UNT System College of Pharmacy

Research Output 1973 2020

1973
11 Citations (Scopus)

Interactions of the hexobarbital enantiomers with rat liver microsomes

Feller, D. R. & Lubawy, W. C., 1 Jan 1973, In : Pharmacology. 9, 3, p. 129-137 9 p.

Research output: Contribution to journalArticle

Hexobarbital
Liver Microsomes
Phenobarbital
Ethylmorphine
Microsomes

The effect of porcine somatotrophin (STH) on the hepatic proteins associated with drug metabolism in rats

Lubawy, W. C., Burkman, A. M., Feller, D. R. & Nelson, J. W., 1 Jan 1973, In : Federation Proceedings. 32, 3 (I), 1 p.

Research output: Contribution to journalArticle

Swine
Liver
Pharmaceutical Preparations
Proteins
1974
17 Citations (Scopus)

Anticonvulsant activity of 1‐alkyl‐4‐substituted 3,5‐pyrazolidinediones

Kornet, M. J., Thorstenson, J. H. & Lubawy, W. C., 1 Jan 1974, In : Journal of Pharmaceutical Sciences. 63, 7, p. 1090-1093 4 p.

Research output: Contribution to journalArticle

Monomethylhydrazine
Anticonvulsants
Seizures
Electroshock
Pentylenetetrazole
6 Citations (Scopus)

Cross inhibition of drug metabolism by drug metabolites. Increase of zoxazolamine paralysis time by the major metabolite of diphenylhydantoin

Lubawy, W. C., Kostenbauder, H. B. & Stavchansky, S. A., 1 Dec 1974, In : RES.COMMUN.CHEM.PATH.PHARMACOL.. 8, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Zoxazolamine
Enzyme inhibition
Phenytoin
Metabolites
Metabolism
9 Citations (Scopus)

Increase of hexobarbital sleeping time and inhibition of drug metabolism by the major metabolite of diphenylhydantoin

Stavchansky, S. A., Lubawy, W. C. & Kostenbauder, H. B., 16 Apr 1974, In : Life Sciences. 14, 8, p. 1535-1539 5 p.

Research output: Contribution to journalArticle

Hexobarbital
Enzyme inhibition
Phenytoin
Metabolites
Metabolism
1975
8 Citations (Scopus)

Antiarrhythmic activity of 3‐amino‐3‐methyloxindoles

Kornet, M. J., Thio, P. A., Malone, N. & Lubawy, W. C., 1 Jan 1975, In : Journal of Pharmaceutical Sciences. 64, 4, p. 639-642 4 p.

Research output: Contribution to journalArticle

Indoles
Lidocaine
Cardiac Arrhythmias
6 Citations (Scopus)

Kinetic and spectral studies of type I and type II compounds with rat hepatic microsomes in the presence of the major metabolite of diphenylhydantoin

Stavchansky, S. A., Kostenbauder, H. B. & Lubawy, W. C., 1 Dec 1975, In : Drug Metabolism and Disposition. 3, 6, p. 557-564 8 p.

Research output: Contribution to journalArticle

Phenytoin
Microsomes
Ethylmorphine
Liver
Hydroxylation
1976

Development of a drug education training course for school teachers.

Sherman, G. P. & Lubawy, W. C., 1 May 1976, In : American journal of pharmaceutical education. 40, 2, p. 161-164 4 p.

Research output: Contribution to journalArticle

Health Education
Curriculum
health promotion
Substance-Related Disorders
Teaching
24 Citations (Scopus)

Uptake and metabolism of nicotine by the isolated perfused rabbit lung

McGovern, J. P., Lubawy, W. C. & Kostenbauder, H. B., 1 Dec 1976, In : Journal of Pharmacology and Experimental Therapeutics. 199, 1, p. 198-207 10 p.

Research output: Contribution to journalArticle

Nicotine
Rabbits
Lung
Smoke
Tobacco
1977
2 Citations (Scopus)

An isolated perfused lung (IPL) smoke system for studying the inhibition of benzo(a)pyrene (BAP) metabolism by smoke

Lubawy, W. C., Griffith, R. B., Kostenbauder, H. B. & Perrier, D., 1 Jan 1977, In : Federation Proceedings. 36, 3, p. No.3697

Research output: Contribution to journalArticle

Benzo(a)pyrene
Smoke
Lung
18 Citations (Scopus)

Effects of aspirin and acetaminophen on fetal and placental growth in rats

Lubawy, W. C. & Garrett, R. J. B., Jan 1977, In : Journal of Pharmaceutical Sciences. 66, 1, p. 111-113 3 p.

Research output: Contribution to journalArticle

Acetaminophen
Fetal Development
Aspirin
Placenta
Fetus

In vivo and in vitro alteration of nicotine metabolism in the rat by the major metabolite of phenytoin

Lubawy, W. C., McGovern, J. P. & Kostenbauder, H. B., 1 Jan 1977, In : Pharmacologist. 19, 2, p. No. 477

Research output: Contribution to journalArticle

Phenytoin
Nicotine
In Vitro Techniques
90 Citations (Scopus)

Metalloimmunoassay

Cais, M., Dani, S., Eden, Y., Gandolfi, O., Horn, M., Isaacs, E. E., Josephy, Y., Saar, Y., Slovin, E. & Snarsky, L., 1 Dec 1977, In : Nature. 270, 5637, p. 534-535 2 p.

Research output: Contribution to journalArticle

Antigens
Radioisotopes
Haptens
Immunoassay
Isotopes
1978
2 Citations (Scopus)

Changes in serotonin contents in brain affect metabolic heat production of rabbits in cold

Lin, M. T., Pang, I. H., Chern, S. I. & Chia, W. Y., 1 Jan 1978, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 4, 1, p. R41-R47

Research output: Contribution to journalArticle

Thermogenesis
Serotonin
Rabbits
Brain
Temperature
23 Citations (Scopus)

Changes in serotonin contents in brain affect metabolic heat production of rabbits in cold.

Lin, M. T., Pang, I-H., Chern, S. I. & Chia, W. Y., 1 Jul 1978, In : The American journal of physiology. 235, 1

Research output: Contribution to journalArticle

Thermogenesis
Serotonin
Rabbits
Brain
Temperature
26 Citations (Scopus)

Effect of ketamine on thermoregulation in rats

Lin, M. T., Chen, C. F. & Pang, I-H., 1 Jan 1978, In : Canadian Journal of Physiology and Pharmacology. 56, 6, p. 963-967 5 p.

Research output: Contribution to journalArticle

Body Temperature Regulation
Ketamine
Thermogenesis
Temperature
Skin Temperature
6 Citations (Scopus)

Effects of 5,7‐dihydroxytryptamine and p‐chlorophenylalanine on temperature regulation in rats

Lin, M. T., Pang, I. H., Chern, Y. F. & Chern, S. I., Sep 1978, In : Journal of Pharmacy and Pharmacology. 30, 1, p. 723-725 3 p.

Research output: Contribution to journalArticle

Dihydroxytryptamines
Brain Chemistry
5,7-Dihydroxytryptamine
Fenclonine
Body Temperature Regulation
2 Citations (Scopus)

In vivo and in vitro alteration of nicotine metabolism by the major metabolite of phenytoin

Lubawy, W. C., Kostenbauder, H. B. & McGovren, J. P., 1 Jan 1978, In : Research Communications in Chemical Pathology and Pharmacology. 19, 2, p. 257-269 13 p.

Research output: Contribution to journalArticle

Phenytoin
Metabolites
Nicotine
Metabolism
Cotinine
38 Citations (Scopus)

Metalloimmunoassay. II. Iron-metallohaptens from estrogen steroids

Cais, M., Slovin, E. M. & Snarsky, L., 31 Oct 1978, In : Journal of Organometallic Chemistry. 160, 1, p. 223-230 8 p.

Research output: Contribution to journalArticle

estrogens
Estriol
steroids
Estrone
Estradiol
4 Citations (Scopus)

The effect of some cigarette smoke constituents and other compounds on the metabolism of benzo(a)pyrene in rabbit lung 9000 g supernatant

Hulshoff, A., Lubawy, W. C. & Kostenbauder, H. B., 1 Jan 1978, In : Xenobiotica. 8, 11, p. 711-717 7 p.

Research output: Contribution to journalArticle

Benzo(a)pyrene
Metabolism
Smoke
Tobacco Products
Benzopyrene Hydroxylase
1979
13 Citations (Scopus)

Coenzyme Q10 or α-tocopherol reduce the acute toxicity of anthramycin in mice

Lubawy, W. C., Whaley, J. & Hurley, L. H., 1 Jan 1979, In : Research Communications in Chemical Pathology and Pharmacology. 24, 2, p. 401-404 4 p.

Research output: Contribution to journalArticle

Benzodiazepinones
Anthramycin
Ubiquinone
Coenzymes
alpha-Tocopherol
8 Citations (Scopus)

Effects of increasing serotonergic receptor activity in brain on prostaglandin e1-induced fever in rabbits

Lin, M. T., Pang, I. H., Chern, S. I. & Chern, Y. F., 1 Jan 1979, In : Pharmacology. 18, 4, p. 188-194 7 p.

Research output: Contribution to journalArticle

Alprostadil
Serotonin
Fever
Rabbits
Brain

Immediate effect of cigarette smoke inhalation on 14C-benzopyrene metabolism in the isolated perfused rabbit lung

Isaac, R. S., Maggard, G. L. & Lubawy, W. C., 1 Jan 1979, In : Federation Proceedings. 38, 3 I

Research output: Contribution to journalArticle

Benzopyrenes
Smoke
Tobacco Products
Inhalation
Rabbits
35 Citations (Scopus)

In Vitro and in Vivo Stability of Anthramycin-DNA Conjugate and Its Potential Application as an Anthramycin Prodrug

Hurley, L. H., Allen, C. S. & Lubawy, W. C., Aug 1979, In : Cancer Research. 39, 8, p. 3134-3140 7 p.

Research output: Contribution to journalArticle

Anthramycin
DNA Adducts
Prodrugs
Pharmaceutical Preparations
DNA

Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Combined protective therapy with co-enzyme Q10 or vitamin E and the antitumor antibiotic anthramycin

Dallam, R. A., Lubawy, W. C. & Hurley, L. H., 1 Jan 1979, In : Journal of Natural Products. 42, 6, 1 p.

Research output: Contribution to journalArticle

Anthramycin
Vitamin E
Anti-Bacterial Agents
Enzymes
Therapeutics
Anthramycin
Prodrugs
Anti-Bacterial Agents
anthramycin-DNA
Bz-423
1980
12 Citations (Scopus)

Acute tobacco smoke exposure alters the profile of metabolites produced from benzo[a]pyrene by the isolated perfused rabbit lung

Lubawy, W. C. & Isaac, R. S., 1 Jan 1980, In : Toxicology. 18, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Tobacco
Benzo(a)pyrene
Metabolites
Smoke
Rabbits

An unusual movement disorder associated with neuroleptic treatment: Tardive dyskinesia?

White, K., Cohen, L. J. & Deandrea, D., Jul 1980, In : Journal of Nervous and Mental Disease. 168, 7, p. 442-444 3 p.

Research output: Contribution to journalArticle

Movement Disorders
Antipsychotic Agents
Dissent and Disputes
Therapeutics
Nervous System Diseases
26 Citations (Scopus)

Drug withdrawal syndromes. A literature review

Hodding, G. C., Jann, M. W. & Ackerman, I. P., 1 Dec 1980, In : Western Journal of Medicine. 133, 5, p. 383-391 9 p.

Research output: Contribution to journalReview article

Substance Withdrawal Syndrome
Psychotropic Drugs
Narcotics
Clonidine
Propranolol
8 Citations (Scopus)

Influence of pretreatment with tobacco smoke condensate or 3-methylcholanthrene on [14C] benzo (A) pyrene metabolism in the isolated perfused rabbit lung

Lubawy, W. C. & Isaac, R. S., Dec 1980, In : Toxicology Letters. 7, 2, p. 153-159 7 p.

Research output: Contribution to journalArticle

Methylcholanthrene
Tobacco
Metabolism
Smoke
Rabbits
12 Citations (Scopus)

Protection against anthramycin-induced toxicity in mice by coenzyme Q10

Lubawy, W. C., Dallam, R. A. & Hurley, L. H., 1 Jan 1980, In : Journal of the National Cancer Institute. 64, 1, p. 105-109 5 p.

Research output: Contribution to journalArticle

coenzyme Q10
Anthramycin
Heart Neoplasms
Radioactivity
Spleen
9 Citations (Scopus)

The effect of acute tobacco smoke exposure on pulmonary benzo[a]pyrene metabolism

Lubawy, W. C. & Perrier, D. G., Apr 1980, In : Environmental Research. 21, 2, p. 438-445 8 p.

Research output: Contribution to journalArticle

Tobacco
Benzo(a)pyrene
pyrene
Metabolism
Smoke
1982
1 Citation (Scopus)

Arachidonic acid metabolism in isolated perfused lungs, platelets and aorta from streptozocin pretreated rats

Valentovic, A. & Lubawy, W. C., 1 Jan 1982, In : Federation Proceedings. 41, 4, 1 p.

Research output: Contribution to journalArticle

Streptozocin
Arachidonic Acid
Aorta
Blood Platelets
Lung

Effect of adriamycin on drug biotransformation and lipid peroxidation in vitamin E deficient rats

Atkinson, J. E., Gairola, C. & Lubawy, W. C., 1 Jan 1982, In : Federation Proceedings. 41, 4, 1 p.

Research output: Contribution to journalArticle

Biotransformation
Vitamin E
Doxorubicin
Lipid Peroxidation
Pharmaceutical Preparations

Hydroxyhaloperidol plasma levels in nonresponding schizophrenics

Ereshefsky, L., Jann, M. W., Saklad, S. R. & Davis, C. M., 1 Jan 1982, In : Drug Intelligence and Clinical Pharmacy. 16, 6, p. No. 20

Research output: Contribution to journalArticle

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
35 Citations (Scopus)

Lithium prophylaxis of tricyclic-antidepressant-induced mania in bipolar patients

Jann, M. W., Bitar, A. H. & Rao, A., 1 Jan 1982, In : American Journal of Psychiatry. 139, 5, p. 683-684 2 p.

Research output: Contribution to journalArticle

Tricyclic Antidepressive Agents
Bipolar Disorder
Lithium
Depression
Serum
23 Citations (Scopus)

Lung, aorta, and platelet metabolism of 14C-arachidonic acid in vitamin E deficient rats

Valentovic, M. A., Gairola, C. & Lubawy, W. C., Aug 1982, In : Prostaglandins. 24, 2, p. 215-224 10 p.

Research output: Contribution to journalArticle

Platelets
Vitamin E
Arachidonic Acid
Metabolism
Aorta

Physical, chemical and physiological factors influencing entry of xenobiotics into the body via the pulmonary system

Lubawy, W. C., Jul 1982, In : Environmental Toxicology and Chemistry. 1, 3, p. 221-230 10 p.

Research output: Contribution to journalReview article

Xenobiotics
xenobiotics
lipid
Lipids
Lung
11 Citations (Scopus)

Respiratory dyskinesia

Jann, M. W. & Bitar, A. H., 1 Jan 1982, In : Psychosomatics. 23, 7, p. 764-765 2 p.

Research output: Contribution to journalLetter

17 Citations (Scopus)

Streptozocin-induced diabetes decreases formation of prostacyclin from arachidonic acid in intact rat lungs

Lubawy, W. C. & Valentovic, M., Dec 1982, In : Biochemical medicine. 28, 3, p. 290-297 8 p.

Research output: Contribution to journalArticle

Experimental Diabetes Mellitus
Epoprostenol
Streptozocin
Medical problems
Arachidonic Acid
1983

Acute treatment with pyrrolo(1,4)benzodiazepine antitumor antibiotics alters in vitro hepatic drug metabolizing activity in rats

Atkinson, J. E. & Lubawy, W. C., 1 Jan 1983, In : Toxicology Letters. 18, 3, p. 337-342 6 p.

Research output: Contribution to journalArticle

Anthramycin
Rats
Metabolism
Doxorubicin
Anti-Bacterial Agents
20 Citations (Scopus)

Chronic cigarette smoke exposure adversely alters 14C-arachidonic acid metabolism in rat lungs, aortas and platelets

Lubawy, W. C., Valentovic, M. A., Atkinson, J. E. & Gairola, G. C., 8 Aug 1983, In : Life Sciences. 33, 6, p. 577-584 8 p.

Research output: Contribution to journalArticle

Platelets
Arachidonic Acid
Metabolism
Smoke
Tobacco Products
7 Citations (Scopus)

Evidence against involvement of β-endorphin in thermoregulation in the cat

Clark, W. G., Pang, I-H. & Bernardini, G. L., 1 Jan 1983, In : Pharmacology, Biochemistry and Behavior. 18, 5, p. 741-745 5 p.

Research output: Contribution to journalArticle

Endorphins
Body Temperature Regulation
Naloxone
Cats
Temperature
30 Citations (Scopus)
Tolbutamide
Thromboxanes
Epoprostenol
Streptozocin
Arachidonic Acid
4 Citations (Scopus)

Increasing lipid peroxidation by vitamin E deficiency does not augment adriamycin-induced inhibition of hepatic drug metabolism

Atkinson, J. E., Gairola, C. C. & Lubawy, W. C., Dec 1983, In : Toxicology. 29, 1-2, p. 121-129 9 p.

Research output: Contribution to journalArticle

Vitamin E Deficiency
Enzyme inhibition
Vitamin E
Metabolism
Doxorubicin
3 Citations (Scopus)

Metabolism of isosorbide dinitrate in the isolated perfused rabbit lung

Mayer, P. R., Lubawy, W. C., McNamara, P. J. & Kostenbauder, H. B., Jul 1983, In : Journal of Pharmaceutical Sciences. 72, 7, p. 785-789 5 p.

Research output: Contribution to journalArticle

Isosorbide Dinitrate
Rabbits
Lung
Isosorbide
isosorbide-5-mononitrate

The authors reply

Jann, M. W., Saklad, S. R. & Bitar, A. H., 1 Jan 1983, In : Psychosomatics. 24, 2, 1 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)

The genetic activity of anthramycin, tomaymycin and sibiromycin in bacterial forward‐ and reverse‐mutation assays and in the mouse bone‐marrow micronucleus test

Gairola, C., Thomas, H., Szeinbach, S. L. & Lubawy, W. C., Dec 1983, In : Journal of Applied Toxicology. 3, 6, p. 317-320 4 p.

Research output: Contribution to journalArticle

Anthramycin
Micronucleus Tests
Salmonella
Assays
Pharmaceutical Preparations
1984

Active and passive cigarette smoking influence aortic PGI2 and platelet TXA2 synthesis in female rats

Valentovic, M. A. & Lubawy, W. C., 1 Dec 1984, In : Research Communications in Substances of Abuse. 5, 3, p. 233-240 8 p.

Research output: Contribution to journalArticle

Tobacco Smoke Pollution
Epoprostenol
Smoke
Blood Platelets
Smoking
4 Citations (Scopus)

Alternative drug therapies for mania: A literature review

Jann, M. W., Garrelts, J. C., Ereshefsky, L. & Saklad, S. R., 1 Jan 1984, In : Drug Intelligence and Clinical Pharmacy. 18, 7-8, p. 577-589 13 p.

Research output: Contribution to journalReview article

Complementary Therapies
Bipolar Disorder
Drug Therapy
Clorgyline
Carbamazepine