Research Output

Filter
Review article
2020

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-6

Vanden Eynde, J. J., Mangoni, A. A., Rautio, J., Leprince, J., Azuma, Y. T., García-Sosa, A. T., Hulme, C., Jampilek, J., Karaman, R., Li, W., Gomes, P. A. C., Hadjipavlou-Litina, D., Capasso, R., Geronikaki, A., Cerchia, L., Sabatier, J. M., Ragno, R., Tuccinardi, T., Trabocchi, A., Winum, J. Y. & 22 others, Luque, F. J., Prokai-Tatrai, K., Spetea, M., Gütschow, M., Kosalec, I., Guillou, C., Vasconcelos, M. H., Kokotos, G., Rastelli, G., De Sousa, M. E., Manera, C., Gemma, S., Mangani, S., Siciliano, C., Galdiero, S., Liu, H., Scott, P. J. H., De Los Ríos, C., Agrofoglio, L. A., Collina, S., Guedes, R. C. & Muñoz-Torrero, D., 1 Jan 2020, In : Molecules. 25, 1, 119.

Research output: Contribution to journalReview article

Open Access

Inducible rodent models of glaucoma

Pang, I. H. & Clark, A. F., Mar 2020, In : Progress in Retinal and Eye Research. 75, 100799.

Research output: Contribution to journalReview article

1 Scopus citations

Long-term HIV-1 Tat Expression in the Brain Led to Neurobehavioral, Pathological, and Epigenetic Changes Reminiscent of Accelerated Aging

Zhao, X., Fan, Y., Vann, P. H., Wong, J. M., Sumien, N. & He, J. J., 1 Feb 2020, In : Aging and Disease. 11, 1, p. 93-107 15 p.

Research output: Contribution to journalReview article

Open Access

Metformin and cognition from the perspectives of sex, age, and disease

Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Feb 2020, In : GeroScience. 42, 1, p. 97-116 20 p.

Research output: Contribution to journalReview article

2019

Basics on the use of acid-sensing ion channels' inhibitors as therapeutics

Dibas, J., Al-Saad, H. & Dibas, A., Mar 2019, In : Neural Regeneration Research. 14, 3, p. 395-398 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Blood-based biomarkers for Down syndrome and Alzheimer's disease: A systematic review

Petersen, M. E. & O'Bryant, S. E., 1 Jul 2019, In : Developmental Neurobiology. 79, 7, p. 699-710 12 p.

Research output: Contribution to journalReview article

3 Scopus citations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 others, Gütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 1, p. 1-12 12 p.

Research output: Contribution to journalReview article

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5

Mangoni, A. A., Eynde, J. J. V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M. E., Gomes, P. A. C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J. M., Luque, F. J., Rautio, J., Karaman, R., Vasconcelos, M. H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., Gütschow, M. & 6 others, Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L. A., Ragno, R. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 13, 2415.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Models of poststroke depression and assessments of core depressive symptoms in rodents: How to choose?

Tao, X., Yang, W., Zhu, S., Que, R., Liu, C., Fan, T., Wang, J., Mo, D., Zhang, Z., Tan, J., Jin, K., Yenarih, M. A., Song, T. & Wang, Q., Dec 2019, In : Experimental Neurology. 322, 113060.

Research output: Contribution to journalReview article

1 Scopus citations

Remote ischemic conditioning for stroke: clinical data, challenges, and future directions

Zhao, W., Li, S., Ren, C., Meng, R., Jin, K. & Ji, X., Jan 2019, In : Annals of Clinical and Translational Neurology. 6, 1, p. 186-196 11 p.

Research output: Contribution to journalReview article

4 Scopus citations

Systemic milieu and age-related deterioration

Zhang, H., Cherian, R. & Jin, K., 15 Jun 2019, In : GeroScience. 41, 3, p. 275-284 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

The effect of age, sex and strains on the performance and outcome in animal models of stroke

Zhang, H., Lin, S., Chen, X., Gu, L., Zhu, X., Zhang, Y., Reyes, K., Wang, B. & Jin, K., Jul 2019, In : Neurochemistry International. 127, p. 2-11 10 p.

Research output: Contribution to journalReview article

3 Scopus citations
2018

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

Martins, R. N., Villemagne, V., Sohrabi, H. R., Chatterjee, P., Shah, T. M., Verdile, G., Fraser, P., Taddei, K., Gupta, V. B., Rainey-Smith, S. R., Hone, E., Pedrini, S., Lim, W. L., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K. & 17 others, Fuller, S. J., Brown, B., Gardener, S. L., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S. M., Barron, A. M., Goozee, K., Wahjoepramono, E. J., Asih, P. R., Doecke, J. D., Salvado, O., Bush, A. I., Rowe, C. C., Gandy, S. E. & Masters, C. L., 1 Jan 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 965-992 28 p.

Research output: Contribution to journalReview article

19 Scopus citations

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

Hampel, H., O’Bryant, S. E., Molinuevo, J. L., Zetterberg, H., Masters, C. L., Lista, S., Kiddle, S. J., Batrla, R. & Blennow, K., 1 Nov 2018, In : Nature Reviews Neurology. 14, 11, p. 639-652 14 p.

Research output: Contribution to journalReview article

54 Scopus citations

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut, 19 May 2018, In : World Journal of Biological Psychiatry. 19, 4, p. 244-328 85 p.

Research output: Contribution to journalReview article

66 Scopus citations

Glia–immune interactions post-ischemic stroke and potential therapies

Hersh, J. & Yang, S. H., 1 Dec 2018, In : Experimental Biology and Medicine. 243, 17-18, p. 1302-1312 11 p.

Research output: Contribution to journalReview article

1 Scopus citations
4 Scopus citations

Oncolytic virotherapy for breast cancer treatment

O’bryan, S. M. & Mathis, J. M., 1 Jan 2018, In : Current Gene Therapy. 18, 4, p. 192-205 14 p.

Research output: Contribution to journalReview article

3 Scopus citations

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

INSIGHT-preAD Study Group & the Alzheimer Precision Medicine Initiative (APMI), Sep 2018, In : Alzheimer's and Dementia. 14, 9, p. 1204-1215 12 p.

Research output: Contribution to journalReview article

16 Scopus citations

Tyrosine hydroxylase as a sentinel for central and peripheral tissue responses in Parkinson's progression: Evidence from clinical studies and neurotoxin models

Johnson, M. E., Salvatore, M. F., Maiolo, S. A. & Bobrovskaya, L., 1 Jun 2018, In : Progress in Neurobiology. 165-167, p. 1-25 25 p.

Research output: Contribution to journalReview article

7 Scopus citations
2017

Age-related impairment of vascular structure and functions

Xu, X., Wang, B., Ren, C., Hu, J., Greenberg, D. A., Chen, T., Xie, L. & Jin, K., 1 Oct 2017, In : Aging and Disease. 8, 5, p. 590-610 21 p.

Research output: Contribution to journalReview article

37 Scopus citations
23 Scopus citations

A Precision Medicine Initiative for Alzheimer’s disease: the road ahead to biomarker-guided integrative disease modeling

for the Alzheimer Precision Medicine Initiative, 4 Mar 2017, In : Climacteric. 20, 2, p. 107-118 12 p.

Research output: Contribution to journalReview article

55 Scopus citations

Cross-linked actin networks (CLANs) in glaucoma

Bermudez, J. Y., Montecchi-Palmer, M., Mao, W. & Clark, A. F., 1 Jun 2017, In : Experimental eye research. 159, p. 16-22 7 p.

Research output: Contribution to journalReview article

12 Scopus citations

Impact of aging immune system on neurodegeneration and potential immunotherapies

Liang, Z., Zhao, Y., Ruan, L., Zhu, L., Jin, K., Zhuge, Q., Su, D. M. & Zhao, Y., Oct 2017, In : Progress in Neurobiology. 157, p. 2-28 27 p.

Research output: Contribution to journalReview article

14 Scopus citations

Involvement of Nrf2 in ocular diseases

Batliwala, S., Xavier, C., Liu, Y., Wu, H. & Pang, I. H., 1 Jan 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 1703810.

Research output: Contribution to journalReview article

18 Scopus citations

Recent progress in vascular aging: Mechanisms and its role in age-related diseases

Xu, X., Wang, B., Ren, C., Hu, J., Greenberg, D. A., Chen, T., Xie, L. & Jin, K., 1 Jan 2017, In : Aging and Disease. 8, 4, 0507.

Research output: Contribution to journalReview article

20 Scopus citations

The many faces of the trabecular meshwork cell

Stamer, W. D. & Clark, A. F., 1 May 2017, In : Experimental eye research. 158, p. 112-123 12 p.

Research output: Contribution to journalReview article

39 Scopus citations

The roles of oncogenic miRNAs and their therapeutic importance in breast cancer

O'Bryan, S., Dong, S., Mathis, J. M. & Alahari, S. K., 1 Feb 2017, In : European Journal of Cancer. 72, p. 1-11 11 p.

Research output: Contribution to journalReview article

43 Scopus citations
2016

Brain globins in physiology and pathology

Xie, L. K. & Yang, S. H., 1 Jul 2016, In : Medical Gas Research. 6, 3, p. 154-163 10 p.

Research output: Contribution to journalReview article

10 Scopus citations

From the 90's to now: A brief historical perspective on more than two decades of estrogen neuroprotection

Engler-Chiurazzi, E. B., Singh, M. & Simpkins, J. W., 15 Feb 2016, In : Brain Research. 1633, p. 96-100 5 p.

Research output: Contribution to journalReview article

28 Scopus citations

Neuropharmacology of N,N-dimethyltryptamine

Carbonaro, T. M. & Gatch, M. B., 1 Sep 2016, In : Brain Research Bulletin. 126, p. 74-88 15 p.

Research output: Contribution to journalReview article

25 Scopus citations

Novel therapeutic targets for reduction of intraocular pressure in primary open angle glaucoma

Mao, W., Liu, Y., Wordinger, R. J., Clark, A. F. & Pang, I. H., 11 Jun 2016, In : Chinese Journal of Ophthalmology. 52, 6, p. 471-475 5 p.

Research output: Contribution to journalReview article

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

Proceedings of the Meeting of the International Working Group (IWG) and the American Alzheimer's Association on "The Preclinical State of AD"; July 23, 2015; Washington DC, USA, 1 Mar 2016, In : Alzheimer's and Dementia. 12, 3, p. 292-323 32 p.

Research output: Contribution to journalReview article

439 Scopus citations

Reprint of: From the 90׳s to now: A brief historical perspective on more than two decades of estrogen neuroprotection

Engler-Chiurazzi, E. B., Singh, M. & Simpkins, J. W., 15 Aug 2016, In : Brain Research. 1645, p. 79-82 4 p.

Research output: Contribution to journalReview article

11 Scopus citations
2015

Alcohol withdrawal and cerebellar mitochondria

Jung, E., 1 Aug 2015, In : Cerebellum. 14, 4, p. 421-437 17 p., A001.

Research output: Contribution to journalReview article

13 Scopus citations

Biomarkers in Sporadic and Familial Alzheimer's Disease

Lista, S., O'Bryant, S. E., Blennow, K., Dubois, B., Hugon, J., Zetterberg, H. & Hampel, H., 24 Jul 2015, In : Journal of Alzheimer's Disease. 47, 2, p. 291-317 27 p.

Research output: Contribution to journalReview article

41 Scopus citations

Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline

Lista, S., Molinuevo, J. L., Cavedo, E., Rami, L., Amouyel, P., Teipel, S. J., Garaci, F., Toschi, N., Habert, M. O., Blennow, K., Zetterberg, H., O'Bryant, S. E., Johnson, L., Galluzzi, S., Bokde, A. L. W., Broich, K., Herholz, K., Bakardjian, H., Dubois, B., Jessen, F. & 3 others, Carrillo, M. C., Aisen, P. S. & Hampel, H., 24 Sep 2015, In : Journal of Alzheimer's Disease. 48, S1, p. S171-S191

Research output: Contribution to journalReview article

21 Scopus citations

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

O'Bryant, S. E., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J. Q., Schupf, N. & 8 others, Rissman, R. A., Fagan, A. M., Oberoi, P., Umek, R., Weiner, M. W., Grammas, P., Posner, H. & Martins, R., 1 May 2015, In : Alzheimer's and Dementia. 11, 5, p. 549-560 12 p.

Research output: Contribution to journalReview article

93 Scopus citations

HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads

Borgmann, K. & Ghorpade, A., 1 Jan 2015, In : Frontiers in Microbiology. 6, OCT, 1143.

Research output: Contribution to journalReview article

18 Scopus citations

Innovative diagnostic tools for early detection of Alzheimer's disease

Laske, C., Sohrabi, H. R., Frost, S. M., López-De-Ipiña, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S. R., Mueller, S., Linnemann, C., Bridenbaugh, S. A., Kanagasingam, Y., Martins, R. N. & O'bryant, S. E., 1 May 2015, In : Alzheimer's and Dementia. 11, 5, p. 561-578 18 p.

Research output: Contribution to journalReview article

101 Scopus citations

Interaction of astrocytes and T cells in physiological and pathological conditions

Xie, L. & Yang, S., 1 Jan 2015, In : Brain Research. 1623, p. 63-73 11 p.

Research output: Contribution to journalReview article

25 Scopus citations

Therapeutic potential of cancer stem cells

Yang, C., Jin, K., Tong, Y. & Cho, W. C., 1 May 2015, In : Medical Oncology. 32, 6

Research output: Contribution to journalReview article

17 Scopus citations
2014

MDM2 inhibitors in the search for an optimized neovascular age-related macular degeneration treatment

Kon Graversen, V. & Chavala, S. H., 1 Oct 2014, In : Expert Review of Ophthalmology. 9, 5, p. 355-359 5 p.

Research output: Contribution to journalReview article

1 Scopus citations

Neurogenesis in neurological and psychiatric diseases and brain injury: From bench to bedside

Ruan, L., Lau, B. W. M., Wang, J., Huang, L., ZhuGe, Q., Wang, B., Jin, K. & So, K. F., 1 Jan 2014, In : Progress in Neurobiology. 115, C, p. 116-137 22 p.

Research output: Contribution to journalReview article

48 Scopus citations

Role of the alternatively spliced glucocorticoid receptor isoform GRβ in steroid responsiveness and glaucoma

Jain, A., Wordinger, R. J., Yorio, T. & Clark, A. F., 1 Mar 2014, In : Journal of Ocular Pharmacology and Therapeutics. 30, 2-3, p. 121-127 7 p.

Research output: Contribution to journalReview article

14 Scopus citations

Sex differences in cognitive impairment and Alzheimer's disease

Li, R. & Singh, M., Aug 2014, In : Frontiers in Neuroendocrinology. 35, 3, p. 385-403 19 p.

Research output: Contribution to journalReview article

142 Scopus citations

The future of blood-based biomarkers for Alzheimer's disease

Henriksen, K., O'Bryant, S. E., Hampel, H., Trojanowski, J. Q., Montine, T. J., Jeromin, A., Blennow, K., Lönneborg, A., Wyss-Coray, T., Soares, H., Bazenet, C., Sjögren, M., Hu, W., Lovestone, S., Karsdal, M. A. & Weiner, M. W., 1 Jan 2014, In : Alzheimer's and Dementia. 10, 1, p. 115-131 17 p.

Research output: Contribution to journalReview article

148 Scopus citations

The role of TGF-β2 and bone morphogenetic proteins in the trabecular meshwork and glaucoma

Wordinger, R. J., Sharma, T. & Clark, A. F., 1 Mar 2014, In : Journal of Ocular Pharmacology and Therapeutics. 30, 2-3, p. 154-162 9 p.

Research output: Contribution to journalReview article

41 Scopus citations
2013

Challenges in the development of glaucoma neuroprotection therapy

Liu, Y. & Pang, I-H., 1 Aug 2013, In : Cell and Tissue Research. 353, 2, p. 253-260 8 p.

Research output: Contribution to journalReview article

10 Scopus citations