is required for glucocorticoid-induced ocular hypertension and glaucoma

  Patel, G. C., Millar, J. C. & Clark, A. F., May 2019, In: Investigative Ophthalmology and Visual Science. 60, 6, p. 1967-1978 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Steroid-induced Ocular Hypertension 100%
  • Glaucoma 100%
  • Glucocorticoid Receptor 100%
  • Receptor Transactivation 100%
  • Glucocorticoid 100%

• The Eye as a Drug Target

  Yorio, T., Clark, A. F. & Wax, M. B., 2008, Ocular Therapeutics. Elsevier Ltd, p. 3-6 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Microfilament structure and microfilament protein expression in cultured dex ameth asonetreated and glaucomatous human trabecular meshwork (TM) cells

  Clark, A. F., Aboul-Ela, N. & English-Wright, S., 1997, In: Investigative Ophthalmology and Visual Science. 38, 4, p. S489

  Research output: Contribution to journal › Article › peer-review

  • Protein Expression 100%
  • Glaucomatous 100%
  • Trabecular Meshwork Cells 100%
  • Microfilaments 100%
  • Microfilament Proteins 100%

• The pathogenesis of retinal ganglia cell apoptosis induced by glaucoma

  Pang, I. H., Li, B. & Clark, A. F., Jul 2004, In: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 40, 7, p. 495-499 5 p.

  Research output: Contribution to journal › Review article › peer-review

• Steroid-induced glaucoma

  Clark, A. F., Zhang, X. & Yorio, T., 2010, Ocular Disease: Mechanisms and Management. Elsevier Inc., p. 146-152 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Acute effects of glaucoma medications on rat intraocular pressure

  Pang, I. H., Wang, W. H. & Clark, A. F., Feb 2005, In: Experimental eye research. 80, 2, p. 207-214 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Intraocular Pressure 100%
  • Acute Effects 100%
  • Glaucoma Medication 100%
  • Latanoprost 100%
  • Glaucoma 100%

• Importance of quantitative PCR primer location for short interfering RNA efficacy determination

  Shepard, A. R., Jacobson, N. & Clark, A. F., 15 Sep 2005, In: Analytical Biochemistry. 344, 2, p. 287-288 2 p.

  Research output: Contribution to journal › Article › peer-review

• Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells

  Kirwan, R. P., Wordinger, R. J., Clark, A. F. & O'Brien, C. J., 15 Jan 2009, In: Molecular vision. 15, p. 76-88 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Primary Open-angle Glaucoma 100%
  • Glaucomatous 100%
  • Extracellular Matrix 100%
  • Lamina Cribrosa Cells 100%
  • Gene Expression Pattern 100%

• The effect of dexamethasone on integrin and laminin expression in cultured human trabecular meshwork cells

  Dickerson, J. E., Steely, T. H., English-Wright, S. L. & Clark, A. F., Jun 1998, In: Experimental eye research. 66, 6, p. 731-738 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Trabecular Meshwork Cells 100%
  • Integrin 100%
  • Laminin 100%
  • Trabecular Meshwork 100%
  • Dexamethasone 100%

• Expression of matrix metalloproteinases and their inhibitors in human trabecular meshwork cells

  Pang, I. H., Hellberg, P. E., Fleenor, D. L., Jacobson, N. & Clark, A. F., 1 Aug 2003, In: Investigative Ophthalmology and Visual Science. 44, 8, p. 3485-3493 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-1β 100%
  • Trabecular Meshwork Cells 100%
  • Matrix Metalloproteinases 100%
  • Interleukin 1 100%
  • Tissue Inhibitor of Metalloproteinase 100%

• Steroid-lnduced cataract: New perspectives from in vitro and lens culture studies

  Dickerson, J. E., Dotzel, E. & Clark, A. F., Oct 1997, In: Experimental eye research. 65, 4, p. 507-516 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cataract 100%
  • In Vitro Culture 100%
  • Culture Studies 100%
  • Lens Culture 100%
  • Glucocorticoid 100%

• Steroid-induced ocular hypertension and effects of glucocorticoids on the trabecular meshwork

  Clark, A. F., 1 Jan 2010, Encyclopedia of the Eye. Elsevier, p. 219-223 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Steroid-induced Ocular Hypertension 100%
  • Trabecular Meshwork 100%
  • Ocular Effects 100%
  • Glucocorticoid 100%
  • Intraocular Hypertension 100%

• Altered expression of 3α-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes

  Agapova, O. A., Yang, P., Wang, W. H., Lane, D. A., Clark, A. F., Weinstein, B. I. & Hernandez, M. R., Oct 2003, In: Neurobiology of Disease. 14, 1, p. 63-73 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Glaucomatous 100%
  • Altered Expression 100%
  • Optic Nerve Head Astrocytes 100%
  • Hydroxysteroid Dehydrogenase 100%
  • Astrocyte 100%

• Preface

  Yorio, T., Clark, A. F. & Wax, M. B., 2008, Ocular Therapeutics. Elsevier Ltd, p. xv-xv

  Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

• Angiostatic activity of steroids in the chick embryo CAM and rabbit cornea models of neovascularization

  McNatt, L. G., Weimer, L., Yanni, J. & Clark, A. F., Oct 1999, In: Journal of Ocular Pharmacology and Therapeutics. 15, 5, p. 413-423 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neovascularization 100%
  • Rabbit Cornea 100%
  • Angiostatic 100%
  • Chick Embryo CAM 100%
  • Glucocorticoid 100%

• Involvement of AP-1 in interleukin-1α-stimulated MMP-3 expression in human trabecular meshwork cells

  Fleenor, D. L., Pang, I. H. & Clark, A. F., 1 Aug 2003, In: Investigative Ophthalmology and Visual Science. 44, 8, p. 3494-3501 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Activator protein-1 (AP-1) 100%
  • Interleukin-1β 100%
  • Trabecular Meshwork Cells 100%
  • Matrix metalloproteinase-3 (MMP-3) 100%
  • Transcription Factor AP 1 100%

• The cell and molecular biology of glaucoma: Biomechanical factors in glaucoma

  Clark, A. F., May 2012, In: Investigative Ophthalmology and Visual Science. 53, 5, p. 2473-2475 3 p.

  Research output: Contribution to journal › Article › peer-review

• Measurement of mouse intraocular pressure with the Tono-Pen [1]

  Pang, I. H., Wang, W. H., Millar, J. C. & Clark, A. F., Sep 2005, In: Experimental eye research. 81, 3, p. 359-360 2 p.

  Research output: Contribution to journal › Article › peer-review

• Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro

  Kirwan, R. P., Fenerty, C. H., Crean, J., Wordinger, R. J., Clark, A. F. & O'Brien, C. J., 23 Sep 2005, In: Molecular vision. 11, p. 798-810 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Lamina Cribrosa Cells 100%
  • Matrix Gene Expression 100%
  • Mechanical Strain 100%
  • Extracellular Matrix Genes 100%
  • Gene Expression 100%

• Tissue transglutaminase expression and activity in normal and glaucomatous human trabecular meshwork cells and tissues

  Tovar-Vidales, T., Roque, R., Clark, A. F. & Wordinger, R. J., Feb 2008, In: Investigative Ophthalmology and Visual Science. 49, 2, p. 622-628 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Glaucomatous 100%
  • Trabecular Meshwork Cells 100%
  • Tissue Transglutaminase 100%
  • TGM2 100%
  • Trabecular Meshwork 100%