Pharmacology & Neuroscience

Research output

Research output per year 1973 2001 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 113888 Citations
• 145 h-index
• 2000 Article
• 173 Review article
• 48 Chapter
• 48 Comment/debate
• 74 More
  • 27 Editorial
  • 19 Short survey
  • 11 Letter
  • 10 Conference contribution
  • 2 Book
  • 2 Foreword/postscript
  • 2 Conference article
  • 1 Paper

Research output per year

Research output per year

Search results

• 2017

  Presence of androgen receptor variant in neuronal lipid rafts

  Garza-Contreras, J., Duong, P., Snyder, B. D., Schreihofer, D. A. & Cunningham, R. L., 1 Jul 2017, In: eNeuro. 4, 4, e0109-17.2017.

  Research output: Contribution to journal › Article › peer-review

  • Androgen Receptors 100%
  • Membrane Lipids 68%
  • Dopaminergic Neurons 64%
  • Lipids 60%
  • Androgens 56%
  16 Scopus citations

• Protective roles for RGS2 in a mouse model of house dust mite-induced airway inflammation

  George, T., Bell, M., Chakraborty, M., Siderovski, D. P., Giembycz, M. A. & Newton, R., Jan 2017, In: PLoS ONE. 12, 1, e0170269.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GTP-Binding Protein Regulators 100%
  • dust mites 88%
  • Pyroglyphidae 85%
  • Dust 73%
  • G-proteins 70%
  17 Scopus citations

• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

  Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., & 426 othersHoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., 1 Sep 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Frequency 100%
  • Innate Immunity 94%
  • Alzheimer Disease 79%
  • Microglia 34%
  • Odds Ratio 32%
  514 Scopus citations

• Retrograde conditioning of place preference and motor activity with cocaine in mice

  Shetty, R. A., Rutledge, M. A. & Forster, M. J., 1 Feb 2017, In: Psychopharmacology. 234, 3, p. 515-522 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Methamphetamine 100%
  • Motor Activity 90%
  • Cocaine 85%
  • Pharmaceutical Preparations 23%
  • Memory 20%
  3 Scopus citations

• Role of ID proteins in BMP4 inhibition of profibrotic effects of TGF-β2 in human TM cells

  Mody, A. A., Wordinger, R. J. & Clark, A. F., 1 Feb 2017, In: Investigative Ophthalmology and Visual Science. 58, 2, p. 849-859 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Trabecular Meshwork 100%
  • Proteins 27%
  • Plasminogen Activator Inhibitor 1 16%
  • Fibronectins 14%
  • Inhibitor of Differentiation Protein 1 14%
  18 Scopus citations

• Serum YKL-40, a prognostic marker in patients with large-artery atherosclerotic stroke

  Chen, X. L., Li, Q., Huang, W. S., Lin, Y. S., Xue, J., Wang, B., Jin, K. L. & Shao, B., Aug 2017, In: Acta Neurologica Scandinavica. 136, 2, p. 97-102 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atherosclerosis 100%
  • Arteries 91%
  • Stroke 84%
  • Serum 56%
  • Biomarkers 26%
  12 Scopus citations

• Soluble lectin-like oxidized low-density lipoprotein receptor-1 as a novel biomarker for large-artery atherosclerotic stroke

  Huang, W., Li, Q., Chen, X., Lin, Y., Xue, J., Cai, Z., Zhang, W., Wang, H., Jin, K. & Shao, B., 3 Oct 2017, In: International Journal of Neuroscience. 127, 10, p. 881-886 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Class E Scavenger Receptors 100%
  • Arteries 46%
  • Stroke 42%
  • Biomarkers 40%
  • Serum 21%
  11 Scopus citations

• Study on CT perfusion surface permeability of cerebral hemorrhage in the basal ganglia region in subacute stage

  Wang, J., Xu, H., Liu, S., Zhang, Y., Liu, J., He, W., Qin, X., Yang, Y., Zhuge, Q., Jin, K. & Chen, W., 8 Mar 2017, In: Chinese Journal of Neurology. 50, 3, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cerebral Hemorrhage 100%
  • Basal Ganglia 94%
  • Permeability 79%
  • Perfusion 70%
  • Perfusion Imaging 50%

• Targeting alpha toxin to mitigate its lethal toxicity in ferret and rabbit models of Staphylococcus aureus necrotizing pneumonia

  Diep, B. A., Hilliard, J. J., Le, V. T. M., Tkaczyk, C., Le, H. N., Tran, V. G., Rao, R. L., Dip, E. C., Pereira-Franchi, E. P., Cha, P., Jacobson, S., Broome, R., Cheng, L. I., Weiss, W., Prokai, L., Nguyen, V., Stover, C. K. & Sellman, B. R., Apr 2017, In: Antimicrobial agents and chemotherapy. 61, 4, 02456-16.

  Research output: Contribution to journal › Article › peer-review

  • MEDI4893 100%
  • Necrotizing Pneumonia 71%
  • Staphylococcal Pneumonia 64%
  • Ferrets 59%
  • Rabbits 32%
  30 Scopus citations

• TGFβ2 induces the formation of cross-linked actin networks (CLANs) in human trabecular meshwork cells through the smad and non-smad dependent pathways

  Montecchi-Palmer, M., Bermudez, J. Y., Webber, H. C., Patel, G. C., Clark, A. F. & Mao, W., Feb 2017, In: Investigative Ophthalmology and Visual Science. 58, 2, p. 1288-1295 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Trabecular Meshwork 100%
  • Transforming Growth Factors 78%
  • Actins 63%
  • Extracellular Signal-Regulated MAP Kinases 36%
  • JNK Mitogen-Activated Protein Kinases 28%
  38 Scopus citations

• The dual modulatory effects of efavirenz on GABA_A receptors are mediated via two distinct sites

  Huang, R., Chen, Z., Dolan, S., Schetz, J. A. & Dillon, G. H., 15 Jul 2017, In: Neuropharmacology. 121, p. 167-178 12 p.

  Research output: Contribution to journal › Article › peer-review

  • efavirenz 100%
  • GABA-A Receptors 80%
  • gamma-Aminobutyric Acid 28%
  • HIV-1 13%
  • GABA Agents 11%
  7 Scopus citations

• The hippocampus: detailed assessment of normative two-dimensional measurements, signal intensity, and subfield conspicuity on routine 3T T2-weighted sequences

  Middlebrooks, E. H., Quisling, R. G., King, M. A., Carney, P. R., Roper, S., Colon-Perez, L. M. & Mareci, T. H., 1 Oct 2017, In: Surgical and Radiologic Anatomy. 39, 10, p. 1149-1159 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hippocampus 100%
  • Reference Values 33%
  • Benchmarking 22%
  7 Scopus citations

• The impact of sleep and psychiatric symptoms on alcohol consequences among young adults

  Miller, M. B., Van Reen, E., Barker, D. H., Roane, B. M., Borsari, B., McGeary, J. E., Seifer, R. & Carskadon, M. A., 1 Mar 2017, In: Addictive Behaviors. 66, p. 138-144 7 p.

  Research output: Contribution to journal › Article › peer-review

  • sleep 100%
  • young adult 77%
  • Young Adult 74%
  • Sleep 72%
  • alcohol 70%
  15 Scopus citations

• The influence of vitamins E and C and exercise on brain aging

  Mock, J. T., Chaudhari, K., Sidhu, A. & Sumien, N., Aug 2017, In: Experimental Gerontology. 94, p. 69-72 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging 100%
  • Vitamin C 96%
  • Vitamin E 95%
  • Ascorbic Acid 79%
  • Oxidative Stress 79%
  10 Scopus citations

• The risk factors of 9-year follow-up on hypertension in middle-aged people in Tujia-Nationality settlement of China

  Liu, X., Liu, C., Schenck, H., Yi, X., Wang, H. & Shi, X., 1 Dec 2017, In: Journal of Human Hypertension. 31, 12, p. 838-842 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Middle Aged 100%
  • China 79%
  • Hypertension 64%
  • Cardiorespiratory Fitness 25%
  • Occupational Groups 21%
  6 Scopus citations

• The Risk Factors of High Blood Pressure among Young Adults in the Tujia-Nationality Settlement of China

  Liu, X., Xiang, Z., Shi, X., Schenck, H., Yi, X., Ni, R. & Liu, C., 2017, In: BioMed Research International. 2017, 8315603.

  Research output: Contribution to journal › Article › peer-review

  • Blood Pressure 100%
  • Young Adult 63%
  • China 63%
  • Blue 57%
  • Hypertension 51%
  5 Scopus citations

• Tissue transglutaminase elevates intraocular pressure in mice

  Raychaudhuri, U., Millar, J. C. & Clark, A. F., Dec 2017, In: Investigative Ophthalmology and Visual Science. 58, 14, p. 6197-6211 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • transglutaminase 2 100%
  • Trabecular Meshwork 87%
  • Intraocular Pressure 73%
  • Eye 46%
  • Lysine 27%
  13 Scopus citations

• Transethnic genome-wide scan identifies novel Alzheimer's disease loci

  Alzheimer’s Disease Genetics Consortium, Jul 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dementia 100%
  • Alzheimer Disease 77%
  • Genome 67%
  • Single Nucleotide Polymorphism 50%
  • Genome-Wide Association Study 41%
  95 Scopus citations

• Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma

  Nicholas, S. E., Rowsey, T. G., Priyadarsini, S., Mandal, N. A. & Karamichos, D., Aug 2017, In: PLoS ONE. 12, 8, e0182390.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • sphingosine kinase 100%
  • Sphingosine 94%
  • Corneal Stroma 94%
  • sphingosine 93%
  • Sphingolipid 91%
  11 Scopus citations

• Upregulation of the endothelin A (ET_A) receptor and its association with neurodegeneration in a rodent model of glaucoma

  McGrady, N. R., Minton, A. Z., Stankowska, D. L., He, S., Jefferies, H. B. & Krishnamoorthy, R. R., 1 Mar 2017, In: BMC Neuroscience. 18, 1, 27.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin A Receptors 100%
  • Intraocular Pressure 71%
  • Glaucoma 69%
  • Rodentia 61%
  • Up-Regulation 53%
  20 Scopus citations

• Water T₂ as an early, global and practical biomarker for metabolic syndrome: An observational cross-sectional study

  Robinson, M. D., Mishra, I., Deodhar, S., Patel, V., Gordon, K. V., Vintimilla, R., Brown, K., Johnson, L., O'Bryant, S. & Cistola, D. P., 19 Dec 2017, In: Journal of Translational Medicine. 15, 1, 258.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolic Syndrome 100%
  • Biological Marker 98%
  • Metabolic 88%
  • Water 72%
  • Cross-Sectional Studies 70%
  14 Scopus citations
• 2016

  A blood screening test for Alzheimer's disease

  O'Bryant, S. E., Edwards, M., Johnson, L., Hall, J., Villarreal, A. E., Britton, G. B., Quiceno, M., Cullum, C. M. & Graff-Radford, N. R., 2016, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3, p. 83-90 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematologic Tests 100%
  • Alzheimer Disease 74%
  • Forests 18%
  • Neurodegenerative Diseases 13%
  • Cognitive Dysfunction 13%
  50 Scopus citations

• A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease

  Tschiffely, A. E., Schuh, R. A., Prokai-Tatrai, K., Prokai, L. & Ottinger, M. A., 1 Jul 2016, In: Hormones and Behavior. 83, p. 39-44 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Transgenic Mice 80%
  • Estradiol 78%
  • Alzheimer Disease 69%
  • Brain 44%
  • Hormones 15%
  20 Scopus citations

• A depressive endophenotype for predicting cognitive decline among mexican American adults and elders

  Johnson, L. A., Gamboa, A., Vintimilla, R., Edwards, M., Hall, J., Weiser, B., Yadav, M., Dickensheets, T. & O'Bryant, S. E., 23 Aug 2016, In: Journal of Alzheimer's Disease. 54, 1, p. 201-206 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Endophenotypes 100%
  • Mexican Americans 97%
  • Cognitive Dysfunction 61%
  • cognitive impairment 61%
  • Memory 43%
  7 Scopus citations

• A fractal derivative model for the characterization of anomalous diffusion in magnetic resonance imaging

  Liang, Y., Ye, A. Q., Chen, W., Gatto, R. G., Colon-Perez, L., Mareci, T. H. & Magin, R. L., 1 Oct 2016, In: Communications in Nonlinear Science and Numerical Simulation. 39, p. 529-537 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Resonance Imaging 100%
  • Anomalous Diffusion 84%
  • Magnetic resonance 70%
  • Fractals 70%
  • Fractal 60%
  80 Scopus citations

• Allosteric modulati on of nicotinic acetylcholine receptors: The concept and therapeutic trends

  Uteshev, V. V., 1 Apr 2016, In: Current Pharmaceutical Design. 22, 14, p. 1986-1997 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotinic Receptors 100%
  • Acetylcholine 96%
  • Cholinergic 92%
  • Cholinergic Agents 50%
  • Antiinflammatory 34%
  13 Scopus citations

• Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

  Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In: PLoS ONE. 11, 2, e0148717.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome-Wide Association Study 100%
  • Alzheimer Disease 74%
  • Single Nucleotide Polymorphism 60%
  • Gene Expression 57%
  • Quantitative Trait Loci 30%
  65 Scopus citations

• A majority rule approach for region-of-interest-guided streamline fiber tractography

  Colon-Perez, L. M., Triplett, W., Bohsali, A., Corti, M., Nguyen, P. T., Patten, C., Mareci, T. H. & Price, C. C., 1 Dec 2016, In: Brain Imaging and Behavior. 10, 4, p. 1137-1147 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyramidal Tracts 100%
  • Internal Capsule 52%
  • Hand 45%
  • White Matter 36%
  • Cerebral Peduncle 31%
  12 Scopus citations

• A novel Alzheimer disease locus located near the gene encoding tau protein

  Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A., & 332 othersFievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., 1 Jan 2016, In: Molecular Psychiatry. 21, 1, p. 108-117 10 p.

  Research output: Contribution to journal › Article › peer-review

  • tau Proteins 100%
  • Single Nucleotide Polymorphism 66%
  • Alzheimer Disease 61%
  • Genes 32%
  • Exons 28%
  160 Scopus citations

• A novel luciferase assay for sensitively monitoring myocilin variants in cell culture

  Zadoo, S., Nguyen, A., Zode, G. & Hulleman, J. D., 1 Apr 2016, In: Investigative Ophthalmology and Visual Science. 57, 4, p. 1939-1950 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • trabecular meshwork-induced glucocorticoid response protein 100%
  • Luciferases 56%
  • Cell Culture Techniques 46%
  • Mutation 3%
  • Conditioned Culture Medium 3%
  9 Scopus citations

• Are positive allosteric modulators of α7 nAChRs clinically safe?

  Uteshev, V., 1 Jan 2016, In: Journal of Neurochemistry. 136, 2, p. 217-219 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotinic Receptors 100%
  • Cell Death 96%
  • Endoplasmic Reticulum 86%
  10 Scopus citations

• Artificial polymeric scaffolds as extracellular matrix substitutes for autologous conjunctival goblet cell expansion

  He, M., Storr-Paulsen, T., Wang, A. L., Ghezzi, C. E., Wang, S., Fullana, M., Karamichos, D., Utheim, T. P., Islam, R., Griffith, M., Islam, M. M., Hodges, R. R., Wnek, G. E., Kaplan, D. L. & Dartt, D. A., Nov 2016, In: Investigative Ophthalmology and Visual Science. 57, 14, p. 6134-6146 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Goblet Cells 100%
  • Silk 71%
  • Extracellular Matrix 70%
  • polycaprolactone 47%
  • Polyethylene Terephthalates 34%
  17 Scopus citations

• A sex difference in oxidative stress and behavioral suppression induced by ethanol withdrawal in rats

  Jung, M. E. & Metzger, D. B., 1 Nov 2016, In: Behavioural Brain Research. 314, p. 199-214 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Sex Characteristics 100%
  • Ethanol 90%
  • Oxidative Stress 78%
  • Hippocampus 56%
  • Electron Transport Complex IV 55%
  15 Scopus citations

• Assessment of the genetic variance of late-onset Alzheimer's disease

  Alzheimer's Disease Genetics Consortium (ADGC), 1 May 2016, In: Neurobiology of Aging. 41, p. 200.e13-200.e20

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Single Nucleotide Polymorphism 61%
  • Netrin Receptors 30%
  • Multifactorial Inheritance 22%
  • Amyloid beta-Protein Precursor 21%
  46 Scopus citations

• B7-H4(B7x)-mediated cross-talk between glioma-initiating cells and macrophages via the IL6/JAK/STAT3 pathway lead to poor prognosis in glioma patients

  Yao, Y., Ye, H., Qi, Z., Mo, L., Yue, Q., Baral, A., Hoon, D. S. B., Vera, J. C., Heiss, J. D., Chen, C. C., Hua, W., Zhang, J., Jin, K., Wang, Y., Mao, Y., Zang, X. & Zhou, L., 1 Jun 2016, In: Clinical Cancer Research. 22, 11, p. 2778-2790 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioma 100%
  • Interleukin-6 83%
  • Macrophages 75%
  • Microglia 54%
  • Immunosuppressive Agents 30%
  107 Scopus citations

• Bcl-2, Bcl-xL, and p-AKT are involved in neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma

  Phatak, N. R., Stankowska, D. L. & Krishnamoorthy, R. R., 16 Aug 2016, In: Molecular vision. 22, p. 1048-1061 14 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Leukemia 100%
  • Ocular Hypertension 89%
  • B-Cell Lymphoma 73%
  • Neuroprotective Agents 72%
  • Retinal Ganglion Cells 71%
  17 Scopus citations

• BioWatch: A Noninvasive Wrist-Based Blood Pressure Monitor That Incorporates Training Techniques for Posture and Subject Variability

  Thomas, S. S., Nathan, V., Zong, C., Soundarapandian, K., Shi, X. & Jafari, R., Sep 2016, In: IEEE Journal of Biomedical and Health Informatics. 20, 5, p. 1291-1300 10 p., 7163275.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blood Pressure Monitors 100%
  • Blood pressure 78%
  • Posture 68%
  • Wrist 65%
  • Teaching 60%
  111 Scopus citations

• C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury

  Silverman, S. M., Kim, B. J., Howell, G. R., Miller, J., John, S. W. M., Wordinger, R. J. & Clark, A. F., 24 Mar 2016, In: Molecular Neurodegeneration. 11, 1, 24.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Reperfusion Injury 100%
  • Superior Colliculi 92%
  • Astrocytes 71%
  • Electroretinography 68%
  • Neuroglia 68%
  44 Scopus citations

• Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging

  Means, J. C., Gerdes, B. C., Kaja, S., Sumien, N., Payne, A. J., Stark, D. A., Borden, P. K., Price, J. L. & Koulen, P., 1 Sep 2016, In: Neurochemical Research. 41, 9, p. 2278-2288 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurofibrillary Tangles 100%
  • Caspases 83%
  • Caspase 3 73%
  • Cognitive Dysfunction 67%
  • Alzheimer Disease 64%
  25 Scopus citations

• CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation

  Racine, R. R., Manalo, N. A., Hall, J. M. F., Dibas, A., Raffel, G. D. & Mummert, M. E., 1 Jul 2016, In: Biochemistry and Biophysics Reports. 6, p. 172-178 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphoric Monoester Hydrolases 100%
  • Calcium(0) 75%
  • Calcium 67%
  • Cell Proliferation 64%
  • Modification 54%
  6 Scopus citations

• Characterization of Alzheimer's Disease and Mild Cognitive Impairment in Older Adults in Panama

  Villarreal, A. E., Grajales, S., O'Bryant, S. E., Edwards, M., López, L., Montalván, A. & Britton, G. B., 1 Jan 2016, In: Journal of Alzheimer's Disease. 54, 3, p. 897-901 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Panama 100%
  • cognitive impairment 81%
  • dementia 67%
  • Cognitive Dysfunction 54%
  • Alzheimer Disease 51%
  4 Scopus citations

• Cholinergic neurons in the basal forebrain promote wakefulness by actions on neighboring non-cholinergic neurons: An opto-dialysis study

  Zant, J. C., Kim, T., Prokai, L., Szarka, S., McNally, J., McKenna, J. T., Shukla, C., Yang, C., Kalinchuk, A. V., McCarley, R. W., Brown, R. E. & Basheer, R., 10 Feb 2016, In: Journal of Neuroscience. 36, 6, p. 2057-2067 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Basal Forebrain 100%
  • Cholinergic Neurons 96%
  • Wakefulness 91%
  • Dialysis 67%
  • Neurons 48%
  71 Scopus citations

• Common lung microbiome identified among mechanically ventilated surgical patients

  Smith, A. D., Zhang, Y., Barber, R. C., Minshall, C. T., Huebinger, R. M. & Allen, M. S., Nov 2016, In: PLoS ONE. 11, 11, e0166313.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microbiota 100%
  • microbiome 98%
  • lungs 80%
  • Bronchoalveolar Lavage 72%
  • Bacteria 68%
  6 Scopus citations

• Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment

  Wei, X., Gao, H., Zou, J., Liu, X., Chen, D., Liao, J., Xu, Y., Ma, L., Tang, B., Zhang, Z., Cai, X., Jin, K., Xia, Y. & Wang, Q., 1 Nov 2016, In: Molecular Neurobiology. 53, 9, p. 5876-5892 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Memantine 100%
  • Cytoplasmic and Nuclear Receptors 75%
  • Oxidopamine 64%
  • PC12 Cells 52%
  • Inflammation 43%
  59 Scopus citations

• Critical role of alpha-toxin and protective effects of its neutralization by a human antibody in acute bacterial skin and skin structure infections

  Le, V. T. M., Tkaczyk, C., Chau, S., Rao, R. L., Dip, E. C., Pereira-Franchi, E. P., Cheng, L., Lee, S., Koelkebeck, H., Hilliard, J. J., Yu, X. Q., Datta, V., Nguyen, V., Weiss, W., Prokai, L., O'Day, T., Stover, C. K., Sellman, B. R. & Diep, B. A., 1 Oct 2016, In: Antimicrobial agents and chemotherapy. 60, 10, p. 5640-5648 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Antibodies 100%
  • Skin 99%
  • Infections 86%
  • MEDI4893 65%
  • Methicillin-Resistant Staphylococcus aureus 30%
  27 Scopus citations

• Crosstalk between TGFβ and Wnt signaling pathways in the human trabecular meshwork

  Webber, H. C., Bermudez, J. Y., Sethi, A., Clark, A. F. & Mao, W., 1 Jul 2016, In: Experimental eye research. 148, p. 97-102 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Trabecular Meshwork 100%
  • Wnt Signaling Pathway 85%
  • Luciferases 56%
  • Open Angle Glaucoma 51%
  • Catenins 37%
  34 Scopus citations

• Deciphering the role of Emx1 in neurogenesis: A neuroproteomics approach

  Kobeissy, F. H., Hansen, K., Neumann, M., Fu, S., Jin, K. & Liu, J., 17 Oct 2016, In: Frontiers in Molecular Neuroscience. 9, OCT2016, 98.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neural Stem Cells 100%
  • Neurogenesis 94%
  • Protein Interaction Maps 37%
  • Brain 29%
  • Knockout Mice 27%
  10 Scopus citations

• Depressed basal hypothalamic neuronal activity in type-1 diabetic mice is correlated with proinflammatory secretion of HMBG1

  Thinschmidt, J. S., Colon Perez, L. M., Febo, M., Caballero, S., King, M. A., White, F. A. & Grant, M. B., 26 Feb 2016, In: Neuroscience letters. 615, p. 21-27 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Streptozocin 100%
  • Animals 74%
  • Insulin-Like Growth Factor Binding Protein 2 70%
  • Insulin-Like Growth Factor Binding Protein 3 62%
  • Manganese 59%
  11 Scopus citations

• Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

  Acharya, S., Rogers, P., Krishnamoorthy, R. R., Stankowska, D. L., Dias, H. V. R. & Yorio, T., 1 Mar 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 5, p. 1490-1494 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ocular 100%
  • Optic Nerve Diseases 97%
  • Prodrug 83%
  • Carbamates 54%
  • Photoreceptor Cells 49%
  17 Scopus citations

• Direct analysis in real time (DART) of an organothiophosphate at ultrahigh resolution by fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry

  Prokai, L. & Stevens, S. M., 16 Jan 2016, In: International journal of molecular sciences. 17, 1, 116.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Organothiophosphates 100%
  • Cyclotron resonance 83%
  • Cyclotrons 69%
  • Mass spectrometry 58%
  • Fourier Analysis 53%
  6 Scopus citations